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Lennox-Gastaut Syndrome Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

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    Report

  • 128 Pages
  • May 2024
  • Region: Global
  • IMARC Group
  • ID: 5970242
The 7 major Lennox-Gastaut syndrome markets are expected to exhibit a CAGR of 4.63% during 2023-2034.

The Lennox-Gastaut syndrome market has been comprehensively analyzed in this report titled "Lennox-Gastaut Syndrome Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Lennox-Gastaut syndrome (LGS) refers to a rare and severe form of epilepsy that primarily affects children between the ages of 3 and 5. It is characterized by multiple types of seizures, cognitive impairment, and distinct electroencephalogram (EEG) patterns. Children suffering from the ailment often experience a variety of seizure types, including tonic, atonic, and absence seizures, which can lead to sudden falls (drop attacks) and frequent episodes of loss of awareness. The cognitive and developmental challenges associated with LGS can range from mild to severe, affecting learning, behavior, and overall quality of life. The diagnosis of the illness involves a comprehensive evaluation of medical history, clinical symptoms, and EEG findings. The hallmark EEG pattern of this ailment typically includes slow spike-and-wave complexes and multifocal epileptic discharges. As various seizure types and cognitive issues overlap with numerous other epilepsy syndromes, accurately diagnosing LGS can be complex and requires expertise from neurologists and epileptologists.

The increasing incidences of brain abnormalities that can disrupt normal brain function and contribute to the development of seizures are primarily driving the Lennox-Gastaut syndrome market. In addition to this, the inflating utilization of efficacious pharmaceutical interventions like antiepileptic drugs, benzodiazepines, and cannabinoid-based medications to manage seizures and ameliorate symptomatology is also creating a positive outlook for the market. Moreover, the widespread adoption of specialized medical devices, such as vagus nerve stimulators, which are designed to modulate brain activity and reduce seizure frequency in individuals suffering from the ailment, is further bolstering the market growth. Apart from this, the rising usage of comprehensive therapeutic approaches encompassing ketogenic diets and non-pharmacological interventions owing to their numerous advantages, including optimizing treatment outcomes, fostering cognitive development, and enhancing overall quality of life, is acting as another significant growth-inducing factor. Additionally, the emerging popularity of progressive neuromodulation techniques like responsive neurostimulation, calibrated to detect and counteract seizure activity in patients, is also augmenting the market growth. Furthermore, the escalating application of advanced precision medicine avenues, including targeted genetic therapies tailored to rectify or replace malfunctioning genes associated with the disorder, is expected to drive the Lennox-Gastaut syndrome market during the forecast period.

This report provides an exhaustive analysis of the Lennox-Gastaut syndrome market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for Lennox-Gastaut syndrome and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the Lennox-Gastaut syndrome market in any manner.

Time Period of the Study

  • Base Year: 2023
  • Historical Period: 2018-2023
  • Market Forecast: 2024-2034

Countries Covered

  • United States
  • Germany
  • France
  • United Kingdom
  • Italy
  • Spain
  • Japan

Analysis Covered Across Each Country

  • Historical, current, and future epidemiology scenario
  • Historical, current, and future performance of the Lennox-Gastaut syndrome market
  • Historical, current, and future performance of various therapeutic categories in the market
  • Sales of various drugs across the Lennox-Gastaut syndrome market

Competitive Landscape:

This report also provides a detailed analysis of the current Lennox-Gastaut syndrome marketed drugs and late-stage pipeline drugs.

In-Market Drugs

  • Drug Overview
  • Mechanism of Action
  • Regulatory Status
  • Clinical Trial Results
  • Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

  • Drug Overview
  • Mechanism of Action
  • Regulatory Status
  • Clinical Trial Results
  • Drug Uptake and Market Performance
*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:

Market Insights

  • How has the Lennox-Gastaut syndrome market performed so far and how will it perform in the coming years?
  • What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
  • What was the country-wise size of the Lennox-Gastaut syndrome market across the seven major markets in 2023 and what will it look like in 2034?
  • What is the growth rate of the Lennox-Gastaut syndrome market across the seven major markets and what will be the expected growth over the next ten years?
  • What are the key unmet needs in the market?

Epidemiology Insights

  • What is the number of prevalent cases (2018-2034) of Lennox-Gastaut syndrome across the seven major markets?
  • What is the number of prevalent cases (2018-2034) of Lennox-Gastaut syndrome by age across the seven major markets?
  • What is the number of prevalent cases (2018-2034) of Lennox-Gastaut syndrome by gender across the seven major markets?
  • How many patients are diagnosed (2018-2034) with Lennox-Gastaut syndrome across the seven major markets?
  • What is the size of the Lennox-Gastaut syndrome patient pool (2018-2023) across the seven major markets?
  • What would be the forecasted patient pool (2024-2034) across the seven major markets?
  • What are the key factors driving the epidemiological trend of Lennox-Gastaut syndrome?
  • What will be the growth rate of patients across the seven major markets?

Lennox-Gastaut Syndrome: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

  • What are the current marketed drugs and what are their market performance?
  • What are the key pipeline drugs and how are they expected to perform in the coming years?
  • How safe are the current marketed drugs and what are their efficacies?
  • How safe are the late-stage pipeline drugs and what are their efficacies?
  • What are the current treatment guidelines for Lennox-Gastaut syndrome drugs across the seven major markets?
  • Who are the key companies in the market and what are their market shares?
  • What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the Lennox-Gastaut syndrome market?
  • What are the key regulatory events related to the Lennox-Gastaut syndrome market?
  • What is the structure of clinical trial landscape by status related to the Lennox-Gastaut syndrome market?
  • What is the structure of clinical trial landscape by phase related to the Lennox-Gastaut syndrome market?
  • What is the structure of clinical trial landscape by route of administration related to the Lennox-Gastaut syndrome market?
This product will be updated with the latest data at the time of order. Consequently, dispatch time for this product will be 7-10 business days.

Table of Contents

1 Preface
2 Scope and Methodology
2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
2.3.1 Primary Sources
2.3.2 Secondary Sources
2.4 Market Estimation
2.4.1 Bottom-Up Approach
2.4.2 Top-Down Approach
2.5 Forecasting Methodology
3 Executive Summary
4 Lennox-Gastaut Syndrome - Introduction
4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence
5 Lennox-Gastaut Syndrome - Disease Overview
5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment
6 Patient Journey
7 Lennox-Gastaut Syndrome - Epidemiology and Patient Population
7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
7.2.1 Epidemiology Scenario (2018-2023)
7.2.2 Epidemiology Forecast (2024-2034)
7.2.3 Epidemiology by Age (???2018-2034)
7.2.4 Epidemiology by Gender (???2018-2034)
7.2.5 Diagnosed Cases (???2018-2034)
7.2.6 Patient Pool/Treated Cases (???2018-2034)
7.3 Epidemiology Scenario - United States
7.3.1 Epidemiology Scenario (2018-2023)
7.3.2 Epidemiology Forecast (2024-2034)
7.3.3 Epidemiology by Age (???2018-2034)
7.3.4 Epidemiology by Gender (???2018-2034)
7.3.5 Diagnosed Cases (???2018-2034)
7.3.6 Patient Pool/Treated Cases (???2018-2034)
7.4 Epidemiology Scenario - Germany
7.4.1 Epidemiology Scenario (2018-2023)
7.4.2 Epidemiology Forecast (2024-2034)
7.4.3 Epidemiology by Age (???2018-2034)
7.4.4 Epidemiology by Gender (???2018-2034)
7.4.5 Diagnosed Cases (???2018-2034)
7.4.6 Patient Pool/Treated Cases (???2018-2034)
7.5 Epidemiology Scenario - France
7.5.1 Epidemiology Scenario (2018-2023)
7.5.2 Epidemiology Forecast (2024-2034)
7.5.3 Epidemiology by Age (???2018-2034)
7.5.4 Epidemiology by Gender (???2018-2034)
7.5.5 Diagnosed Cases (???2018-2034)
7.5.6 Patient Pool/Treated Cases (???2018-2034)
7.6 Epidemiology Scenario - United Kingdom
7.6.1 Epidemiology Scenario (2018-2023)
7.6.2 Epidemiology Forecast (2024-2034)
7.6.3 Epidemiology by Age (???2018-2034)
7.6.4 Epidemiology by Gender (???2018-2034)
7.6.5 Diagnosed Cases (???2018-2034)
7.6.6 Patient Pool/Treated Cases (???2018-2034)
7.7 Epidemiology Scenario - Italy
7.7.1 Epidemiology Scenario (2018-2023)
7.7.2 Epidemiology Forecast (2024-2034)
7.7.3 Epidemiology by Age (???2018-2034)
7.7.4 Epidemiology by Gender (???2018-2034)
7.7.5 Diagnosed Cases (???2018-2034)
7.7.6 Patient Pool/Treated Cases (???2018-2034)
7.8 Epidemiology Scenario - Spain
7.8.1 Epidemiology Scenario (2018-2023)
7.8.2 Epidemiology Forecast (2024-2034)
7.8.3 Epidemiology by Age (???2018-2034)
7.8.4 Epidemiology by Gender (???2018-2034)
7.8.5 Diagnosed Cases (???2018-2034)
7.8.6 Patient Pool/Treated Cases (???2018-2034)
7.9 Epidemiology Scenario - Japan
7.9.1 Epidemiology Scenario (2018-2023)
7.9.2 Epidemiology Forecast (2024-2034)
7.9.3 Epidemiology by Age (???2018-2034)
7.9.4 Epidemiology by Gender (???2018-2034)
7.9.5 Diagnosed Cases (???2018-2034)
7.9.6 Patient Pool/Treated Cases (???2018-2034)
8 Lennox-Gastaut Syndrome - Treatment Algorithm, Guidelines, and Medical Practices
8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm
9 Lennox-Gastaut Syndrome - Unmet Needs10 Lennox-Gastaut Syndrome - Key Endpoints of Treatment
11 Lennox-Gastaut Syndrome - Marketed Products
11.1 List of Lennox-Gastaut Syndrome Marketed Drugs Across the Top 7 Markets
11.1.1 Epidiolex (Cannabidiol) - Greenwich Biosciences
11.1.1.1 Drug Overview
11.1.1.2 Mechanism of Action
11.1.1.3 Regulatory Status
11.1.1.4 Clinical Trial Results
11.1.1.5 Sales Across Major Markets
11.1.2 Fintepla (Fenfluramine) - Zogenix
11.1.2.1 Drug Overview
11.1.2.2 Mechanism of Action
11.1.2.3 Regulatory Status
11.1.2.4 Clinical Trial Results
11.1.2.5 Sales Across Major Markets
11.1.3 Banzel (Rufinamide) - Eisai
11.1.3.1 Drug Overview
11.1.3.2 Mechanism of Action
11.1.3.3 Regulatory Status
11.1.3.4 Clinical Trial Results
11.1.3.5 Sales Across Major Markets
11.1.4 Topamax (Topiramate) - Janssen Pharmaceuticals
11.1.4.1 Drug Overview
11.1.4.2 Mechanism of Action
11.1.4.3 Regulatory Status
11.1.4.4 Clinical Trial Results
11.1.4.5 Sales Across Major Markets
11.1.5 Lamictal (Lamotrigine) - GlaxoSmithKline
11.1.5.1 Drug Overview
11.1.5.2 Mechanism of Action
11.1.5.3 Regulatory Status
11.1.5.4 Clinical Trial Results
11.1.5.5 Sales Across Major Markets
Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report
12 Lennox-Gastaut Syndrome - Pipeline Drugs
12.1 List of Lennox-Gastaut Syndrome Pipeline Drugs Across the Top 7 Markets
12.1.1 Clemizole HCl - Epygenix
12.1.1.1 Drug Overview
12.1.1.2 Mechanism of Action
12.1.1.3 Clinical Trial Results
12.1.1.4 Safety and Efficacy
12.1.1.5 Regulatory Status
12.1.2 Soticlestat - Takeda
12.1.2.1 Drug Overview
12.1.2.2 Mechanism of Action
12.1.2.3 Clinical Trial Results
12.1.2.4 Safety and Efficacy
12.1.2.5 Regulatory Status
12.1.3 Carisbamate - SK Life Science
12.1.3.1 Drug Overview
12.1.3.2 Mechanism of Action
12.1.3.3 Clinical Trial Results
12.1.3.4 Safety and Efficacy
12.1.3.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report
13 Lennox-Gastaut Syndrome - Attribute Analysis of Key Marketed and Pipeline Drugs
14 Lennox-Gastaut Syndrome - Clinical Trial Landscape
14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events
15 Lennox-Gastaut Syndrome - Market Scenario
15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
15.2.1 Lennox-Gastaut Syndrome - Market Size
15.2.1.1 Market Size (2018-2023)
15.2.1.2 Market Forecast (2024-2034)
15.2.2 Lennox-Gastaut Syndrome - Market Size by Therapies
15.2.2.1 Market Size by Therapies (2018-2023)
15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
15.3.1 Lennox-Gastaut Syndrome - Market Size
15.3.1.1 Market Size (2018-2023)
15.3.1.2 Market Forecast (2024-2034)
15.3.2 Lennox-Gastaut Syndrome - Market Size by Therapies
15.3.2.1 Market Size by Therapies (2018-2023)
15.3.2.2 Market Forecast by Therapies (2024-2034)
15.3.3 Lennox-Gastaut Syndrome - Access and Reimbursement Overview
15.4 Market Scenario - Germany
15.4.1 Lennox-Gastaut Syndrome - Market Size
15.4.1.1 Market Size (2018-2023)
15.4.1.2 Market Forecast (2024-2034)
15.4.2 Lennox-Gastaut Syndrome - Market Size by Therapies
15.4.2.1 Market Size by Therapies (2018-2023)
15.4.2.2 Market Forecast by Therapies (2024-2034)
15.4.3 Lennox-Gastaut Syndrome - Access and Reimbursement Overview
15.5 Market Scenario - France
15.5.1 Lennox-Gastaut Syndrome - Market Size
15.5.1.1 Market Size (2018-2023)
15.5.1.2 Market Forecast (2024-2034)
15.5.2 Lennox-Gastaut Syndrome - Market Size by Therapies
15.5.2.1 Market Size by Therapies (2018-2023)
15.5.2.2 Market Forecast by Therapies (2024-2034)
15.5.3 Lennox-Gastaut Syndrome - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
15.6.1 Lennox-Gastaut Syndrome - Market Size
15.6.1.1 Market Size (2018-2023)
15.6.1.2 Market Forecast (2024-2034)
15.6.2 Lennox-Gastaut Syndrome - Market Size by Therapies
15.6.2.1 Market Size by Therapies (2018-2023)
15.6.2.2 Market Forecast by Therapies (2024-2034)
15.6.3 Lennox-Gastaut Syndrome - Access and Reimbursement Overview
15.7 Market Scenario - Italy
15.7.1 Lennox-Gastaut Syndrome - Market Size
15.7.1.1 Market Size (2018-2023)
15.7.1.2 Market Forecast (2024-2034)
15.7.2 Lennox-Gastaut Syndrome - Market Size by Therapies
15.7.2.1 Market Size by Therapies (2018-2023)
15.7.2.2 Market Forecast by Therapies (2024-2034)
15.7.3 Lennox-Gastaut Syndrome - Access and Reimbursement Overview
15.8 Market Scenario - Spain
15.8.1 Lennox-Gastaut Syndrome - Market Size
15.8.1.1 Market Size (2018-2023)
15.8.1.2 Market Forecast (2024-2034)
15.8.2 Lennox-Gastaut Syndrome - Market Size by Therapies
15.8.2.1 Market Size by Therapies (2018-2023)
15.8.2.2 Market Forecast by Therapies (2024-2034)
15.8.3 Lennox-Gastaut Syndrome - Access and Reimbursement Overview
15.9 Market Scenario - Japan
15.9.1 Lennox-Gastaut Syndrome - Market Size
15.9.1.1 Market Size (2018-2023)
15.9.1.2 Market Forecast (2024-2034)
15.9.2 Lennox-Gastaut Syndrome - Market Size by Therapies
15.9.2.1 Market Size by Therapies (2018-2023)
15.9.2.2 Market Forecast by Therapies (2024-2034)
15.9.3 Lennox-Gastaut Syndrome - Access and Reimbursement Overview
16 Lennox-Gastaut Syndrome - Recent Events and Inputs From Key Opinion Leaders
17 Lennox-Gastaut Syndrome Market - SWOT Analysis
17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats
18 Lennox-Gastaut Syndrome Market - Strategic Recommendations19 Appendix

Methodology

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