Celldex Therapeutics is a biopharmaceutical company that develops, manufactures, and commercializes novel therapeutics for human health care. The company's pipeline is comprised of therapeutic antibodies, antibody drug conjugates, immune system modulators and vaccines. The company's lead drug candidates are Rintega, Glembatumumab vedotin, Varlilumab and others. In 2005, Celldex was spun out of the New Jersey based biopharmaceutical company Medarex. It is now headquartered in Hampton, New Jersey.