4D Bioprinting Market Report 2025

This report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market’s historic and forecast market growth by geography.

The 4D printing in healthcare market size has grown strongly in recent years. It will grow from $8.65 billion in 2024 to $9.31 billion in 2025 at a compound annual growth rate (CAGR) of 7.6%. The growth in the historic period can be attributed to patient-specific solutions demand, bioprinting and tissue engineering, innovations in 3d printing technology, and materials development.

The 4D printing in healthcare market size is expected to see strong growth in the next few years. It will grow to $12.51 billion in 2029 at a compound annual growth rate (CAGR) of 7.7%. The growth in the forecast period can be attributed to personalized medicine advancements in material science, tissue engineering breakthroughs, and aging population and healthcare demands. Major trends in the forecast period include customized implants and prosthetics, responsive drug delivery systems, biocompatible and bioresorbable constructs, smart wearables for monitoring and treatment, tissue engineering and regenerative medicine.

The increasing number of surgeries is expected to propel the growth of 4D printing in the healthcare market going forward. 4D printing enables the creation of customized medical implants and devices tailored to individual patient anatomy. As the number of surgeries increases, there is a growing demand for personalized medical solutions to enhance surgical outcomes and patient recovery. 4D printing allows for the fabrication of complex structures that can adapt to specific patient needs, improving treatment efficacy and patient satisfaction. For instance, in June 2022, according to the American Society for Metabolic and Bariatric Surgery (ASMBS), a US-based non-profit medical organization, in 2021, approximately 262,893 bariatric surgeries were conducted, an increase from the 198,651 bariatric surgeries performed in 2020. Furthermore, in May 2023, according to Austin Publishing Group, a US-based publishing company, the global healthcare system served more than 300 million major surgical procedures each year. Therefore, the increasing number of surgeries is driving the growth of 4D printing in the healthcare market.

Major companies operating in 4D printing in the healthcare market are focusing on new technological products, such as 4D designs, to increase their profitability in the market. 4D designs refer to three-dimensional (3D) designs that incorporate the element of time as the fourth dimension. For instance, 4D Biomaterials, a UK-based biotechnology company launched 4Degra, a photocurable polycarbonate urethane polymer. This polymer is suitable for various medical device applications, from soft and flexible to firm and rigid, and is formulated using 4D Biomaterials' unique polycarbonate-urethane chemistry. DLP, LCD, SLA, and two-photon lithography are just a few of the photocurable additive micro and macro scale processes that can be cast, applied as coatings, or 3D print 4Degra resins.

In December 2023, 4DMedical, an Australia-based medical technology company, acquired Imbio, Inc. for an undisclosed amount. This acquisition is intended to strengthen 4DMedical's cardiothoracic imaging offerings by integrating AI-driven diagnostic tools with its existing imaging technology, ultimately enhancing respiratory and cardiac care, particularly for veterans and patients with lung disease. The move also supports the company’s efforts to expand in the U.S. market and improve screening capabilities. Imbio, Inc., based in the United States, specializes in advanced medical imaging AI solutions that provide quantitative analysis and insights for diagnosing and managing lung and cardiovascular diseases.

Major companies operating in the 4D printing in healthcare market are McKesson Corporation, Accenture plc., IBM Corporation, Oracle Corporation, Siemens Healthcare, Cognizant Technology Solutions Corporation, GE Healthcare, Quest Diagnostics, Dassault Systems, Cerner Corporation, Genpact Limited., Infor Inc., Allscripts Healthcare Solutions Inc., eClinicalWorks LLC, Athenahealth Inc., Avaya Inc., Stratasys Ltd, EOS GmbH Electro Optical Systems, 3D Systems Inc, The SSI Groups Inc., Materialise NV, CELLINK, CareCloud Corporation, Envisiontec Inc., Allevi Inc, Poietis SAS, Organovo Holdings Inc.

North America was the largest region in the 4D printing in healthcare market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the 4d printing in healthcare market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the 4D printing in healthcare market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The 4D printing in the healthcare market includes revenues earned by entities by providing services such as customizable implants and prosthetics, dynamic wound dressings, and patient-specific tissue engineering. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included. 4D printing in the healthcare market consists of sales of drug delivery systems, smart surgical tools, biodegradable stents, responsive orthopedic devices, and adaptive wearable devices. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

4D printing in healthcare refers to the fabrication of customized medical devices, implants, and structures using materials that can self-transform or change shape in response to external stimuli over time. This technology builds upon 3D printing by introducing an additional dimension of functionality, enabling the printed objects to alter their shape, properties, or functionality after manufacturing.

The main types of 4D printing in healthcare are fused deposition modeling (FDM), poly jet, stereolithography, and SLS. Fused deposition modeling (FDM) is a popular additive manufacturing technology used for 3D printing, its components include equipment, 3d printers, 3d bioprinters, programmable materials, shape-memory materials, hydrogels, living cells, and software and services, and it is used in hospitals and clinics, dental laboratories, and other end-users.

The main types of 4D printing in healthcare are fused deposition modeling (FDM), poly jet, stereolithography, and SLS. Fused deposition modeling (FDM) is a popular additive manufacturing technology used for 3D printing, its components include equipment, 3d printers, 3d bioprinters, programmable materials, shape-memory materials, hydrogels, living cells, and software and services, and it is used in hospitals and clinics, dental laboratories, and other end-users.

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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