Drug Summary
ACTEMRA (known as RoActemra in Europe) is a first-in-class anti-IL-6 receptor (aIL-6R) therapy developed by Roche and Chugai. Tocilizumab blocks the inflammatory protein IL-6. IL-6 is believed to play a key role in activating the inflammatory pathway that contributes to the signs and symptoms of Rheumatoid Arthritis (RA) and other inflammatory autoimmune conditions. ACTEMRA binds to IL-6 receptors, blocking the pro-inflammatory effect of IL-6 cytokines and improvIng joint pain and swelling from arthritis and other symptoms caused by inflammation.ACTEMRA (Tocilizumab) is a biologic medication currently approved to treat adults with moderately to severely active RA, adults with giant cell arteritis (GCA), and children ages two and above with Polyarticular Juvenile Idiopathic Arthritis (PJIA) or Systemic Juvenile Idiopathic Arthritis (SJIA). Biologic medications are proteins designed by humans that affect the immune system.
Dosage and Administration
Actemra may be used as monotherapy or concomitantly with methotrexate or other non-biologic DMARDs as an intravenous infusion or a subcutaneous injection.
Scope of the Report
The report provides insights into:
- A comprehensive product overview including the ACTEMRA description, mechanism of action, dosage and administration, research and development activities in Rheumatoid Arthritis.
- Elaborated details on ACTEMRA regulatory milestones and other development activities have been provided in this report.
- The report also highlights the ACTEMRA research and development activity in Rheumatoid Arthritis details across the United States, Europe and Japan.
- The report also covers the patents information with expiry timeline around ACTEMRA.
- The report contains forecasted sales of ACTEMRA for Rheumatoid Arthritis till 2032.
- Comprehensive coverage of the late-stage emerging therapies for Rheumatoid Arthritis.
- The report also features the SWOT analysis with analyst views for ACTEMRA in Rheumatoid Arthritis.
Methodology
The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by the research team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.ACTEMRA Analytical Perspective
In-depth ACTEMRA Market Assessment
This report provides a detailed market assessment of ACTEMRA in Rheumatoid Arthritis in the 7MM, i.e., United States, EU4 and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2023 to 2032.ACTEMRA Clinical Assessment
The report provides the clinical trials information of ACTEMRA for Rheumatoid Arthritis covering trial interventions, trial conditions, trial status, start and completion dates.Report Highlights
- In the coming years, the market scenario for Rheumatoid Arthritis is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
- The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence ACTEMRA dominance.
- Other emerging products for Rheumatoid Arthritis are expected to give tough market competition to ACTEMRA and launch of late-stage emerging therapies in the near future will significantly impact the market.
- A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of ACTEMRA in Rheumatoid Arthritis.
- This in-depth analysis of the forecasted sales data of ACTEMRA from 2023 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the ACTEMRA in Rheumatoid Arthritis.
Key Questions Answered
- What is the product type, route of administration and mechanism of action of ACTEMRA?
- What is the clinical trial status of the study related to ACTEMRA in Rheumatoid Arthritis and study completion date?
- What are the key collaborations, mergers and acquisitions, licensing and other activities related to the ACTEMRA development?
- What are the key designations that have been granted to ACTEMRA for Rheumatoid Arthritis?
- What is the forecasted market scenario of ACTEMRA for Rheumatoid Arthritis?
- What are the forecasted sales of ACTEMRA in the 7MM, including the United States, Europe, and Japan?
- What are the other emerging products available in Rheumatoid Arthritis and how are they giving competition to ACTEMRA for Rheumatoid Arthritis?
- Which are the late-stage emerging therapies under development for the treatment of Rheumatoid Arthritis?
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Table of Contents
1. Report Introduction2. ACTEMRA Overview in Rheumatoid Arthritis
2.1 Product Detail
2.2 Clinical Development
2.2.1 Clinical Studies
2.2.2 Clinical Trials Information
2.2.3 Safety and Efficacy
2.3 Regulatory milestones
2.4 Other Development Activities
2.5 Product Profile
3. Competitive Landscape (Marketed Therapies)
4. Competitive Landscape (Late-stage Emerging Therapies)*
5. ACTEMRA Market Assessment
5.1 Market Outlook of ACTEMRA in Rheumatoid Arthritis
5.2 7MM Market Analysis
5.2.1 Market Size of ACTEMRA in the 7MM for Rheumatoid Arthritis
5.3 Country-wise Market Analysis
5.3.1 Market Size of ACTEMRA in the United States for Rheumatoid Arthritis
5.3.2 Market Size of ACTEMRA in Germany for Rheumatoid Arthritis
5.3.3 Market Size of ACTEMRA in France for Rheumatoid Arthritis
5.3.4 Market Size of ACTEMRA in Italy for Rheumatoid Arthritis
5.3.5 Market Size of ACTEMRA in Spain for Rheumatoid Arthritis
5.3.6 Market Size of ACTEMRA in the United Kingdom for Rheumatoid Arthritis
5.3.7 Market Size of ACTEMRA in Japan for Rheumatoid Arthritis
6. SWOT Analysis
7. Analysts’ Views
8. Appendix
8.1 Bibliography
8.2 Report Methodology
9. Publisher Capabilities
10. Disclaimer
11. About the Publisher
12. Report Purchase Option
List of Tables
Table 1: ACTEMRA, Clinical Trial Description, 2022
Table 2: ACTEMRA : General Description
Table 3: Competitive Landscape (Marketed Therapies)
Table 4: Competitive Landscape (Emerging Therapies)
Table 5:ACTEMRA Market Size in the 7MM, in USD million (2019-2032)
Table 6:ACTEMRA Market Size in the United States, in USD million (2019-2032)
Table 7:ACTEMRA Market Size in Germany, in USD million (2019-2032)
Table 8:ACTEMRA Market Size in France, in USD million (2019-2032)
Table 9:ACTEMRA Market Size in Italy, in USD million (2019-2032)
Table 10:ACTEMRA Market Size in Spain, in USD million (2019-2032)
Table 11:ACTEMRA Market Size in the United Kingdom, in USD million (2019-2032)
Table 12:ACTEMRA Market Size in Japan, in USD million (2019-2032)
List of Figures
Figure 1: Market Size of ACTEMRA in the 7MM, in USD million (2019-2032)
Figure 2: Market Size of ACTEMRA in the United States, in USD million (2019-2032)
Figure 3: Market Size of ACTEMRA in Germany, in USD million (2019-2032)
Figure 4: Market Size of ACTEMRA in France, in USD million (2019-2032)
Figure 5: Market Size of ACTEMRA in Italy, in USD million (2019-2032)
Figure 6: Market Size of ACTEMRA in Spain, in USD million (2019-2032)
Figure 7: Market Size of ACTEMRA in the United Kingdom, in USD million (2019-2032)
Figure 8: Market Size of ACTEMRA in Japan, in USD million (2019-2032)