The antiviral combination therapy market size is expected to see strong growth in the next few years. It will grow to $76.92 billion in 2029 at a compound annual growth rate (CAGR) of 7.6%. The growth in the forecast period can be attributed to continued viral threats, research and development investments, global health preparedness, patient-centric approaches, potential expansion to new viral indications. Major trends in the forecast period include integration of nanotechnology, clinical trials for innovative combinations, collaborations for research and development, application of artificial intelligence in drug discovery, strategies for overcoming drug resistance.
The surge in viral diseases' occurrences is poised to drive the expansion of the antiviral combination therapy market in the forthcoming years. Viral diseases, stemming from microscopic infectious agents known as viruses, necessitate effective treatment approaches. Antiviral combination therapies play a crucial role in mitigating drug resistance risks and bolstering treatment efficiency. For instance, as of June 2022, the World Health Organization (WHO) reported a staggering 354 million individuals globally afflicted by hepatitis B or C infections, with an annual influx of 1.5 million new hepatitis C cases. This surge in viral infections underscores the imperative for advanced antiviral combination therapies to address these escalating health challenges.
The escalating demand for personalized medicine is set to fuel the growth of the antiviral combination therapy market. Personalized medicine, tailored to an individual's genetic or protein makeup, revolutionizes disease prevention, detection, and treatment. Variances in genetic compositions among individuals influence responses to antiviral therapies, prompting the need to identify these distinctions and optimize treatment strategies. For instance, in 2022, the US Food and Drug Administration (FDA) greenlit 12 personalized medicines, constituting roughly 34% of all newly approved therapeutic molecular entities, as highlighted by the Personalized Medicine Coalition. This burgeoning demand underscores the significance of tailoring treatment approaches, fostering the rise of the antiviral combination therapy market.
The market for antiviral combination therapy sees a rising focus on product innovation. Key companies are actively engaged in developing novel technological solutions to fortify their market standing. Gilead Sciences, Inc., a US-based biopharmaceutical firm, received FDA approval in December 2022 for Sunlenca (lenacapavir) in combination with other antiretroviral(s) to treat heavily treatment-experienced (HTE) adults with multi-drug-resistant (MDR) HIV-1 infection.
Major companies in the antiviral combination therapy market are concentrating on innovative solutions, such as antiviral therapies, to enhance treatment efficacy, improve patient outcomes, and tackle the increasing challenge of viral resistance. Antiviral therapies are treatments aimed at inhibiting the development or replication of viruses, thus managing viral infections. For example, in October 2023, Gilead Sciences, Inc., a biopharmaceutical company based in the US, formed a partnership with Assembly Biosciences Inc., a US-based biotechnology company, to develop innovative antiviral therapeutics aimed at serious viral diseases. This collaboration is focused on the research and development of novel antiviral therapies, initially concentrating on Assembly Bio's established areas, which include herpesviruses, hepatitis B virus (HBV), and hepatitis D virus (HDV).
In February 2023, Tonix Pharmaceuticals Holding Corporation, a US-based pharmaceutical company specializing in the development of novel therapies and vaccines for central nervous system disorders and infectious diseases, successfully acquired a preclinical infectious disease portfolio from Healion Bio Inc. for $1.2 million. This strategic acquisition is aimed at expanding Tonix Pharmaceuticals' overall portfolio, incorporating a range of next-generation antiviral technology assets. The newly acquired assets include a class of broad-spectrum small molecule oral antiviral drug candidates with a novel host-directed mechanism of action. These candidates can be utilized either as monotherapy or in combination with other antivirals. Healion Bio Inc., the source of the acquired portfolio, is a US-based biotechnology company dedicated to the manufacturing and development of medicines for the treatment and prevention of infectious diseases.
Major companies operating in the antiviral combination therapy market include AbbVie Inc., Bristol-Myers Squibb Company, Celltrion Inc., Cipla Inc., F. Hoffmann-La Roche Ltd., Gilead Sciences Inc., GlaxoSmithKline plc, Janssen Global Services LLC, Merck & Co. Inc., Mylan N.V., Aurobindo Pharma Limited, Dr. Reddy's Laboratories Limited, Novartis International AG, Pfizer Inc., Teva Pharmaceutical Industries Ltd., Atea Pharmaceuticals Inc., AstraZeneca plc, Eli Lilly and Company, Moderna Inc., Regeneron Pharmaceuticals Inc., Sanofi S.A., Takeda Pharmaceutical Company Limited, Vir Biotechnology Inc., Johnson & Johnson, Roche Holding AG, Sun Pharmaceutical Industries Ltd., Hetero Drugs Limited, Macleods Pharmaceuticals Ltd., Emcure Pharmaceuticals Ltd., AuroMedics Pharma LLC, Alembic Pharmaceuticals Limited, Zydus lifescience Ltd., Strides Pharma Science Limited, Glenmark Pharmaceuticals Inc., Lupin Pharmaceuticals Inc.
North America was the largest region in the antiviral combination therapy market in 2024. Asia-Pacific is expected to be the fastest-growing region in the global antiviral combination therapy market report during the forecast period. The regions covered in the antiviral combination therapy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the antiviral combination therapy market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
Antiviral combination therapy is a strategic approach involving the use of multiple antiviral medications to effectively address viral infections. This method enhances treatment outcomes by targeting various stages of the virus's life cycle, ultimately minimizing the risk of drug resistance.
The primary categories of antiviral combination therapy are branded and generic. Branded antiviral combination therapies are medications manufactured and marketed under a specific brand name by the manufacturer, holding regulatory approval through a new drug application. These formulations typically consist of a combination of two or more antiviral agents and are employed in treating diverse viral infections, including Human Immunodeficiency Virus (HIV), hepatitis C, and influenza. Examples of branded antiviral combination therapies include Atripla, Harvoni, Complera, Symfi Lo, and Xofluza. These combinations incorporate various drug classes, such as nucleotide reverse transcriptase inhibitors, non-nucleotide reverse transcriptase inhibitors, integrase inhibitors, nucleotide reverse transcriptase inhibitors, and protease inhibitors. They are administered through oral and intravenous routes and are distributed through hospital pharmacies, retail pharmacies, and other channels for the treatment of human immunodeficiency virus, hepatitis, and other viral indications.
The antiviral combination therapy market research report is one of a series of new reports that provides antiviral combination therapy market statistics, including the antiviral combination therapy industry’s global market size, regional shares, competitors with an antiviral combination therapy market share, detailed antiviral combination therapy market segments, market trends, and opportunities, and any further data you may need to thrive in the antiviral combination therapy industry. This antiviral combination therapy market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.
The antiviral combination therapy market consists of sales of protease inhibitors, reverse transcriptase inhibitors and integrase inhibitors. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
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Table of Contents
Executive Summary
Antiviral Combination Therapy Global Market Report 2025 provides strategists, marketers and senior management with the critical information they need to assess the market.This report focuses on antiviral combination therapy market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
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Description
Where is the largest and fastest growing market for antiviral combination therapy? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The antiviral combination therapy market global report answers all these questions and many more.The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market’s historic and forecast market growth by geography.
- The market characteristics section of the report defines and explains the market.
- The market size section gives the market size ($b) covering both the historic growth of the market, and forecasting its development.
- The forecasts are made after considering the major factors currently impacting the market. These include:
- The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.
- Market segmentations break down the market into sub markets.
- The regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth. It covers the growth trajectory of COVID-19 for all regions, key developed countries and major emerging markets.
- The competitive landscape chapter gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
- The trends and strategies section analyses the shape of the market as it emerges from the crisis and suggests how companies can grow as the market recovers.
Scope
Markets Covered:
1) By Type: Branded; Generic2) By Drug Combination: Nucleotide Reverse Transcriptase Inhibitors/Non-Nucleotide Reverse Transcriptase Inhibitors; Integrase Inhibitor/Nucleotide Reverse Transcriptase Inhibitors; Nucleotide Reverse Transcriptase Inhibitors; Nucleotide Reverse Transcriptase Inhibitors/Protease Inhibitor; Other Drug Combinations
3) By Route of Administration: Oral; Intravenous
4) By Distribution Channel: Hospital Pharmacies; Retail Pharmacies; Other Distribution Channels
5) By Indication: Human Immunodeficiency Virus; Hepatitis; Other Indications
Subsegments:
1) By Branded: Single Brand Combinations; Combination Therapies With Brand Recognition2) By Generic: Generic Fixed-Dose Combinations; Generic Drug Combinations With Similar Efficacy
Key Companies Mentioned: AbbVie Inc.; Bristol-Myers Squibb Company; Celltrion Inc.; Cipla Inc.; F. Hoffmann-La Roche Ltd.
Countries: Australia; Brazil; China; France; Germany; India; Indonesia; Japan; Russia; South Korea; UK; USA; Canada; Italy; Spain
Regions: Asia-Pacific; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
Time Series: Five years historic and ten years forecast.
Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita.
Data Segmentation: Country and regional historic and forecast data, market share of competitors, market segments.
Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.
Delivery Format: PDF, Word and Excel Data Dashboard.
Companies Mentioned
- AbbVie Inc.
- Bristol-Myers Squibb Company
- Celltrion Inc.
- Cipla Inc.
- F. Hoffmann-La Roche Ltd.
- Gilead Sciences Inc.
- GlaxoSmithKline plc
- Janssen Global Services LLC
- Merck & Co. Inc.
- Mylan N.V.
- Aurobindo Pharma Limited
- Dr. Reddy's Laboratories Limited
- Novartis International AG
- Pfizer Inc.
- Teva Pharmaceutical Industries Ltd.
- Atea Pharmaceuticals Inc.
- AstraZeneca plc
- Eli Lilly and Company
- Moderna Inc.
- Regeneron Pharmaceuticals Inc.
- Sanofi S.A.
- Takeda Pharmaceutical Company Limited
- Vir Biotechnology Inc.
- Johnson & Johnson
- Roche Holding AG
- Sun Pharmaceutical Industries Ltd.
- Hetero Drugs Limited
- Macleods Pharmaceuticals Ltd.
- Emcure Pharmaceuticals Ltd.
- AuroMedics Pharma LLC
- Alembic Pharmaceuticals Limited
- Zydus lifescience Ltd.
- Strides Pharma Science Limited
- Glenmark Pharmaceuticals Inc.
- Lupin Pharmaceuticals Inc.
Table Information
Report Attribute | Details |
---|---|
No. of Pages | 200 |
Published | February 2025 |
Forecast Period | 2025 - 2029 |
Estimated Market Value ( USD | $ 57.3 Billion |
Forecasted Market Value ( USD | $ 76.92 Billion |
Compound Annual Growth Rate | 7.6% |
Regions Covered | Global |
No. of Companies Mentioned | 35 |