3 Executive Summary
Figure 9 Cartilage Repair/Cartilage Regeneration Market, by Treatment Modality, 2023 vs. 2028 (USD Million)
Figure 10 Cartilage Repair/Cartilage Regeneration Market, by Application, 2023 vs. 2028 (USD Million)
Figure 11 Cartilage Repair/Cartilage Regeneration Market, by Application Site, 2023 vs. 2028 (USD Million)
Figure 12 Cartilage Repair/Cartilage Regeneration Market: Geographic Snapshot
5 Market Overview
5.1 Introduction
5.2 Market Dynamics
Figure 16 Cartilage Repair/Cartilage Regeneration Market: Drivers, Restraints, Opportunities, and Challenges
5.2.1 Market Drivers
5.2.1.1 Increasing Incidence of Osteoarthritis
5.2.1.2 Increasing Research Funding and Investments
5.2.1.3 Rising Number of Sports and Accident-Related Orthopedic Injuries
5.2.2 Restraints
5.2.2.1 High Cost of Cartilage Repair Surgeries
5.2.2.2 Unfavorable Reimbursement Scenario
5.2.3 Opportunities
5.2.3.1 Technological Advancements
5.2.3.2 Developments in Regenerative Medicine
5.2.4 Challenges
5.2.4.1 Limitations of Cartilage-based Stem Cell Products
5.2.4.2 Need for Skilled Personnel
5.3 Supply Chain Analysis
Figure 17 Distribution - Key Strategy Preferred by Prominent Companies
5.4 Regulatory Landscape
5.4.1 Introduction
5.4.2 North America
Table 3 Classification Based on Submission Required for Regulatory Approval
5.4.3 Europe
5.4.4 Asia-Pacific
5.5 Patent Analysis
Figure 18 Patent Analysis for Cartilage Repair/Cartilage Regeneration Market
5.6 Pipeline Analysis
5.6.1 Pipeline Analysis, by Clinical Trial Phase
Figure 19 Cartilage Repair Candidate Products in Clinical Phases One to Four
Table 4 Indicative List of Candidates in Clinical Trials
5.7 Technology Analysis
6 Cartilage Repair/Cartilage Regeneration Market, by Treatment Modality
6.1 Introduction
Table 5 Cartilage Repair/Cartilage Regeneration Market, by Treatment Modality, 2021-2028 (USD Million)
6.2 Cell-based Cartilage Repair/Cartilage Regeneration
Table 6 Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 7 Cell-based Cartilage Repair/Cartilage Regeneration Market, by Region, 2021-2028 (USD Million)
Table 8 North America: Cell-based Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
Table 9 Europe: Cell-based Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
Table 10 Asia-Pacific: Cell-based Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
6.2.1 Chondrocyte Transplantation
6.2.1.1 Cost-Effectiveness to Support Market Growth
Table 11 Chondrocyte Transplantation Market, by Region, 2021-2028 (USD Million)
Table 12 North America: Chondrocyte Transplantation Market, by Country, 2021-2028 (USD Million)
6.2.2 Growth Factors
6.2.2.1 Promising Results Associated with Growth Factors to Drive Market
Table 13 Growth Factors Market, by Region, 2021-2028 (USD Million)
Table 14 North America: Growth Factors Market, by Country, 2021-2028 (USD Million)
6.2.3 Stem Cells
6.2.3.1 Advancements in Stem Cell-based Tissue Engineering to Support Market Growth
Table 15 Stem Cells Market, by Region, 2021-2028 (USD Million)
Table 16 North America: Stem Cells Market, by Country, 2021-2028 (USD Million)
6.3 Non-Cell-based Cartilage Repair/Cartilage Regeneration
Table 17 Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 18 Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Region, 2021-2028 (USD Million)
Table 19 North America: Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
Table 20 Europe: Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
Table 21 Asia-Pacific: Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
6.3.1 Tissue Scaffolds
6.3.1.1 Benefits of One-Step Procedure Likely to Boost Market Growth
Table 22 Tissue Scaffolds Market, by Region, 2021-2028 (USD Million)
6.3.2 Cell-Free Composites
6.3.2.1 Increasing Research to Support Market Growth
Table 23 Cell-Free Composites Market, by Region, 2021-2028 (USD Million)
7 Cartilage Repair/Cartilage Regeneration Market, by Application Site
7.1 Introduction
Table 24 Cartilage Repair/Cartilage Regeneration Market, by Application Site, 2021-2028 (USD Million)
7.2 Knee
7.2.1 Increasing Cases of Knee Arthroscopy to Drive Market Growth
Table 25 Knee Cartilage Repair/Cartilage Regeneration Market, by Region, 2021-2028 (USD Million)
Table 26 North America: Knee Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
Table 27 Europe: Knee Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
Table 28 Asia-Pacific: Knee Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
7.3 Hip
7.3.1 Increasing Adoption of Minimally Invasive Arthroscopy Procedures to Support Market Growth
Table 29 Hip Cartilage Repair/Cartilage Regeneration Market, by Region, 2021-2028 (USD Million)
Table 30 North America: Hip Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
Table 31 Europe: Hip Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
Table 32 Asia-Pacific: Hip Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
7.4 Ankle & Foot
7.4.1 Increasing Sports Injuries to Drive Demand
Table 33 Ankle & Foot Cartilage Repair/Cartilage Regeneration Market, by Region, 2021-2028 (USD Million)
Table 34 North America: Ankle & Foot Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
Table 35 Europe: Ankle & Foot Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
7.5 Other Application Sites
Table 36 Cartilage Repair/Cartilage Regeneration Market for Other Application Sites, by Region, 2021-2028 (USD Million)
Table 37 North America: Cartilage Repair/Cartilage Regeneration Market for Other Application Sites, by Country, 2021-2028 (USD Million)
8 Cartilage Repair/Cartilage Regeneration Market, by Application
8.1 Introduction
Table 38 Cartilage Repair/Cartilage Regeneration Market, by Application, 2021-2028 (USD Million)
8.2 Hyaline Cartilage
8.2.1 Hyaline Cartilage Segment to Hold Larger Market Share
Table 39 Hyaline Cartilage Repair/Cartilage Regeneration Market, by Region, 2021-2028 (USD Million)
Table 40 North America: Hyaline Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
Table 41 Europe: Hyaline Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
Table 42 Asia-Pacific: Hyaline Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
8.3 Fibrocartilage
8.3.1 Support and Strength Advantages for Surrounding Structures to Drive Market
Table 43 Fibrocartilage Repair/Regeneration Market, by Region, 2021-2028 (USD Million)
Table 44 North America: Fibrocartilage Repair/Regeneration Market, by Country, 2021-2028 (USD Million)
Table 45 Europe: Fibrocartilage Repair/Regeneration Market, by Country, 2021-2028 (USD Million)
Table 46 Asia-Pacific: Fibrocartilage Repair/Regeneration Market, by Country, 2021-2028 (USD Million)
9 Cartilage Repair/Cartilage Regeneration Market, by Region
9.1 Introduction
Table 47 Cartilage Repair/Cartilage Regeneration Market, by Region, 2021-2028 (USD Million)
9.2 North America
9.2.1 North America: Recession Impact
Figure 20 North America: Cartilage Repair/Cartilage Regeneration Market Snapshot
Table 48 North America: Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
Table 49 North America: Cartilage Repair/Cartilage Regeneration Market, by Treatment Modality, 2021-2028 (USD Million)
Table 50 North America: Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 51 North America: Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 52 North America: Cartilage Repair/Cartilage Regeneration Market, by Application, 2021-2028 (USD Million)
Table 53 North America: Cartilage Repair/Cartilage Regeneration Market, by Application Site, 2021-2028 (USD Million)
9.2.2 US
9.2.2.1 Increasing Incidence of Osteoporosis to Drive Market
Table 54 US: Cartilage Repair/Cartilage Regeneration Market, by Treatment Modality, 2021-2028 (USD Million)
Table 55 US: Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 56 US: Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 57 US: Cartilage Repair/Cartilage Regeneration Market, by Application, 2021-2028 (USD Million)
Table 58 US: Cartilage Repair/Cartilage Regeneration Market, by Application Site, 2021-2028 (USD Million)
9.2.3 Canada
9.2.3.1 Increasing Investments in Regenerative Medicine Research to Drive Market
Table 59 Canada: Cartilage Repair/Cartilage Regeneration Market, by Treatment Modality, 2021-2028 (USD Million)
Table 60 Canada: Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 61 Canada: Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 62 Canada: Cartilage Repair/Cartilage Regeneration Market, by Application, 2021-2028 (USD Million)
Table 63 Canada: Cartilage Repair/Cartilage Regeneration Market, by Application Site, 2021-2028 (USD Million)
9.3 Europe
9.3.1 Europe: Recession Impact
Table 64 Europe: Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
Table 65 Europe: Cartilage Repair/Cartilage Regeneration Market, by Treatment Modality, 2021-2028 (USD Million)
Table 66 Europe: Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 67 Europe: Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 68 Europe: Cartilage Repair/Cartilage Regeneration Market, by Application, 2021-2028 (USD Million)
Table 69 Europe: Cartilage Repair/Cartilage Regeneration Market, by Application Site, 2021-2028 (USD Million)
9.3.2 Germany
9.3.2.1 Strong R&D Base and Focus on Minimally Invasive Surgeries to Support Market Growth
Table 70 Germany: Cartilage Repair/Cartilage Regeneration Market, by Treatment Modality, 2021-2028 (USD Million)
Table 71 Germany: Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 72 Germany: Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 73 Germany: Cartilage Repair/Cartilage Regeneration Market, by Application, 2021-2028 (USD Million)
Table 74 Germany: Cartilage Repair/Cartilage Regeneration Market, by Application Site, 2021-2028 (USD Million)
9.3.3 UK
9.3.3.1 Rising Prevalence of Joint Diseases to Boost Demand
Table 75 UK: Cartilage Repair/Cartilage Regeneration Market, by Treatment Modality, 2021-2028 (USD Million)
Table 76 UK: Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 77 UK: Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 78 UK: Cartilage Repair/Cartilage Regeneration Market, by Application, 2021-2028 (USD Million)
Table 79 UK: Cartilage Repair/Cartilage Regeneration Market, by Application Site, 2021-2028 (USD Million)
9.3.4 France
9.3.4.1 Rising Degenerative Disease and Healthcare Expenditure to Drive Market
Table 80 France: Cartilage Repair/Cartilage Regeneration Market, by Treatment Modality, 2021-2028 (USD Million)
Table 81 France: Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 82 France: Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 83 France: Cartilage Repair/Cartilage Regeneration Market, by Application, 2021-2028 (USD Million)
Table 84 France: Cartilage Repair/Cartilage Regeneration Market, by Application Site, 2021-2028 (USD Million)
9.3.5 Rest of Europe
Table 85 Rest of Europe: Cartilage Repair/Cartilage Regeneration Market, by Treatment Modality, 2021-2028 (USD Million)
Table 86 Rest of Europe: Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 87 Rest of Europe: Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 88 Rest of Europe: Cartilage Repair/Cartilage Regeneration Market, by Application, 2021-2028 (USD Million)
Table 89 Rest of Europe: Cartilage Repair/Cartilage Regeneration Market, by Application Site, 2021-2028 (USD Million)
9.4 Asia-Pacific
9.4.1 Asia-Pacific: Recession Impact
Figure 21 Asia-Pacific: Cartilage Repair/Cartilage Regeneration Market
Table 90 Asia-Pacific: Cartilage Repair/Cartilage Regeneration Market, by Country, 2021-2028 (USD Million)
Table 91 Asia-Pacific: Cartilage Repair/Cartilage Regeneration Market, by Treatment Modality, 2021-2028 (USD Million)
Table 92 Asia-Pacific: Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 93 Asia-Pacific: Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 94 Asia-Pacific: Cartilage Repair/Cartilage Regeneration Market, by Application, 2021-2028 (USD Million)
Table 95 Asia-Pacific: Cartilage Repair/Cartilage Regeneration Market, by Application Site, 2021-2028 (USD Million)
9.4.2 Japan
9.4.2.1 Japan to Hold Largest Market Share Throughout Forecast Period
Table 96 Japan: Cartilage Repair/Cartilage Regeneration Market, by Treatment Modality, 2021-2028 (USD Million)
Table 97 Japan: Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 98 Japan: Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 99 Japan: Cartilage Repair/Cartilage Regeneration Market, by Application, 2021-2028 (USD Million)
Table 100 Japan: Cartilage Repair/Cartilage Regeneration Market, by Application Site, 2021-2028 (USD Million)
9.4.3 China
9.4.3.1 China to Register Highest Growth in APAC Market
Table 101 China: Cartilage Repair/Cartilage Regeneration Market, by Treatment Modality, 2021-2028 (USD Million)
Table 102 China: Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 103 China: Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 104 China: Cartilage Repair/Cartilage Regeneration Market, by Application, 2021-2028 (USD Million)
Table 105 China: Cartilage Repair/Cartilage Regeneration Market, by Application Site, 2021-2028 (USD Million)
9.4.4 India
9.4.4.1 Rising Number of Hospitals and Developing Healthcare Infrastructure to Propel Market Growth
Table 106 India: Cartilage Repair/Cartilage Regeneration Market, by Treatment Modality, 2021-2028 (USD Million)
Table 107 India: Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 108 India: Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 109 India: Cartilage Repair/Cartilage Regeneration Market, by Application, 2021-2028 (USD Million)
Table 110 India: Cartilage Repair/Cartilage Regeneration Market, by Application Site, 2021-2028 (USD Million)
9.4.5 Rest of Asia-Pacific
Table 111 Rest of Asia-Pacific: Cartilage Repair/Cartilage Regeneration Market, by Treatment Modality, 2021-2028 (USD Million)
Table 112 Rest of Asia-Pacific: Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 113 Rest of Asia-Pacific: Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 114 Rest of Asia-Pacific: Cartilage Repair/Cartilage Regeneration Market, by Application, 2021-2028 (USD Million)
Table 115 Rest of Asia-Pacific: Cartilage Repair/Cartilage Regeneration Market, by Application Site, 2021-2028 (USD Million)
9.5 Rest of the World
9.5.1 Rest of the World: Recession Impact
Table 116 Rest of the World: Cartilage Repair/Cartilage Regeneration Market, by Treatment Modality, 2021-2028 (USD Million)
Table 117 Rest of the World: Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 118 Rest of the World: Non-Cell-based Cartilage Repair/Cartilage Regeneration Market, by Type, 2021-2028 (USD Million)
Table 119 Rest of the World: Cartilage Repair/Cartilage Regeneration Market, by Application, 2021-2028 (USD Million)
Table 120 Rest of the World: Cartilage Repair/Cartilage Regeneration Market, by Application Site, 2021-2028 (USD Million)
10 Competitive Landscape
10.1 Introduction
10.2 Revenue Analysis
Figure 22 Top Five Players Have Dominated the Market in the Last Five Years
10.3 Market Share Analysis
Figure 23 Cartilage Repair/Cartilage Regeneration Market: Market Share Analysis, 2022
Table 121 Cartilage Repair/Cartilage Regeneration Market: Degree of Competition
10.4 Company Evaluation Matrix
10.4.1 Stars
10.4.2 Emerging Leaders
10.4.3 Pervasive Players
10.4.4 Participants
Figure 24 Global Cartilage Repair/Cartilage Regeneration Market: Company Evaluation Matrix, 2022
10.5 Competitive Scenario
10.5.1 Product Approvals
Table 122 Key Product Approvals, January 2020-November 2023
10.5.2 Deals
Table 123 Key Deals, January 2020-November 2023
10.5.3 Other Developments
Table 124 Other Key Developments, January 2020-November 2023
11 Company Profiles
11.1 Key Companies
Business Overview, Products Offered, Recent Developments, and Analyst's View (Key Strengths/Right to Win, Strategic Choices Made, and Weaknesses and Competitive Threats)
11.1.1 Smith+Nephew
Table 125 Smith+Nephew: Company Overview
Figure 25 Smith+Nephew: Company Snapshot (2022)
11.1.2 Depuy Synthes (Johnson & Johnson)
Table 126 Johnson & Johnson: Company Overview
Figure 26 Johnson & Johnson: Company Snapshot (2022)
11.1.3 Zimmer Biomet Holdings, Inc.
Table 127 Zimmer Biomet Holdings, Inc.: Company Overview
Figure 27 Zimmer Biomet Holdings, Inc.: Company Snapshot (2022)
11.1.4 Stryker Corporation
Table 128 Stryker Corporation: Company Overview
Figure 28 Stryker Corporation: Company Snapshot (2022)
11.1.5 Vericel Corporation
Table 129 Vericel Corporation: Company Overview
Figure 29 Vericel Corporation: Company Snapshot (2022)
11.1.6 B. Braun Melsungen AG
Table 130 B. Braun Melsungen AG: Company Overview
Figure 30 B. Braun Melsungen AG: Company Snapshot (2022)
11.1.7 Anika Therapeutics, Inc.
Table 131 Anika Therapeutics, Inc.: Company Overview
Figure 31 Anika Therapeutics, Inc.: Company Snapshot (2022)
11.1.8 Rti Surgical
Table 132 Rti Surgical: Company Overview
11.1.9 Conmed Corporation
Table 133 Conmed Corporation.: Company Overview
Figure 32 Conmed Corporation: Company Snapshot (2022)
11.1.10 Arthrex Inc.
Table 134 Arthrex Inc.: Company Overview
11.1.11 Regrow Biosciences
Table 135 Regrow Biosciences: Company Overview
11.1.12 Medipost
Table 136 Medipost: Company Overview
Figure 33 Medipost: Company Snapshot (2022)
11.2 Other Players
11.2.1 Geistlich Pharma AG
11.2.2 Allosource
11.2.3 Orthocell Ltd.
11.2.4 Cartiheal, Inc.
11.2.5 Regentis Biomaterials
11.2.6 Lifenet Health
11.2.7 Matricel GmbH
11.2.8 Theracell Advanced Biotechnology
Details on Business Overview, Products Offered, Recent Developments, and Analyst's View (Key Strengths/Right to Win, Strategic Choices Made, and Weaknesses and Competitive Threats) Might Not be Captured in Case of Unlisted Companies