Chapter 1 Executive Summary
- Market Outlook
- Scope of Report
- Market Summary
Chapter 2 Market Overview
- Epigenetics Overview
- DNA Methylation
- Histone Modification
- RNA Modifications
- Epigenetic Modulators
Chapter 3 Market Dynamics
- Market Dynamics Snapshot
- Market Drivers
- Rising Prevalence of Cancer and Unmet Need in Oncology
- Advances in Analytical Technologies and Tools
- Increasing Investment in Biomedical Research
- Trend Towards Precision Medicine
- Growing Interest in Liquid Biopsy
- Market Restraints
- From Bench to Bedside: The Translation Gap in Epigenetics
- Epigenetic Therapeutics: Limited Clinical Success Against Solid Tumors
- Stringent Regulatory Landscape
- Market Trends
- Combining Epigenetic Modifiers with Other Therapeutic Class
- Multi-omics Integration
- Long-Read Sequencing in Epigenetic Research
- Epigenetic Biomarkers-based Blood Test for Cancer Screening
Chapter 4 Emerging Technologies and Developments
- Emerging Technologies
- Epigenome Editing
- Epitranscriptomics
- Bromodomain and Extra-Terminal Domain Inhibitors
- Menin Inhibitors
- Application Beyond Oncology
- Pipeline Analysis
- Overview
- Novel Epigenetic Therapeutics in Development in Phase 2 and Above
Chapter 5 Market Segmentation Analysis
- Segmentation Breakdown
- Epigenetics Research Tools and Reagents Market, by Study Method
- Market Overview
- Market Size and Forecast
- DNA Methylation
- Histone Modification
- RNA Modification
- In Vitro Diagnostics (IVDs) Market, by Clinical Indication
- Market Overview
- Market Size and Forecast
- Epigenetic Therapeutics Market, by Drug Class
- Market Overview
- Market Size and Forecast
- Geographic Breakdown
- Epigenetics Research Tools and Reagents Market, by Region
- Market Size and Forecast
- North America
- Europe
- Asia-Pacific
- Rest of the World
Chapter 6 Competitive Intelligence
- Research Tools and Reagents
- In Vitro Diagnostics
- Therapeutics
Chapter 7 Sustainability in the Epigenetics Market: An ESG Perspective
- Introduction to ESG
- Key ESG Issues in Epigenetics Pharmaceuticals and Diagnostics Market
- Sustainability Practices in Pharmaceuticals Manufacturing
- Sustainable Packaging
- Key ESG Issues in Epigenetics Research Tools Market
- ESG Risk Ratings Score -- Understanding the Data
- Concluding Remarks
List of Tables
Summary Table: Global Market for Epigenetics Research Tools and Reagents, IVDs and Therapeutics, by Product Type, Through 2029
Table 1: Techniques, Advantages and Disadvantages of Common DNA Methylation Analysis Methods
Table 2: Types of Noncoding (ncRNAs)
Table 3: Key Programs/Consortiums to Support Epigenetic Research
Table 4: Epigenetic Biomarker-based Blood Tests Currently Under Clinical Development
Table 5: Companies Developing Products Based on Epigenome Editing Platforms
Table 6: BET Inhibitors in Late-Stage Clinical Trials
Table 7: Menin Inhibitors in Clinical Trials
Table 8: Novel Epigenetic Therapeutic Candidates in Clinical Trials Phase 2 and Above
Table 9: Global Market for Epigenetics Research Tools and Reagents, by Study Method, Through 2029
Table 10: Commercially Available Epigenetic Biomarker-based IVDs for Colorectal Cancer
Table 11: Commercially Available Epigenetic Biomarker-based IVDs for Bladder Cancer
Table 12: Commercially Available Epigenetic Biomarker-based IVDs for Cervical Cancer
Table 13: Commercially Available Epigenetic Biomarker-based IVDs for Other Indications
Table 14: FDA Breakthrough Device Designated Epigenetic Biomarker-based Clinical Assays Currently Undergoing Clinical Validation
Table 15: Global Market for Epigenetic Biomarker-based IVDs, by Clinical Indication, Through 2029
Table 16: Commercially Available DNMT Inhibitors
Table 17: Commercially Available HDAC Inhibitors
Table 18: Commercially Available IDH Inhibitors
Table 19: Commercially Available EZH2 Inhibitors
Table 20: Global Market for Epigenetic Therapeutics, by Drug Class, Through 2029
Table 21: Global Market for Epigenetic Research Tools and Reagents, IVDs and Therapeutics, by Region, Through 2029
Table 22: North American Market for Epigenetic Research Tools and Reagents, IVDs and Therapeutics, by Product Type, Through 2029
Table 23: North American Market for Epigenetic Research Tools and Reagents, IVDs and Therapeutics, by Country, Through 2029
Table 24: European Market for Epigenetic Research Tools and Reagents, IVDs and Therapeutics, by Product Type, Through 2029
Table 25: European Market for Epigenetic Research Tools and Reagents, IVDs and Therapeutics, by Country, Through 2029
Table 26: Asia-Pacific Market for Epigenetic Research Tools and Reagents, IVDs and Therapeutics, by Product Type, Through 2029
Table 27: Asia-Pacific Market for Epigenetic Research Tools and Reagents, IVDs and Therapeutics, by Country, Through 2029
Table 28: RoW Market for Epigenetic Research Tools and Reagents, IVDs and Therapeutics, by Product Type, Through 2029
Table 29: Global Market Shares of Epigenetic Biomarkers-based IVDs, by Company, 2023
Table 30: Commercially Available Epigenetics-Targeted Drugs
Table 31: Key Sustainability Practices in the Pharmaceuticals Industry
Table 32: ESG Risk Ratings of Key Companies in the Epigenetics Market, 2024
Table 33: Ethos Impact Inc. Score Card for Key Companies in the Epigenetics Market, 2024
Table 34: Information Sources for this Report
Table 35: Abbreviations Used in the Report
Table 36: Active Motif Inc.: Company Snapshot
Table 37: Active Motif Inc.: Product Portfolio
Table 38: Active Motif Inc.: News/Key Developments, 2022
Table 39: Bio-Rad Laboratories Inc.: Company Snapshot
Table 40: Bio-Rad Laboratories Inc.: Financial Performance, FY 2022 and 2023
Table 41: Bio-Rad Laboratories Inc.: Product Portfolio
Table 42: Bio-Rad Laboratories Inc.: News/Key Developments, 2023 and 2024
Table 43: Bio-Techne: Company Snapshot
Table 44: Bio-Techne: Financial Performance, FY 2022 and 2023
Table 45: Bio-Techne: Product Portfolio
Table 46: Bio-Techne: News/Key Developments, 2023
Table 47: Bristol-Myers Squibb Co.: Company Snapshot
Table 48: Bristol-Myers Squibb Co.: Financial Performance, FY 2022 and 2023
Table 49: Bristol-Myers Squibb Co: Product Portfolio
Table 50: Daiichi Sankyo Co. Ltd.: Company Snapshot
Table 51: Daiichi Sankyo Co. Ltd.: Financial Performance, FY 2022 and 2023
Table 52: Daiichi Sankyo Co. Ltd.: Product Portfolio
Table 53: Daiichi Sankyo Co. Ltd.: News/Key Developments, 2022-2024
Table 54: Exact Sciences Corp.: Company Snapshot
Table 55: Exact Sciences Corp.: Financial Performance, FY 2022 and 2023
Table 56: Exact Sciences Corp.: Product Portfolio
Table 57: Exact Sciences Corp.: News/Key Developments, 2023 and 2024
Table 58: Guardant Health: Company Snapshot
Table 59: Guardant Health: Financial Performance, FY 2022 and 2023
Table 60: Guardant Health: Product Portfolio
Table 61: Guardant Health: News/Key Developments, 2023 and 2024
Table 62: Hologic Inc.: Company Snapshot
Table 63: Hologic Inc.: Financial Performance, FY 2023 and 2024
Table 64: Hologic Inc.: Product Portfolio
Table 65: Les Laboratoires Servier: Company Snapshot
Table 66: Les Laboratoires Servier: Financial Performance, FY 2022 and 2023
Table 67: Les Laboratoires Servier: Product Portfolio
Table 68: Les Laboratoires Servier: News/Key Developments, 2023 and 2024
Table 69: Merck KGaA: Company Snapshot
Table 70: Merck KGaA: Financial Performance, FY 2022 and 2023
Table 71: Merck KGaA: Product Portfolio
Table 72: Merck KGaA: News/Key Developments, 2023 and 2024
Table 73: Nucleix: Company Snapshot
Table 74: Nucleix: Product Portfolio
Table 75: Nucleix: News/Key Developments, 2023 and 2024
Table 76: Promega Corp.: Company Snapshot
Table 77: Promega Corp.: Product Portfolio
Table 78: Promega Corp.: News/Key Developments, 2023
Table 79: Qiagen: Company Snapshot
Table 80: Qiagen: Financial Performance, FY 2022 and 2023
Table 81: Qiagen: Product Portfolio
Table 82: Qiagen: News/Key Developments, 2023 and 2024
Table 83: Revvity Inc. (PerkinElmer): Company Snapshot
Table 84: Revvity Inc. (PerkinElmer): Financial Performance, FY 2022 and 2023
Table 85: Revvity Inc. (PerkinElmer): Product Portfolio
Table 86: Revvity Inc. (PerkinElmer): News/Key Developments, 2023
Table 87: Thermo Fisher Scientific Inc.: Company Snapshot
Table 88: Thermo Fisher Scientific Inc.: Financial Performance, FY 2022 and 2023
Table 89: Thermo Fisher Scientific Inc.: Product Portfolio
Table 90: Thermo Fisher Scientific Inc.: News/Key Developments, 2024
List of Figures
Summary Figure: Global Market Shares of Epigenetics Research Tools and Reagents, IVDs and Therapeutics, by Product Type, 2023
Figure 1: Market Dynamics of Epigenetics
Figure 2: Estimated New Cancer Cases Globally, 2022, 2045 and 2050
Figure 3: Global Blood Cancer Incidence, by Cancer Type, 2022 vs. 2045
Figure 4: PubMed Article Count: "Epigenetic," 2018-2024
Figure 5: Overcoming Barriers in the Clinical Application of Epigenetics
Figure 6: PubMed Article Count: "Epitranscriptomic" and "RNA Modification," 2021-2024
Figure 7: Trends in Clinical Trials for Epigenetic Therapeutic Agents, by Drug Class, as of December 2024
Figure 8: Global Market Shares of Epigenetics Research Tools and Reagents, by Study Method, 2023
Figure 9: Global Market Shares of Epigenetic Biomarker-based IVDs, by Clinical Indication, 2023
Figure 10: Global Market Shares of Epigenetic Therapeutics, by Drug Class, 2023
Figure 11: Global Market Shares of Epigenetic Research Tools and Reagents, IVDs and Therapeutics, by Region, 2023
Figure 12: North American Market Shares of Epigenetic Research Tools and Reagents, IVDs and Therapeutics, by Product Type, 2023
Figure 13: North American Market Shares of Epigenetic Research Tools and Reagents, IVDs and Therapeutics, by Country, 2023
Figure 14: European Market Shares of Epigenetic Research Tools and Reagents, IVDs and Therapeutics, by Product Type, 2023
Figure 15: European Market Shares of Epigenetic Research Tools and Reagents, IVDs and Therapeutics, by Country, 2023
Figure 16: Worldwide Incidence of Blood Cancer Cases, by Region, 2022
Figure 17: Asia-Pacific Market Shares of Epigenetic Research Tools and Reagents, IVDs and Therapeutics, by Product Type, 2023
Figure 18: Asia-Pacific Market Shares of Epigenetic Research Tools and Reagents, IVDs and Therapeutics, by Country, 2023
Figure 19: RoW Market Shares of Epigenetic Research Tools and Reagents, IVDs and Therapeutics, by Product Type, 2023
Figure 20: Principle Competitive Factors in Epigenetics Research Tools Market
Figure 21: Global Market Shares of Leading Manufacturers of Epigenetics-Targeted Therapeutics, 2023
Figure 22: Selected Factors Driving ESG
Figure 23: Bio-Rad Laboratories Inc.: Revenue Share, by Business Unit, FY 2023
Figure 24: Bio-Rad Laboratories Inc.: Revenue Share, by Country/Region, FY 2023
Figure 25: Bio-Techne: Revenue Share, by Business Unit, FY 2023
Figure 26: Bio-Techne: Revenue Share, by Country/Region, FY 2023
Figure 27: Bristol-Myers Squibb Co: Revenue Share, by Business Unit, FY 2023
Figure 28: Bristol-Myers Squibb Co.: Revenue Share, by Country/Region, FY 2023
Figure 29: Daiichi Sankyo Co. Ltd.: Revenue Share, by Business Unit, FY 2023
Figure 30: Daiichi Sankyo Co. Ltd.: Revenue Share, by Country/Region, FY 2023
Figure 31: Exact Sciences Corp.: Revenue Share, by Business Unit, FY 2023
Figure 32: Exact Sciences Corp.: Revenue Share, by Country/Region, FY 2023
Figure 33: Guardant Health: Revenue Share, by Business Unit, FY 2023
Figure 34: Guardant Health: Revenue Share, by Country/Region, FY 2023
Figure 35: Hologic Inc.: Revenue Share, by Business Unit, FY 2024
Figure 36: Hologic Inc.: Revenue Share, by Country/Region, FY 2024
Figure 37: Les Laboratoires Servier: Revenue Share, by Business Unit, FY 2023
Figure 38: Les Laboratoires Servier: Revenue Share, by Region, FY 2023
Figure 39: Merck KGaA: Revenue Share, by Business Unit, FY 2023
Figure 40: Merck KGaA: Revenue Share, by Country/Region, FY 2023
Figure 41: Qiagen: Revenue Share, by Business Unit, FY 2023
Figure 42: Qiagen: Revenue Share, by Country/Region, FY 2023
Figure 43: Revvity Inc. (PerkinElmer): Revenue Share, by Business Unit, FY 2023
Figure 44: Revvity Inc. (PerkinElmer): Revenue Share, by Country/Region, FY 2023
Figure 45: Thermo Fisher Scientific Inc.: Revenue Share, by Business Unit, 2023
Figure 46: Thermo Fisher Scientific Inc.: Revenue Share, by Country/Region, 2023