Hydrolase Enzymes Global Market Report 2024

The hydrolase enzymes market size has grown strongly in recent years. It will grow from $6.08 billion in 2023 to $6.54 billion in 2024 at a compound annual growth rate (CAGR) of 7.7%. The growth observed in the historical period can be attributed to several factors, including advancements in biotechnology, an increase in demand for sustainable solutions, research and development initiatives, the industrial applications of biotechnology in food processing, and an expanding role in biofuel production.

The hydrolase enzymes market size is expected to see strong growth in the next few years. It will grow to $8.86 billion in 2028 at a compound annual growth rate (CAGR) of 7.9%. The anticipated growth in the forecast period can be attributed to increased exploration in biofuel and bioenergy production, advancements in enzyme engineering, a rise in industrial biotechnology, an expanding role in personal care products, and growth in bioremediation and waste management. Major trends expected in the forecast period include exploration of microbial diversity, expanding applications in the food industry, customization through protein engineering, a focus on sustainable biocatalysis, and the development of biopharmaceuticals.

The anticipated rise in the prevalence of pancreatitis is poised to drive the growth of the hydrolase enzymes market in the foreseeable future. Pancreatitis, characterized by inflammation of the pancreas glands and severe abdominal pain, can manifest as a temporary (acute) or life-long (chronic) condition. Crucial hydrolase enzymes such as pancreatic lipase, amylase, and protease play a pivotal role in treating malabsorption associated with pancreatic insufficiency resulting from conditions such as cystic fibrosis and pancreatitis. These enzymes catalyze reactions, initiating the digestion of dietary fats. The increased incidence of acute pancreatitis in the US, ranging from 4.9 to 35 per 100,000 populations, is attributed to factors such as obesity and gallstones, as reported by UpToDate, Inc. Moreover, chronic pancreatitis leads to around 86,000 hospital stays in the US annually, according to Ada Health GmbH. Consequently, the growing prevalence of pancreatitis is a key driver behind the expansion of the hydrolase enzymes market.

The hydrolase enzymes market is also expected to witness significant growth due to the escalating demand for processed foods. Processed foods, undergoing deliberate changes through various preparation, preservation, cooking, or packaging methods, utilize hydrolase enzymes in the production of sweeteners such as high-fructose corn syrup and the breakdown of complex carbohydrates, proteins, and fats into simpler forms. The Agricultural and Processed Food Products Export Development Authority (APEDA) reported a notable increase in processed food product exports from $11,671 million to $13,261 million in 2021-22, highlighting the rising demand for processed foods. This surge in demand is a key factor propelling the growth of the hydrolase enzymes market.

A prominent trend is the focus on product innovations by major industry players. Companies are introducing innovative products to sustain their market positions, as demonstrated by Biocatalysts Ltd., a UK-based biotechnology company. Biocatalysts introduced Promod™ 517MDP, an enzyme specifically targeting dairy protein, with a high degree of hydrolysis of casein protein (>40%). This innovative enzyme is employed in the production of foods for special medical purposes, enhancing solubility and digestibility.

Major companies operating in the hydrolase enzymes market are actively launching new products to maintain their competitive edge. In December 2021, BASF SE, a Germany-based chemicals company, introduced Natupulse TS, a non-starch polysaccharide (NSP) enzyme containing mannanase. Natupulse TS degrades NSPs such as mannans, improving nutrient digestion and ensuring more sustainable production for animal feed. This enzyme is available in both powder and liquid forms, offering overall stability during storage and in challenging conditions during the pelleting process.

In May 2021, BRAIN AG, a Germany-based biotechnology company, acquired Biocatalysts Ltd. for $5.51 million (GBP 3.9 million). This acquisition aims to strengthen BRAIN AG's bio-industrial segment and broaden commercial opportunities through Biocatalyst's portfolio and technology. Biocatalysts Ltd., a UK-based enzyme manufacturer, plays a significant role in this strategic move.

Major companies operating in the hydrolase enzymes market report are Creative Enzymes Holdings Limited, Advanced Enzyme Technologies Limited, Specialty Enzymes & Probiotics, Novozymes A/S, Antozyme Biotech Private Limited, Infinita Biotech Private Limited, Aumgene Biosciences (Shanghai) Co. Ltd., AB Enzymes GmbH, Dyadic International Inc., Sisco Research Laboratories Pvt Ltd., Amano Enzyme Inc., Codexis Inc., Merck KGaA, BESTZYME BIO-ENGINEERING CO. Ltd., Bioseutica Group, BASF SE, Royal DSM NV, Kemin Industries Inc., Epygen Labs FZ LLC, DuPont de Nemours Inc., Biovet Private Limited, Enzyme Development Corporation, Associated British Foods, Chr. Hansen Holding A/S, Genencor International Inc., F. Hoffmann-La Roche Ltd., Thermo Fisher Scientific Inc., Koninklijke DSM N.V., Enzymes Biotec Limited, Kerry Group plc, Danisco A/S.

North America was the largest region in the hydrolase enzymes market in 2023. Europe is expected to be the fastest-growing region in the hydrolase enzymes market report during the forecast period. The regions covered in the hydrolase enzymes market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the hydrolase enzymes market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The primary types of hydrolase enzymes include esterase, glycosylases, peptidases, and others. Esterase, for instance, is an enzyme that expedites the hydrolysis or synthesis of esters. It is applied in clinical pharmacotherapy, drug prodrug activation, and the detoxification of active compounds. Various bonds targeted by hydrolase enzymes include ester bonds (esterases), sugars (DNA glycosylases and glycoside hydrolase), ether bonds (thioether and trialkyl sulfonium), peptide bonds (peptidases), carbon-nitrogen bonds (excluding peptide bonds), acid anhydrides, carbon-carbon bonds, halide bonds, phosphorus-nitrogen bonds, and others. These enzymes are employed across diverse applications such as pharmaceuticals, food and beverages, laundry detergents, cosmetics, textiles, pulp and paper, biofuels, and more.

The hydrolase enzymes market research report is one of a series of new reports that provides hydrolase enzymes market statistics, including the hydrolase enzymes industry global market size, regional shares, competitors with a hydrolase enzymes market share, detailed hydrolase enzymes market segments, market trends and opportunities, and any further data you may need to thrive in the hydrolase enzymes industry. This hydrolase enzymes market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.


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