Hydrolase Enzymes Market Report 2025

The hydrolase enzymes market size has grown strongly in recent years. It will grow from $6.47 billion in 2024 to $6.96 billion in 2025 at a compound annual growth rate (CAGR) of 7.6%. The growth in the historic period can be attributed to advancements in biotechnology, rise in demand for sustainable solutions, research and development initiatives, industrial applications in food processing, expanding role in biofuel production.

The hydrolase enzymes market size is expected to see strong growth in the next few years. It will grow to $9.56 billion in 2029 at a compound annual growth rate (CAGR) of 8.3%. The growth in the forecast period can be attributed to exploration in biofuel and bioenergy production, advancements in enzyme engineering, rise in industrial biotechnology, growing role in personal care products, expansion in bioremediation and waste management. Major trends in the forecast period include microbial diversity exploration, application expansion in food industry, customization through protein engineering, focus on sustainable biocatalysis, biopharmaceuticals development.

The increasing prevalence of pancreatitis is projected to drive the growth of the hydrolase enzymes market in the coming years. Pancreatitis is characterized by inflammation of the pancreas, leading to severe abdominal pain. While it is typically a temporary (acute) condition, it can also manifest as a chronic issue. Essential hydrolase enzymes, such as pancreatic lipase, amylase, and protease, are utilized to treat malabsorption related to pancreatic insufficiency caused by conditions like cystic fibrosis and pancreatitis. These enzymes facilitate the reaction of triacylglycerol with water, producing diacylglycerol and a fatty acid anion, thereby initiating the digestion of dietary fats and addressing pancreatic exocrine insufficiency. For example, in December 2022, UpToDate, Inc., a US-based subscription service providing current clinical information to physicians, reported that the annual incidence of acute pancreatitis in the US ranges from 4.9 to 35 cases per 100,000 individuals, largely due to rising rates of obesity and gallstones. Consequently, the increasing prevalence of pancreatitis is propelling the growth of the hydrolase enzymes market.

The rising demand for processed foods is expected to further stimulate growth in the hydrolase enzymes market. Processed foods are items that undergo intentional modifications to their natural state through various preparation, preservation, cooking, or packaging methods. Hydrolase enzymes are employed in processed foods to produce various sweeteners, such as high-fructose corn syrup, and to break down complex carbohydrates, proteins, and fats into simpler forms. For instance, in May 2024, the United States Department of Agriculture, a US-based federal agency, reported that in 2023, the value of U.S. processed food exports rose by 0.2% year-over-year to reach $14.73 billion, marking a record for the third consecutive year. Thus, the increasing demand for processed foods is driving the growth of the hydrolase enzymes market.

Product innovations are becoming a significant trend in the hydrolase enzyme markets. Leading companies in the hydrolase enzymes sector are launching innovative products to maintain their market position. For example, Biocatalysts Ltd., a UK-based biotechnology firm specializing in specialty enzymes, introduced Promod 517MDP (P517MDP), an enzyme specifically designed for dairy proteins. P517MDP is a highly effective exopeptidase that hydrolyzes casein protein by over 40% into smaller components, such as peptides and amino acids, which can be utilized in the production of foods for special medical purposes (FSMP*), including specialized infant formulas. This enzyme enhances solubility and improves digestibility.

Key players in the hydrolase enzymes market are concentrating on innovations like advanced enzyme engineering to boost the efficiency and sustainability of industrial processes, including plastic recycling and bio-based product manufacturing. Enzymatic recycling employs naturally occurring enzymes to decompose plastics, such as PET, into their fundamental components, enabling reprocessing into new materials without compromising quality. For instance, in August 2023, Carbios, a biotech company based in France, launched a groundbreaking enzymatic recycling process that represents a significant advancement in managing PET (polyethylene terephthalate) waste. This innovative method converts waste into recycled and recyclable products while maintaining quality, using naturally occurring enzymes to transform plastic and textile waste into new materials.

In December 2023, Kerry Group plc, an Ireland-based food product manufacturer, acquired Chr Hansen Holding A/S for an undisclosed amount. This acquisition aims to enhance Kerry Group's biotechnology solutions capabilities by broadening its portfolio of lactase enzymes, thereby addressing the increasing global demand for lactose-free dairy products and strengthening its position in the functional ingredients market. Chr. Hansen Holding A/S is a bioscience company based in Denmark that produces hydrolase enzymes.

Major companies operating in the hydrolase enzymes market include Creative Enzymes Holdings Limited, Advanced Enzyme Technologies Limited, Specialty Enzymes & Probiotics, Novozymes A/S, Antozyme Biotech Private Limited, Infinita Biotech Private Limited, Aumgene Biosciences (Shanghai) Co. Ltd., AB Enzymes GmbH, Dyadic International Inc., Sisco Research Laboratories Pvt Ltd., Amano Enzyme Inc., Codexis Inc., Merck KGaA, BESTZYME BIO-ENGINEERING CO. Ltd., Bioseutica Group, BASF SE, Kemin Industries Inc., Epygen Labs FZ LLC, DuPont de Nemours Inc., Biovet Private Limited, Enzyme Development Corporation, Associated British Foods, Chr. Hansen Holding A/S, Thermo Fisher Scientific Inc., Koninklijke DSM N.V., Enzymes Biotec Limited, Kerry Group plc.

North America was the largest region in the hydrolase enzymes market in 2024. Europe is expected to be the fastest-growing region in the hydrolase enzymes market report during the forecast period. The regions covered in the hydrolase enzymes market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the hydrolase enzymes market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Hydrolase enzymes represent a type of enzyme that acts as a biochemical catalyst, facilitating the breaking of a chemical bond through the introduction of water, leading to the division of larger molecules into smaller ones. These enzymes find widespread use in biochemical processes, including substrate breakdown, the degradation of toxins, and the synthesis of biopolymers.

The primary types of hydrolase enzymes include esterase, glycosylases, peptidases, and others. Esterase, for instance, is an enzyme that expedites the hydrolysis or synthesis of esters. It is applied in clinical pharmacotherapy, drug prodrug activation, and the detoxification of active compounds. Various bonds targeted by hydrolase enzymes include ester bonds (esterases), sugars (DNA glycosylases and glycoside hydrolase), ether bonds (thioether and trialkyl sulfonium), peptide bonds (peptidases), carbon-nitrogen bonds (excluding peptide bonds), acid anhydrides, carbon-carbon bonds, halide bonds, phosphorus-nitrogen bonds, and others. These enzymes are employed across diverse applications such as pharmaceuticals, food and beverages, laundry detergents, cosmetics, textiles, pulp and paper, biofuels, and more.

The hydrolase enzymes market research report is one of a series of new reports that provides hydrolase enzymes market statistics, including the hydrolase enzymes industry global market size, regional shares, competitors with a hydrolase enzymes market share, detailed hydrolase enzymes market segments, market trends and opportunities, and any further data you may need to thrive in the hydrolase enzymes industry. This hydrolase enzymes market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The hydrolase enzymes market consists of sales of lipases, proteases, epoxide, hydrolases, and nitrile hydrolases. Values in this market are ‘factory gate’ values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

This product will be delivered within 3-5 business days.