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Natural Killer Cells Therapeutics Market Report by Therapeutics, Application, End User, and Region 2024-2032

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    Report

  • 140 Pages
  • August 2024
  • Region: Global
  • IMARC Group
  • ID: 5912139
The global natural killer cells therapeutics market size reached US$ 2.8 Billion in 2023. Looking forward, the publisher expects the market to reach US$ 8.3 Billion by 2032, exhibiting a growth rate (CAGR) of 12.83% during 2023-2032. The rising risks of developing cancer, along with the expanding geriatric population, are propelling the market.

Natural Killer Cells Therapeutics Market Analysis:

  • Major Market Drivers: The growing number of individuals with cancer, infectious diseases, and liver disorders, on account of the lack of physical activities, unhealthy dietary patterns, and the increasing air pollution levels, is catalyzing the market.
  • Key Market Trends: Extensive investments in clinical studies that focus on tumor-targeted antibody strategies to minimize risks and toxicities are among the emerging trends fueling the market.
  • Competitive Landscape: Some of the prominent companies in the global market include Affimed GmbH, Bristol-Myers Squibb Company, Fate Therapeutics, Fortress Biotech Inc., Glycostem Therapeutics, Innate Pharma S.A., Kuur Therapeutics Inc. (Athenex Inc.), Nkarta Inc., Takeda Pharmaceutical Company Limited, and Ziopharm Oncology Inc., among many others.
  • Geographical Trends: North America exhibits a clear dominance in the market, owing to numerous financial schemes by government agencies across the region for cancer patients.
  • Challenges and Opportunities: One of the challenges hindering the market is the difficulty in manufacturing processes. This can be overcome by improving scalable production methods to ensure quality and efficacy.

Natural Killer Cells Therapeutics Market Trends:

Increasing Popularity of Combination Therapies

Combining NK cell therapies with other treatment modalities to enhance therapeutic efficacy is gaining extensive traction. For example, Innate Pharma's Lumoxiti, an anti-CD22 immunotoxin, is adopted in conjunction with NK cells to destroy and target CD22-expressing cancer cells in hairy cell leukemia. Moreover, this approach leverages the strengths of both therapies. Besides this, in May 2024, Coeptis Therapeutics Holdings, Inc., a biopharmaceutical company developing innovative cell therapy platforms for autoimmune, cancer, and infectious diseases, introduced SNAP-CAR NK cells to target multiple antigens.

Growing Regulatory Approval

The rising focus among government agencies on enhancing the reliability and efficiency of NK cell production is acting as a significant growth-inducing factor. Furthermore, they are encouraging the translation of laboratory research into viable clinical therapies, which will continue to fuel the market over the foreseeable future. For example, in April 2024, Ingenium Therapeutics, a leading innovator in next-generation NK cell therapies, received an Orphan Drug Designation from the U.S. Food and Drug Administration (FDA) for the treatment of acute myeloid leukemia (AML).

Rising Demand for Real-Time Monitoring

The widespread integration of real-time monitoring and data analytics into NK cell therapy development is enhancing treatment precision and patient outcomes. Moreover, platforms like Bio-Techne's Ella system enable precise monitoring of cytokine production during NK cell expansion, thereby ensuring optimal cell functionality. Real-time analytics also allow researchers to adjust culture conditions dynamically, which aids in improving the quality and effectiveness of the NK cells produced. This is positively influencing the market.

Global Natural Killer Cells Therapeutics Industry Segmentation:

The publisher provides an analysis of the key trends in each segment of the market, along with the natural killer cells therapeutics market forecast at the global, regional, and country levels for 2024-2032. Our report has categorized the market based on therapeutics, application, and end user.

Breakup by Therapeutics:

  • NK Cell Therapies
  • NK Cell Directed Antibodies

Currently, NK cell directed antibodies hold the majority of the total market share


NK cell directed antibodies target natural killer cells to enhance their ability to recognize and destroy cancer cells. For example, Affimed's AFM13, a bispecific NK cell engager, targets CD30 on cancer cells and CD16A on NK cells.

Breakup by Application:

  • Cancer
  • Gastrointestinal Diseases
  • Immunoproliferative Disorders
  • Others

Cancer currently exhibits a clear dominance in the market


The inflating need for effective cancer treatments drives the segment's growth. Recent product launches have underscored the potential of NK cell-based therapies in oncology. For instance, Fate Therapeutics' FT596 is an off-the-shelf, iPSC-derived NK cell therapy designed to target multiple cancer types, including B-cell malignancies.

Breakup by End User:

  • Hospitals
  • Research Centers and Institutes
  • Others

Currently, research centers and institutes hold the majority of the total market share


Research centers and institutes offer high-quality reagents and technologies that streamline NK cell research, which is increasing the natural killer cells therapeutics market share. For example, Bio-Techne's Cloudz Human NK Cell Expansion Kit allows researchers to expand NK cells ex vivo efficiently.

Breakup by Region:

  • North America
  • United States
  • Canada
  • Asia-Pacific
  • China
  • Japan
  • India
  • South Korea
  • Australia
  • Indonesia
  • Others
  • Europe
  • Germany
  • France
  • United Kingdom
  • Italy
  • Spain
  • Russia
  • Others
  • Latin America
  • Brazil
  • Mexico
  • Others
  • Middle East and Africa

North America exhibits a clear dominance in the market


Advancements in biotechnology and a strong focus on innovative cancer treatments are primarily catalyzing the market in North America. According to the publisher, the United States cancer immunotherapy market size is projected to exhibit a growth rate (CAGR) of 10.90% during 2024-2032. Besides this, collaborations between biotech firms are strengthening the regional market.

Competitive Landscape:

The market research report has provided a comprehensive analysis of the competitive landscape. Detailed profiles of all major market companies have also been provided. Some of the key players in the market include:
  • Affimed GmbH
  • Bristol-Myers Squibb Company
  • Fate Therapeutics
  • Fortress Biotech Inc.
  • Glycostem Therapeutics
  • Innate Pharma S.A.
  • Kuur Therapeutics Inc. (Athenex Inc.)
  • Nkarta Inc.
  • Takeda Pharmaceutical Company Limited
  • Ziopharm Oncology Inc.
(Please note that this is only a partial list of the key players, and the complete list is provided in the report.)

Natural Killer Cells Therapeutics Market Recent Developments:
  • May 2024: Coeptis Therapeutics Holdings, Inc., a biopharmaceutical company developing innovative cell therapy platforms for autoimmune, cancer, and infectious diseases, introduced SNAP-CAR NK cells to target multiple antigens.
  • April 2024: Ingenium Therapeutics, a leading innovator in next-generation NK cell therapies, received an Orphan Drug Designation from the U.S. Food and Drug Administration (FDA) for the treatment of acute myeloid leukemia (AML).
  • January 2024: Indapta Therapeutics, Inc., a privately held biotechnology company developing IDP-023, a natural killer (NK) cell therapeutics for the treatment of cancer, announced the treatment of the first patients in its Phase 1 trial in multiple myeloma and non-Hodgkin’s lymphoma.

Key Questions Answered in This Report

1. What was the size of the global natural killer cells therapeutics market in 2023?
2. What is the expected growth rate of the global natural killer cells therapeutics market during 2024-2032?
3. What are the key factors driving the global natural killer cells therapeutics market?
4. What has been the impact of COVID-19 on the global natural killer cells therapeutics market?
5. What is the breakup of the global natural killer cells therapeutics market based on the therapeutics?
6. What is the breakup of the global natural killer cells therapeutics market based on the application?
7. What is the breakup of the global natural killer cells therapeutics market based on the end user?
8. What are the key regions in the global natural killer cells therapeutics market?
9. Who are the key players/companies in the global natural killer cells therapeutics market?

Table of Contents

1 Preface
2 Scope and Methodology
2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
2.3.1 Primary Sources
2.3.2 Secondary Sources
2.4 Market Estimation
2.4.1 Bottom-Up Approach
2.4.2 Top-Down Approach
2.5 Forecasting Methodology
3 Executive Summary
4 Introduction
4.1 Overview
4.2 Key Industry Trends
5 Global Natural Killer Cells Therapeutics Market
5.1 Market Overview
5.2 Market Performance
5.3 Impact of COVID-19
5.4 Market Forecast
6 Market Breakup by Therapeutics
6.1 NK Cell Therapies
6.1.1 Market Trends
6.1.2 Market Forecast
6.2 NK Cell Directed Antibodies
6.2.1 Market Trends
6.2.2 Market Forecast
7 Market Breakup by Application
7.1 Cancer
7.1.1 Market Trends
7.1.2 Market Forecast
7.2 Gastrointestinal Diseases
7.2.1 Market Trends
7.2.2 Market Forecast
7.3 Immunoproliferative Disorders
7.3.1 Market Trends
7.3.2 Market Forecast
7.4 Others
7.4.1 Market Trends
7.4.2 Market Forecast
8 Market Breakup by End User
8.1 Hospitals
8.1.1 Market Trends
8.1.2 Market Forecast
8.2 Research Centers and Institutes
8.2.1 Market Trends
8.2.2 Market Forecast
8.3 Others
8.3.1 Market Trends
8.3.2 Market Forecast
9 Market Breakup by Region
9.1 North America
9.1.1 United States
9.1.1.1 Market Trends
9.1.1.2 Market Forecast
9.1.2 Canada
9.1.2.1 Market Trends
9.1.2.2 Market Forecast
9.2 Asia-Pacific
9.2.1 China
9.2.1.1 Market Trends
9.2.1.2 Market Forecast
9.2.2 Japan
9.2.2.1 Market Trends
9.2.2.2 Market Forecast
9.2.3 India
9.2.3.1 Market Trends
9.2.3.2 Market Forecast
9.2.4 South Korea
9.2.4.1 Market Trends
9.2.4.2 Market Forecast
9.2.5 Australia
9.2.5.1 Market Trends
9.2.5.2 Market Forecast
9.2.6 Indonesia
9.2.6.1 Market Trends
9.2.6.2 Market Forecast
9.2.7 Others
9.2.7.1 Market Trends
9.2.7.2 Market Forecast
9.3 Europe
9.3.1 Germany
9.3.1.1 Market Trends
9.3.1.2 Market Forecast
9.3.2 France
9.3.2.1 Market Trends
9.3.2.2 Market Forecast
9.3.3 United Kingdom
9.3.3.1 Market Trends
9.3.3.2 Market Forecast
9.3.4 Italy
9.3.4.1 Market Trends
9.3.4.2 Market Forecast
9.3.5 Spain
9.3.5.1 Market Trends
9.3.5.2 Market Forecast
9.3.6 Russia
9.3.6.1 Market Trends
9.3.6.2 Market Forecast
9.3.7 Others
9.3.7.1 Market Trends
9.3.7.2 Market Forecast
9.4 Latin America
9.4.1 Brazil
9.4.1.1 Market Trends
9.4.1.2 Market Forecast
9.4.2 Mexico
9.4.2.1 Market Trends
9.4.2.2 Market Forecast
9.4.3 Others
9.4.3.1 Market Trends
9.4.3.2 Market Forecast
9.5 Middle East and Africa
9.5.1 Market Trends
9.5.2 Market Breakup by Country
9.5.3 Market Forecast
10 SWOT Analysis
10.1 Overview
10.2 Strengths
10.3 Weaknesses
10.4 Opportunities
10.5 Threats
11 Value Chain Analysis
12 Porters Five Forces Analysis
12.1 Overview
12.2 Bargaining Power of Buyers
12.3 Bargaining Power of Suppliers
12.4 Degree of Competition
12.5 Threat of New Entrants
12.6 Threat of Substitutes
13 Price Analysis
14 Competitive Landscape
14.1 Market Structure
14.2 Key Players
14.3 Profiles of Key Players
14.3.1 Affimed GmbH
14.3.1.1 Company Overview
14.3.1.2 Product Portfolio
14.3.1.3 Financials
14.3.2 Bristol-Myers Squibb Company
14.3.2.1 Company Overview
14.3.2.2 Product Portfolio
14.3.2.3 Financials
14.3.2.4 SWOT Analysis
14.3.3 Fate Therapeutics
14.3.3.1 Company Overview
14.3.3.2 Product Portfolio
14.3.3.3 Financials
14.3.4 Fortress Biotech Inc.
14.3.4.1 Company Overview
14.3.4.2 Product Portfolio
14.3.4.3 Financials
14.3.5 Glycostem Therapeutics
14.3.5.1 Company Overview
14.3.5.2 Product Portfolio
14.3.6 Innate Pharma S.A.
14.3.6.1 Company Overview
14.3.6.2 Product Portfolio
14.3.6.3 Financials
14.3.7 Kuur Therapeutics Inc. (Athenex Inc.)
14.3.7.1 Company Overview
14.3.7.2 Product Portfolio
14.3.8 Nkarta Inc.
14.3.8.1 Company Overview
14.3.8.2 Product Portfolio
14.3.8.3 Financials
14.3.9 Takeda Pharmaceutical Company Limited
14.3.9.1 Company Overview
14.3.9.2 Product Portfolio
14.3.9.3 Financials
14.3.9.4 SWOT Analysis
14.3.10 Ziopharm Oncology Inc.
14.3.10.1 Company Overview
14.3.10.2 Product Portfolio
14.3.10.3 Financials
List of Figures
Figure 1: Global: Natural Killer Cells Therapeutics Market: Major Drivers and Challenges
Figure 2: Global: Natural Killer Cells Therapeutics Market: Sales Value (in Billion US$), 2018-2023
Figure 3: Global: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Billion US$), 2024-2032
Figure 4: Global: Natural Killer Cells Therapeutics Market: Breakup by Therapeutics (in %), 2023
Figure 5: Global: Natural Killer Cells Therapeutics Market: Breakup by Application (in %), 2023
Figure 6: Global: Natural Killer Cells Therapeutics Market: Breakup by End User (in %), 2023
Figure 7: Global: Natural Killer Cells Therapeutics Market: Breakup by Region (in %), 2023
Figure 8: Global: Natural Killer Cells Therapeutics (NK Cell Therapies) Market: Sales Value (in Million US$), 2018 & 2023
Figure 9: Global: Natural Killer Cells Therapeutics (NK Cell Therapies) Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 10: Global: Natural Killer Cells Therapeutics (NK Cell Directed Antibodies) Market: Sales Value (in Million US$), 2018 & 2023
Figure 11: Global: Natural Killer Cells Therapeutics (NK Cell Directed Antibodies) Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 12: Global: Natural Killer Cells Therapeutics (Cancer) Market: Sales Value (in Million US$), 2018 & 2023
Figure 13: Global: Natural Killer Cells Therapeutics (Cancer) Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 14: Global: Natural Killer Cells Therapeutics (Gastrointestinal Diseases) Market: Sales Value (in Million US$), 2018 & 2023
Figure 15: Global: Natural Killer Cells Therapeutics (Gastrointestinal Diseases) Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 16: Global: Natural Killer Cells Therapeutics (Immunoproliferative Disorders) Market: Sales Value (in Million US$), 2018 & 2023
Figure 17: Global: Natural Killer Cells Therapeutics (Immunoproliferative Disorders) Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 18: Global: Natural Killer Cells Therapeutics (Other Applications) Market: Sales Value (in Million US$), 2018 & 2023
Figure 19: Global: Natural Killer Cells Therapeutics (Other Applications) Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 20: Global: Natural Killer Cells Therapeutics (Hospitals) Market: Sales Value (in Million US$), 2018 & 2023
Figure 21: Global: Natural Killer Cells Therapeutics (Hospitals) Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 22: Global: Natural Killer Cells Therapeutics (Research Centers and Institutes ) Market: Sales Value (in Million US$), 2018 & 2023
Figure 23: Global: Natural Killer Cells Therapeutics (Research Centers and Institutes ) Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 24: Global: Natural Killer Cells Therapeutics (Other End Users) Market: Sales Value (in Million US$), 2018 & 2023
Figure 25: Global: Natural Killer Cells Therapeutics (Other End Users) Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 26: North America: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 27: North America: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 28: United States: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 29: United States: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 30: Canada: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 31: Canada: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 32: Asia-Pacific: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 33: Asia-Pacific: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 34: China: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 35: China: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 36: Japan: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 37: Japan: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 38: India: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 39: India: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 40: South Korea: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 41: South Korea: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 42: Australia: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 43: Australia: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 44: Indonesia: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 45: Indonesia: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 46: Others: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 47: Others: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 48: Europe: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 49: Europe: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 50: Germany: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 51: Germany: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 52: France: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 53: France: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 54: United Kingdom: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 55: United Kingdom: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 56: Italy: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 57: Italy: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 58: Spain: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 59: Spain: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 60: Russia: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 61: Russia: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 62: Others: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 63: Others: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 64: Latin America: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 65: Latin America: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 66: Brazil: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 67: Brazil: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 68: Mexico: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 69: Mexico: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 70: Others: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 71: Others: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 72: Middle East and Africa: Natural Killer Cells Therapeutics Market: Sales Value (in Million US$), 2018 & 2023
Figure 73: Middle East and Africa: Natural Killer Cells Therapeutics Market: Breakup by Country (in %), 2023
Figure 74: Middle East and Africa: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million US$), 2024-2032
Figure 75: Global: Natural Killer Cells Therapeutics Industry: SWOT Analysis
Figure 76: Global: Natural Killer Cells Therapeutics Industry: Value Chain Analysis
Figure 77: Global: Natural Killer Cells Therapeutics Industry: Porter's Five Forces Analysis
List of Tables
Table 1: Global: Natural Killer Cells Therapeutics Market: Key Industry Highlights, 2023 and 2032
Table 2: Global: Natural Killer Cells Therapeutics Market Forecast: Breakup by Therapeutics (in Million US$), 2024-2032
Table 3: Global: Natural Killer Cells Therapeutics Market Forecast: Breakup by Application (in Million US$), 2024-2032
Table 4: Global: Natural Killer Cells Therapeutics Market Forecast: Breakup by End User (in Million US$), 2024-2032
Table 5: Global: Natural Killer Cells Therapeutics Market Forecast: Breakup by Region (in Million US$), 2024-2032
Table 6: Global: Natural Killer Cells Therapeutics Market: Competitive Structure
Table 7: Global: Natural Killer Cells Therapeutics Market: Key Players

Companies Mentioned

  • Affimed GmbH
  • Bristol-Myers Squibb Company
  • Fate Therapeutics
  • Fortress Biotech Inc.
  • Glycostem Therapeutics
  • Innate Pharma S.A.
  • Kuur Therapeutics Inc. (Athenex Inc.)
  • Nkarta Inc.
  • Takeda Pharmaceutical Company Limited
  • Ziopharm Oncology Inc.

Methodology

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Table Information