The global orthopedic growth factor market was valued at $1.05 billion in 2024 and is projected to grow at a CAGR of 2.2%, reaching $1.2 billion by 2031.
This market is segmented by indication type, including:
- Cervical Disc Degeneration
- Tibial Fractures
- Spine
- Ankle & Hindfoot Fusion
Market Insights & Data Coverage
- Unit Sales & Average Selling Prices
- Market Size & Growth Trends
- Procedure Numbers
- Market Drivers & Limiters
- Market Forecasts Until 2031
- Historical Data (2021-2023)
- Competitive Landscape, Mergers & Acquisitions
- Company Profiles & Product Portfolios
Market Trends
- Impact of COVID-19 on Market Growth:
- The COVID-19 pandemic led to a decline in sales due to canceled elective surgeries in 2020.
- Despite this temporary disruption, the market recovered strongly by 2022 and returned to steady growth.
- Continued Demand for Spinal Fusion Therapies:
- Spinal fusion remains a key driver of growth for orthopedic growth factors.
- Ongoing clinical research supports the efficacy of growth factors in bone healing and spinal procedures.
- Regulatory Approvals Expanding Market Reach:
- Companies are securing FDA approvals for expanded indications, leading to wider adoption of orthopedic growth factors.
- Recent approvals have fueled growth in the cervical disc degeneration and hindfoot/ankle fusion segments.
Market Share Insights
Top Competitors in the Global Orthopedic Growth Factor Market (2024):1 Medtronic
- Market leader in the orthopedic growth factor segment.
- INFUSE® remains the gold standard for spinal fusion therapies.
2 Cerapedics
- Second-largest market share with its i-Factor™ product.
- Expanded FDA approval allows i-Factor™ to be used in single-level anterior cervical discectomy fusion (ACDF) with an allograft bone ring or fusion interbody device.
3 Stryker
- Third-largest competitor, known for its AUGMENT® product line.
- AUGMENT® is the first and only FDA-approved alternative to autograft for hindfoot and ankle arthrodesis.
Market Segmentation Summary
Cervical Disc Degeneration Market
- Growth factors aiding in cervical spine fusion procedures.
Tibial Fracture Market
- Orthopedic growth factors used in tibial fracture repair and bone healing.
Spine Market
- Key segment driven by spinal fusion procedures.
Ankle & Hindfoot Fusion Market
- Focus on bone regeneration and fusion techniques for foot and ankle disorders.
Global Research Scope
- Regions Covered:
- North America (U.S., Canada)
- Latin America (Brazil, Mexico, Argentina, Colombia, Chile)
- Western Europe (Germany, France, U.K., Spain, Italy)
- Central & Eastern Europe (Poland, Russia, Turkey, Hungary)
- Middle East (Saudi Arabia, UAE, Israel)
- Asia Pacific (China, Japan, India, South Korea, Australia)
- Africa (South Africa, Egypt, Nigeria, Kenya)
- Base Year: 2024
- Forecast Period: 2025-2031
- Historical Data: 2021-2023
Quantitative Coverage
- Market Size, Market Shares
- Market Forecasts, Growth Rates
- Units Sold, Average Selling Prices
- Procedure Numbers
Qualitative Coverage
- COVID-19 Impact
- Market Growth Trends & Limiters
- Competitive Analysis & SWOT for Top Competitors
- Mergers & Acquisitions
- Company Profiles & Product Portfolios
- FDA Recalls, Disruptive Technologies
- Disease Overviews
Data Sources:
- Primary Interviews with Industry Leaders
- Government Physician Data & Regulatory Data
- Hospital Private Data
- Import & Export Data
- Internal Database
Table of Contents
- Executive Summary
- Global Orthopedic Growth Factor Market Overview
- Competitive Analysis
- Procedure Segmentation
- Market Segmentation
- Regions Included
- Introduction
- Procedure Numbers
- Market Analysis and Forecast
- Unit Analysis
- Cervical Disc Degeneration Growth Factor Units Sold
- Tibial Fracture Orthopedic Growth Factor Units Sold
- Spine Orthopedic Growth Factor Units Sold
- Ankle & Hindfoot Fusion Growth Factor Units Sold
- Drivers and Limiters
- Market Drivers
- Market Limiters
- Competitive Market Share Analysis
- Orthopedic Growth Factor Market, Global, 2024 & 2031
- Orthopedic Growth Factor Procedures, Global, 2024
- Orthopedic Growth Factor Procedures by Segment, Global, 2021 - 2031
- Orthopedic Growth Factor Device Market, Global, 2021 - 2031
- Leading Competitors, Orthopedic Growth Factor Market, Global, 2024
- Orthopedic Growth Factor Procedure Segmentation
- Orthopedic Growth Factor Market Segmentation
- Orthopedic Growth Factor Regions Covered, Global
- Orthopedic Growth Factor Procedures by Region, Global, 2024 - 2031
- Orthopedic Growth Factor Procedures by Country, North America, 2021 - 2031
- Orthopedic Growth Factor Procedures by Country, Latin America, 2021 - 2031
- Orthopedic Growth Factor Procedures by Country, Western Europe, 2021 - 2031
- Orthopedic Growth Factor Procedures by Country, Central & Eastern Europe, 2021 - 2031
- Orthopedic Growth Factor Procedures by Country, Middle East, 2021 - 2031
- Orthopedic Growth Factor Procedures by Country, Asia-Pacific, 2021 - 2031
- Orthopedic Growth Factor Procedures by Country, Africa, 2021 - 2031
- Orthopedic Growth Factor Market, Global, 2021 - 2031
- Units Sold by Region, Orthopedic Growth Factor Market, Global, 2021 - 2031
- Average Selling Price by Region, Orthopedic Growth Factor Market, Global, 2021 - 2031 (US$)
- Market Value by Region, Orthopedic Growth Factor Market, Global, 2021 - 2031 (US$M)
- Cervical Disc Degeneration Growth Factor Units Sold by Region, Global, 2021 - 2031
- Tibial Fracture Growth Factor Units Sold by Region, Global, 2021 - 2031
- Spine Growth Factor Units Sold by Region, Global, 2021 - 2031
- Ankle & Hindfoot Fusion Growth Factor Units Sold by Region, Global, 2021 - 2031
- Leading Competitors, Orthopedic Growth Factor Market, Global, 2024
Companies Mentioned (Partial List)
A selection of companies mentioned in this report includes, but is not limited to:
- AbbVie
- LCA Pharma
- Acumed
- LifeLink Tissue Bank
- AlloSource
- LifeNet Health
- Alphatec Spine
- Meda Pharma
- Anika Therapeutics
- Medtronic
- Arthrex
- MTF
- B. Braun Melsungen
- Novabone
- Baxter
- Nuo Therapeutics
- Berkeley Advanced Biomaterials
- Octane Medical
- Biocell
- Orthocell Ltd.
- Biocomposites
- OrthogenRx
- Biogennix
- Orthofix
- Bioiberica
- Osteogenics
- Biomatlante
- OsteoMed
- Biotissue Technologies
- Paragon 28
- Bioventus
- Plasmaconcept
- Bonalive
- PromoCell
- Celling Biosciences
- Rebone Biomaterials
- Cerapedics
- Recordati
- Cingal
- Regenexx
- Croma-Pharma
- Regenity Biosciences
- CO.DON GmbH
- RTI Surgical
- CONMED
- Sanofi
- Curasan
- Sartorius CellGenix GmbH
- DCI Donor Services
- Seikagaku
- DePuy Synthes
- Smith & Nephew
- Documedica
- Solvita
- Elutia Inc.
- Spinal Elements
- Exactech
- Stella Pharmaceuticals
- Ferring Pharmaceuticals
- Stryker
- Fidia
- Takara Bio
- Finceramica
- Tedec-Meiji
- Geistlich
- Terumo
- Globus Medical/NuVasive
- Teva Pharmaceutical
- Hanmi Pharmaceutical
- ThermoGenesis
- Healiva
- TRB Chemedica
- IBSA Pharma
- Viatris
- Integra LifeSciences
- Vericel
- Isto Biologics
- Vivex
- Kolon Tissuegene
- Xtant Medical
- Kuros
- Zimmer Biomet
