Serine Proteases Global Market Report 2024

The serine proteases market size has grown rapidly in recent years. It will grow from $2.04 billion in 2023 to $2.26 billion in 2024 at a compound annual growth rate (CAGR) of 10.9%. The rise during the historical period can be credited to a surge in disease prevalence requiring enzyme treatments, augmented funding and grants allocated to protease-focused research, supportive regulations and incentives, strides in genetic engineering, and heightened demand for serine protease in the food industry.

The serine proteases market size is expected to see rapid growth in the next few years. It will grow to $3.45 billion in 2028 at a compound annual growth rate (CAGR) of 11.2%. The escalation in the projected period is linked to the broadening of industrial applications, heightened awareness and acceptance, increased prevalence of chronic ailments, growing requisition in biotechnology and pharmaceuticals, and a rise in digestive disorders. Key trends in this period encompass technological progress, the development of inhibitors for disease treatment, tailored therapeutic approaches, the integration of CRISPR technology, and advancements in omics technologies.

The expansion of the food and beverage industry is expected to drive the growth of the serine proteases market in the foreseeable future. The food and beverage industry encompasses all aspects of producing, processing, packaging, distributing, and selling food and drink products. This expansion is fueled by factors such as the increasing global population, urbanization trends, and advancements in production, processing, and distribution methods aimed at enhancing efficiency. Serine proteases find widespread application in the food and beverage industry, where they play a crucial role in enhancing product quality, flavor, and functionality, thereby fostering innovation and efficiency. For example, as reported by the Australian Bureau of Statistics in April 2024, sales of food and non-alcoholic beverages in Australia's retail sector showed a steady increase, totaling 15.1 million tonnes in the fiscal year 2021-22 compared to 14.8 million tonnes in the previous fiscal year. Thus, the expansion of the food and beverage industry is a key driver behind the growth of the serine proteases market.

Leading companies in the serine protease market are dedicated to developing innovative solutions to meet the growing demand across various sectors, including pharmaceuticals, biotechnology, and industrial processes. High-performance protease enzymes represent one such innovation, engineered for superior catalytic efficiency, stability, and selectivity. These enzymes demonstrate increased turnover rates and enhanced resistance to extreme conditions. For instance, Biocatalysts Ltd., a UK-based biotechnology company, introduced Promod 324L in November 2021, a novel protease enzyme specifically designed for the pet food sector. This enzyme offers several advantages, including improved processability of animal protein by increasing solubility and reducing viscosity, efficient breakdown of tough animal tissue to yield protein hydrolysates with enhanced protein content, and enhanced digestibility of animal protein, thereby improving nutritional absorption and maximizing the value of previously discarded by-products.

In March 2024, Novus International Inc., a US-based company specializing in animal health and nutrition, acquired BioResource International Inc. The acquisition enables Novus to integrate BRI's existing product range and gain control of its facilities in North Carolina, USA. BioResource International Inc. is a prominent provider of serine proteases, further strengthening Novus's position in the market.

Major companies operating in the serine proteases market are BASF SE, Thermo Fisher Scientific Inc., Roche Holdings Inc., Merck KGaA, Lonza Group, Novozymes A/S, QIAGEN N.V., GenScript Biotech Corporation, Promega Corporation, BioLegend Inc., R&D Systems Inc., Sino Biological Inc., Codexis Inc., New England Biolabs Inc., BBI Solutions Ltd., BRAIN Biotech AG, Cayman Chemical Company, RayBiotech Inc., BioCat GmbH, Enzo Life Sciences Inc., ProSpec-Tany TechnoGene Ltd.

Asia-Pacific was the largest region in the serine proteases market in 2023. The regions covered in the serine proteases market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

The countries covered in the serine proteases market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Serine proteases, characterized by a distinct structure comprising two beta-barrel domains converging at the catalytic active site, are enzymes responsible for cleaving peptide bonds in proteins. These enzymes are found widely across both eukaryotes and prokaryotes and participate in various physiological and pathological processes.

The primary types of serine protease include c1r, c1s, c3a, and c3b. C1r, for instance, plays a crucial role in activating the complement system, an integral part of the immune system tasked with bolstering the body's defenses against infections and eliminating pathogens. These enzymes find application in diverse fields such as the digestive system, blood coagulation system, complement system, among others, catering to end users in sectors such as dietary supplements, nutraceuticals, pharmaceuticals, and industrial applications.

The serine protease research report is one of a series of new reports that provides serine protease market statistics, including the serine protease industry's global market size, regional shares, competitors with a serine protease market share, detailed serine protease market segments, market trends and opportunities, and any further data you may need to thrive in the serine protease industry. This serine protease market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The serine proteases market consists of sales of trypsin, chymotrypsin, thrombin, and elastase. Values in this market are ‘factory gate’ values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.


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