Serine Proteases Market Report 2025

This Serine Proteases market report provides a comprehensive analysis of the market’s characteristics, size, and growth, including segmentation, regional and country-level breakdowns, competitive landscape, market shares, trends, and strategies. It also tracks historical and forecasted market growth across various geographies.

The serine proteases market size has grown rapidly in recent years. It will grow from $2.26 billion in 2024 to $2.52 billion in 2025 at a compound annual growth rate (CAGR) of 11.4%. The growth in the historic period can be attributed to increasing prevalence of diseases where enzyme, increased funding and grants for protease-related research, regulatory support and incentives, advancements in genetic engineering, and rise in demand for serine protease in food.

The serine proteases market size is expected to see rapid growth in the next few years. It will grow to $3.83 billion in 2029 at a compound annual growth rate (CAGR) of 11%. The growth in the forecast period can be attributed to expansion of industrial applications, growing awareness and adoption, rising prevalence of chronic diseases, increasing demand in biotechnology and pharmaceuticals, and increasing incidence of digestive disorders. Major trends in the forecast period include technological advancements, development of inhibitors for treating diseases, customized therapeutic approaches, adoption of CRISPR technology, and advancements in omics technologies.

The growth of the serine proteases market is expected to be driven by the expansion of the food and beverage industry. This sector includes all businesses involved in producing, processing, packaging, distributing, and selling food and drink items. The food and beverage industry's growth is primarily fueled by factors such as the rising global population, increased urbanization, and advancements in production, processing, and distribution technologies that enhance efficiency. Serine proteases play a significant role in improving the quality, flavor, and functionality of food and beverages, thereby fostering innovation and efficiency within the industry. For example, in October 2023, the Agriculture and Agri-Food Department of Canada reported that processed food and beverage exports reached a record $54.3 billion in 2022, a 14.1% increase from the previous year, accounting for 34.7% of the total production value. As a result, the growth of the food and beverage industry is directly contributing to the expansion of the serine proteases market.

Leading companies in the serine protease market are concentrating on developing innovative solutions, such as protease enzymes, to boost drug effectiveness, optimize industrial processes, and create advanced formulations for personal care products. This emphasis on innovation drives market growth while addressing the unique needs of various industries. Protease enzymes act as biological catalysts that break down proteins into smaller peptides or amino acids by cutting peptide bonds. For example, in May 2024, Biocatalysts Ltd., a biotechnology firm based in the UK, introduced PromodTM 327L and PromodTM 295L. These advanced protease enzymes improve the efficient hydrolysis of collagen into neutral-tasting, low molecular-weight peptides, offering benefits such as enhanced flavor, reduced processing times, and greater flexibility for use in dietary supplements, cosmetics, and biomedical applications.

In March 2024, Novus International Inc., a US-based company specializing in animal health and nutrition, acquired BioResource International Inc. The acquisition enables Novus to integrate BRI's existing product range and gain control of its facilities in North Carolina, USA. BioResource International Inc. is a prominent provider of serine proteases, further strengthening Novus's position in the market.

Major companies operating in the serine proteases market are BASF SE, Thermo Fisher Scientific Inc., Roche Holdings Inc., Merck KGaA, Lonza Group, Novozymes A/S, QIAGEN N.V., GenScript Biotech Corporation, Promega Corporation, BioLegend Inc., R&D Systems Inc., Sino Biological Inc., Codexis Inc., New England Biolabs Inc., BBI Solutions Ltd., BRAIN Biotech AG, Cayman Chemical Company, RayBiotech Inc., BioCat GmbH, Enzo Life Sciences Inc., ProSpec-Tany TechnoGene Ltd.

Asia-Pacific was the largest region in the serine proteases market in 2024. The regions covered in the serine proteases market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the serine proteases market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Serine proteases, characterized by a distinct structure comprising two beta-barrel domains converging at the catalytic active site, are enzymes responsible for cleaving peptide bonds in proteins. These enzymes are found widely across both eukaryotes and prokaryotes and participate in various physiological and pathological processes.

The primary types of serine protease include c1r, c1s, c3a, and c3b. C1r, for instance, plays a crucial role in activating the complement system, an integral part of the immune system tasked with bolstering the body's defenses against infections and eliminating pathogens. These enzymes find application in diverse fields such as the digestive system, blood coagulation system, complement system, among others, catering to end users in sectors such as dietary supplements, nutraceuticals, pharmaceuticals, and industrial applications.

The serine protease research report is one of a series of new reports that provides serine protease market statistics, including the serine protease industry's global market size, regional shares, competitors with a serine protease market share, detailed serine protease market segments, market trends and opportunities, and any further data you may need to thrive in the serine protease industry. This serine protease market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The serine proteases market consists of sales of trypsin, chymotrypsin, thrombin, and elastase. Values in this market are ‘factory gate’ values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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