Market Overview:
The molecular weight segment in the United States is a segment of the life sciences & biotechnology industry. Molecular weight markers, also known as the protein ladders or DNA ladders, are essential tools used in various laboratory techniques, including gel electrophoresis. These markets consist of a mixture known-sized DNA or protein fragments, which serve as reference points for determining the size of unknown molecules on gel.The demand for molecular weight markers is strongly related to the advancements in biotechnology & life sciences research. As techniques like gel electrophoresis, Western blotting & polymerase chain reaction (PCR) continue to be fundamental to these fields, the need for accurate molecular weight determination remains strong. The pharmaceutical industry relies on molecular weight markers for protein analyses & other research related to drug discovery & development. Proteins & DNA fragments play a crucial role in understanding diseases & developing targeted therapies. Thermo Fisher Scientific, Bio-Rad Laboratories, Promega Corporation are some of the leading players in the market, who are known for providing protein weight markers.
The USA Molecular Weight Market has been relatively consolidated, with a few key players dominating the industry. Companies like Thermo Fisher Scientific, Bio-Rad Laboratories & New England Biolabs are some of the players in the market. These companies offer a wide range of applications in molecular biology research like DNA & protein gel electrophoresis.
USA Molecular Weight Marker Market Analysis
The American market for molecular weight markers is heavily influenced by the presence of numerous large pharmaceutical & biotechnology companies & the growing burden of various infectious & chronic diseases.The Center for Disease Control & Prevention (CDC) allocated $90 million to the Pathogen Genomic Center of Excellence (PGCoE) network, which is intended to foster & raise innovation & technical capacity in pathogen genomics, molecular epidemiology to prevent, control & respond to microbial threats of public importance.
Taking a patient-centric approach to treat hypertension, a study published in the Journal of the American College of Cardiology demonstrated how a drug plus software-as-a-medical-device (SaMD) combination product can facilitate personalized drug optimization by integrating real-time patient feedback & closed loop model of care with traditional therapeutics.
The molecular weight marker market is majorly driven by the growing number of biotech companies in the United States. Roche has made a research agreement with the Stratos Genomics, a biotechnology firm in the US to support the company’s use of single-molecule sequencing of DNA fragments utilizing protein nanopores.
Key Trends by Market Segment:
- By Type: Prestained markers have been the dominant segment in 2022. The primary reason is that the prestained markers are ready to use product, thus eliminating the time researchers need to stain gels post-electrophoresis. This convenience is a major reason for the growing demand, particularly appealing in busy research & clinical settings where time is of essence
- By Application: Nucleic acid applications have been the dominant segment in 2022. These are frequently used for molecular diagnostic assays, including tests for genetic disorders, infectious diseases & cancer mutations. Molecular weight markers are essential for validating the size of amplified or extracted nucleic acid
- By Geography: In 2022, the Eastern region of the United States has been the dominant region. This includes regions like Massachusetts,New York, New Jersey, Pennsylvania & Maryland which are home to renowned research institutions, universities, biotechnology companies & pharmaceutical firms
The Eastern region is at the forefront of emerging research areas like genomics, gene editing, synthetic biology & personalized medicine. These fields rely heavily on molecular weight marking for tasks like sizing DNA fragments, verifying gene edits & analysing protein expression.
Competitive Landscape:
The USA Molecular Weight Marker Market has been characterized by a dynamic & rapidly evolving environment. Molecular weight markers, also known as protein ladders or DNA ladders, are used in various laboratory applications, particularly in gel electrophoresis which estimates the size of DNA, RNA & other protein-based elements. Numerous companies & research institutions have been engaged in the development & commercialization of molecular weight markers. These include prominent players like Thermo Fisher Scientific, Illumina, Qiagen, Bio-Rad Laboratories which offer a range of products & services related to genotyping, sequencing & molecular weight marker analysis. Many players in the market formed collaborations & partnerships with academic institutions, research organizations & other stakeholders to leverage their expertise & resources. This facilitated the development of comprehensive solutions & accelerated the pace of innovation.Recent Developments:
Creative Enzymes announced the release of their new line of highly efficient & cost-effective DNA markers & ladders which quickly gained popularity in the research market.Bio-Rad Laboratories, a well-known manufacturer of molecular weight markers, announced its acquisition of all the outstanding shares of Curiosity Diagnostics from Scope Fluidics. The acquisition aimed to strengthen Bio-Rad’s position in the molecular diagnostics market & expand its product offerings.
In 2022, New England Biolabs released a new kit for DNA fingerprinting using molecular weight markers.
Future Outlook:
USA Molecular Weight Marker Market is expected to show increasing and is expected to grow at a CAGR of ~11% from 2022 to 2028 with increasing innovations in the life sciences & personalized medicine.Advances in biotechnology & genomics research will lead to the development of new & improved molecular weight markers with higher accuracy, wider range & better resolutions.
The level of research genomics, proteomics & molecular biology play a significant role. As long as the fields continue to grow, the demand for molecular weight markers to aid in experiments will likely to be stronger.
Automation in research processes is becoming increasingly important. If automation becomes more prevalent in laboratories, it could lead to a higher demand for pre-packaged quality controlled molecular weight markers.
Molecular weight markers are not only used in research but also in clinical & diagnostic solutions. The increasing adoption of molecular techniques in medical diagnostics could impact the demand for molecular weight markers.
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Table of Contents
Companies Mentioned (Partial List)
A selection of companies mentioned in this report includes, but is not limited to:
- Thermo Fisher Scientific
- Bio-Rad Laboratories
- New England Biolabs (NEB)
- Promega Corporation
- Agilent Technologies
- VWR International
- Lucigen Corporation