Tinnitus: Pathophysiology and Treatment. Progress in Brain Research Volume 166

Table of Contents

Foreword
General introduction
Tinnitus: Presence and future
Consensus statements:

SECTION I PATHOPHYSIOLOGY
1. Genetics of chronic tinnitus
2. The role of neural plasticity in tinnitus
3. Pathophysiology of tinnitus
4. Applications of magnetic resonance spectroscopy to tinnitus research:
5. Abnormal FMRI activation in the auditory midbrain of people with tinnitus
6. Functional imaging of chronic tinnitus: the use of positron emission tomography
7. The sound of silence decrypting the neural code of tinnitus
8. Tinnitus and Pain ? similarities and differences

SECTION II ANIMAL MODELS
1. The role of the dorsal cochlear nucleus
2. Neural mechanisms underlying somatic tinnitus
3. Behavioral tests for the detection of tinnitus in animals
4. Role of cochlear NMDA receptors in salicylate induced tinnitus

SECTION III EPIDEMIOLOGY
1. Tinnitus, hyperacusis, sound annoyance and loudness hypersensitivity in children
2. Classification and epidemiology of tinnitus

SECTION IV DIAGNOSIS AND EVALUATION OF TINNITUS
1.Clinical diagnosis of tinnitus
2. Evoked potentials in diagnosis of tinnitus.
3. Myofascial trigger points: another way of modulating tinnitus
4. Can somatic testing identify subjects whose tinnitus can be suppressed by specific treatments?
5. Assessment of temporomandibular joint disorders and cervical muscular dysbalance in tinnitus patients
6. Tinnitus severity, depression and personality
7. Insomnia in Tinnitus patients

SECTION V TREATMENT
Tinnitus treatment State of the Art
A. Drug treatment of tinnitus
1. Pharmacological treatment of tinnitus
2. Intratympanic drugs for the treatment of tinnitus
3. Accamprosate
4. Zinc
5. Aprazolam
6. Gabapentin
7. Misoprostol
8. Botox
9. Antioxidants, metals, vitamins and herbal remedies in tinnitus therapy
B. Hearing Devices
1. Hearing aids for the treatment of Tinnitus
2. Implantable Hearing aids for the treatment of Tinnitus
3. Cochlea Implants
C. Electrical and magnetic stimulation
1. TMS for treatment of chronic tinnitus clinical effects
2. TMS for treatment of chronic tinnitus neurobiological effects
3. Electrical brain stimulation for tinnitus
4. TENS for treatment of Tinnitus
D. Cognitive Behavioral Therapy
1. Tinitus Retraining Therapy
2. Auditory and visual attention process training for tinnitus treatment
3. An extinction training for tinnitus
4. Auditory discrimination therapy (adt) for tinnitus management: clinical trial
5. Neurofeedback for treating tinnitus

Section VI ASSESSMENTS OF TREATMENT RESULTS
1. Considerations for the design of clinical trials for tinnitus
2. Randomized, double blind studies
3. Tinnitus assessment instruments

Authors

Aage R. Moller The University of Texas at Dallas, Callier Center for Communication Disorders, Dallas, TX, USA. Dr. Møller is currently the M.F. Jonsson Professor of Hearing, University of Texas at Dallas, the Callier Center for Communication Disorders. He was on the faculty of the University of Pittsburgh School of Medicine for 19 years, where he held positions as Research Professor of Otolaryngology and later of Neurological Surgery. From 1988 to 1997 he held the position of Professor of Neurological Surgery. He received his medical education at the Karolinska Institutet in Stockholm, Sweden, where he also held faculty positions for more than 10 years. Dr. Møller is founder and Editor-in-Chief of the international journal Hearing Research. Berthold Langguth University of Regensburg, Germany. Berthold Langguth is at University of Regensburg, Germany. Goran Hajak Tobias Kleinjung University Hospital Zurich, Switzerland. Tobias Kleinjung is at University Hospital Zurich, Switzerland. Anthony Cacace