This volume provides a novel insight to the evolutionary and comparative aspects of nitric oxide- nitric oxide synthase system as a central regulator of invertebrate and vertebrate homeostasis. By critically selecting and summarizing the ever-increasing number of original studies, these presentations review a variety of important signalling and modulatory roles played by nitric oxide at molecular, cell, organ and organ system levels. It addresses not only specialists and graduate students in the field, but also all biologists concerned with how this unique, gaseous, pleiotropic molecule has been employed by living systems, uncovering a new dimension of the wonders of life.
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Table of Contents
1. On the Comparative Biology of NO Synthetic Pathways: Parallel Evolution of NO-Mediated Signaling2. Nitric Oxide Biogenesis, Signalling and Roles in Molluscs: The Sepia officinalis Paradigm
3. Soluble Guanylyl Cyclases in Invertebrates: Targets for NO and O2
4. Nitric Oxide Signalling in Insect Epithelial Transport
5. Nitric Oxide/Cyclic GMP Signaling and Insect Behavior
6. Impact of Nitrative/Nitrosative Stress in Mitochondria: Unraveling Targets for Malaria Chemotherapy
7. Effects of S-Nitrosation of Nitric Oxide Synthase
8. Regulatory Role and Evolution of Unconventional NOS-Related RNAs
9. The Role of Blood Nitrite in the Control of Hypoxic Vasodilation
10. Nitrite is a Vascular Store of NO which Mediates Hypoxic Signaling and Protects against Ischemia/Reperfusion Injury
11. Nitric Oxide and the Zebrafish (Danio rerio): Developmental Neurobiology and Brain Neurogenesis
12. NO in the Development of Fish
13. Role of Nitric Oxide in Vascular Regulation in Fish
14. NOS Distribution and NO Control of Cardiac Performance in Fish and Amphibian Hearts
15. Nitric Oxide and Histamine in Hibernation and Neuroprotection
16. Nitric Oxide, Peroxynitrite and Matrix Metalloproteinases: Insight into the Pathogenesis of Sepsis
Author
Tota, Bruno.Trimmer, Barry.
