This practical, easy-to-use guide, named to Doody's Core Titles 2013, addresses interference issues in all laboratory tests, including patient epigenetics, process of specimen collection, enzymes, biomarkers. Clinicians and laboratory scientists can therefore rely on one reference which speaks to both their needs of accurate specimen analysis and optimal patient care.
Erroneous hospital and pathology laboratory results can be confusing and problematic, especially in acute care situations. While some factors creating interference, can be identified in the laboratory, detecting many others is often dependent on clinical details unavailable to the laboratory scientists or pathologists. Therefore, clinicians must become proficient in identifying such erroneous reports, and working with pathologists and laboratory scientists so that they can understand the source of such interferences, correct the results, and then decide what course of action must be followed for proper patient management.
- Named to Doody's Core Titles 2013, a collection development tool for health sciences libraries of all sizes, by Doody Enterprises
- Practical information for both clinicians and laboratory scientists, presented in the form of tables and charts for easy reference
- Focus on range and sources of interferences rather than details of toxicologic mechanisms which are well covered in toxicology textbooks
- Covers interferences across endocrine, oncology, hematology, immunohistochemistry, immunology, serology, microbiology, and molecular testing
Table of Contents
Chapter 1. Variation, Errors, and Quality in the Clinical Laboratory
Chapter 2.
Effect of Age, Gender, Diet, Exercise and Ethnicity on Laboratory Test Results
Chapter 3. Effect of patient preparation, specimen collection, anticoagulants and preservatives on laboratory tests
Chapter 4. Sample processing and specimen misidentification issues
Chapter 5. Hemolysis, lipemia and high bilirubin: effect on laboratory tests
Chapter 6. Immunoassay design and mechanism of interferences
Chapter 7. Effect of herbal remedies on clinical laboratory tests
Chapter 8. Challenges in routine clinical chemistry: analysis of small molecules
Chapter 9. Challenges in routine clinical chemistry: proteins and enzymes
Chapter 10. Sources of inaccuracy in biochemical genetics analysis
Chapter 11. Challenges in endocrinology testing
Chapter 12. Pitfalls in tumor marker testing
Chapter 13. Issues of interferences in therapeutic drug monitoring
Chapter 14. Limitations of drugs of abuse testing
Chapter 15. Challenges in confirmation testing for drugs of abuse
Chapter 16. Alcohol determination using automated analyzers: limitations and pitfalls
Chapter 17. Pre-analytical issues and interferences in transfusion medicine tests
Chapter 18. Critical issues in immunology and serology testing
Chapter 19. Sources of errors in hematology and coagulation testing
Chapter 20. Challenges in Clinical Microbiology Testing
Chapter 21. Sources of errors in molecular testing
Chapter 22. Problems in Pharmacogenomics Testing
