The Laboratory Mouse. Edition No. 2

Table of Contents

Part 1 History and Genetics
1.1 Origin and Phylogenetic Relationship of the Laboratory Mouse
1.2 Historical Foundations
1.3 Strains, Stocks and Mutant Mice
1.4 Mouse Genomics
1.5 Generation of Mouse Mutants by Genotype-driven Mutagenesis

Part 2 Anatomy and Normative Biology
2.1 Early Mouse Development
2.2 Gross Anatomy
2.3 Histology
2.4 Skin and Adnexa of the Laboratory Mouse
2.5 Development and Disease of Mouse Muscular and Skeletal Systems
2.6 The Cardiovasular System
2.7 The Respiratory Tract
2.8 The Gastrointestinal System and Metabolism
2.9 Hematology
2.10 Studying Immunology in Mice
2.11Behaviour
2.12 Biological Rhythm of the Mouse

Part 3 Neoplasms and Infectious Diseases
3.1 Diversity of Spontaneous Neoplasms in commonly used Inbred Strains of Laboratory Mice
3.2 Viral Infections
3.3 Bacterial Infections of the Laboratory Mouse
3.4 Parasitic Infections of the Laboratory Mouse

Part 4 Husbandry and Maintenance
4.1 Housing and Maintenance
4.2 Mouse Enrichment
4.3 Nutrition of the Laboratory Mouse
4.4 Health Management and Monitoring
4.5 Genetic Monitoring
4.6 Gnotobiology and Breeding Techniques
4.7 Cryopreservation of Pre-implantation Embryos and Gametes and associated Methods

Part 5 Procedures
5.1 Handling and Restraint
5.2 Routes of Administration
5.3 Collection of Body Fluids
5.4 Anaesthesia, Analgesia and Euthanasia
5.5 Imaging the Laboratory Mouse in vivo
5.6 Necropsy Methods

Part 6 Legal Regulations
6.1 Laws, Guidelines and Policies governing the Use of Mice in Research