The current state of knowledge on this increasingly important subject is beautifully described in this, the first truly comprehensive text of allergic diseases affecting the major veterinary species. It will be an invaluable guide to students, clinicians and researchers alike. From the Foreword by Professor Richard Halliwell, MS, PhD, VetMB, MRCVS, Dip ACVD
Veterinary Allergy is the first comprehensive, high quality reference dealing with all aspects of veterinary allergy in all species and all body systems involved with allergy. Providing solid breadth and excellent depth of coverage, it deals with the immunopathology of the various allergic conditions as well as with clinical presentation, diagnosis and treatment of veterinary allergic diseases.
Key features:
- Broad species coverage, organised by sections on dogs, cats, horses, and other domestic species including large animals, birds and small mammals
- Provides details on diseases affecting the skin, respiratory tract and gut
- Contains practical information for clinicians on management of allergic diseases
- Includes fully-referenced high level detail suitable for specialists and researchers
- Focused on evidence-based medicine and science
- The editors have extensive experience and are respected as world-wide experts in the field
- Every chapter is written by an expert in that particular topic
Anyone seeking information and references on any aspect of allergic conditions in any species should find this book helpful. The book will be of interest to clinicians in first opinion practice, specialists in veterinary dermatology, gastroenterology, internal medicine, and immunology as well as specialists-in-training in those fields and veterinary students.
The focus on underlying principles and practical clinical aspects is admirable. Immediately useful for practical utilization by practicing clinicians. Dr. Andrew Mackin BSc BVMS MVS DVSc FACVSc DSAM, Diplomate, American College of Veterinary Internal Medicine, Professor and Service Chief, Small Animal Internal Medicine, Dr. Hugh G. Ward Endowed Chair of Small Animal Veterinary Medicine, College of Veterinary Medicine, Mississippi State University, USA
Table of Contents
Acknowledgments viii
Contributors ix
Foreword xiii
Richard E.W. Halliwell
Introduction: the immunological basis of allergic diseases xv
Michael J. Day
Part 1 – Canine Allergy (Editor: Chiara Noli) 1
Section 1 – Canine Atopic Dermatitis 3
1 Introduction: canine atopic dermatitis as an evolving, multifactorial disease 5
Douglas J. DeBoer
2 Canine immunoglobulin E 8
Bruce Hammerberg
3 The aberrant immune system in atopic dermatitis 16
Rosanna Marsella
4 Allergens and environmental influence 24
Pascal Prélaud
5 The genetics of canine atopic dermatitis 32
Tim Nuttall
6 Skin barrier and its role in the pathophysiology of atopic dermatitis 42
Koji Nishifuji
7 The role of bacterial agents in the pathogenesis of canine atopic dermatitis 51
David H. Lloyd
8 The role of fungal agents in atopic dermatitis 58
Ross Bond
9 Clinical signs of canine atopic dermatitis 65
Claude Favrot
10 Diagnosis of canine atopic dermatitis 70
Craig E. Griffin
11 Allergen avoidance 78
Daniel O. Morris
12 Allergen-specific immunotherapy 85
Ralf S. Mueller
13 Guidelines for symptomatic medical treatment of canine atopic dermatitis 90
Douglas J. DeBoer
14 Non-conventional treatments 96
Ralf S. Mueller
Section 2 – Food Hypersensitivity 101
15 The pathogenesis of food allergy 103
Hilary A. Jackson
16 Cutaneous manifestations of food hypersensitivity 108
Didier N. Carlotti
17 Adverse reactions to food: a gastroenterologist’s perspective 115
Paola Gianella
18 Diagnostic workup of food hypersensitivity 119
Edmund J. Rosser Jr
19 Long-term management of food hypersensitivity in the dog 124
Nick J. Cave
Section 3 – Flea Bite Allergy 133
20 Flea biology and ecology 135
Marie-Christine Cadiergues
21 The pathogenesis of flea bite allergy in dogs 140
Richard E.W. Halliwell
22 Clinical signs of flea allergy dermatitis in dogs 145
Emmanuel Bensignor
23 Diagnostic investigation of canine flea bite allergy 149
Dawn Logas
24 Implementing an effective flea control programme 152
Michael W. Dryden
25 Symptomatic relief for canine flea bite hypersensitivity 158
Dawn Logas
Section 4 – Complicating Infections in Allergic Dogs 161
26 Complicating microbial skin infections in allergic dogs 163
Anette Loeffler
27 Otitis in the allergic dog 175
James O. Noxon
Section 5 – Other Allergic Diseases in Dogs 183
28 Contact allergy 185
Rosanna Marsella
29 Venomous insect hypersensitivity 191
Mona J. Boord
30 Canine urticaria and angioedema 195
Peter Hill
Part 2 – Feline Allergy (Editor: Aiden Foster) 201
Section 1 – Cutaneous Allergy in Cats 203
31 Pathogenesis - immunopathogenesis 205
Petra J. Roosje
32 Clinical presentations and specificity of feline manifestations of cutaneous allergies 211
Claude Favrot
33 Complications of cutaneous skin allergies (skin infections) 217
Laura Ordeix
34 Diagnostic investigation of the allergic feline 223
William E. Oldenhoff and Karen A. Moriello
35 Symptomatic treatments 228
Alison B. Diesel
36 Allergen-specific immunotherapy 234
Alison B. Diesel
Section 2 – Feline Asthma 237
37 Feline asthma 239
Carol R. Reinero
Section 3 – Flea Bite Allergy 247
38 Pathogenesis 249
Ross Bond
39 Clinical presentations 252
Dawn Logas
40 Diagnostic workup 255
Dawn Logas
41 Therapy 259
Marie-Christine Cadiergues
Section 4 – Mosquito Bite Allergy 265
42 Mosquito bite 267
Masahiko Nagata
Part 3 – Equine Allergy (Editor: Wayne Rosenkrantz) 271
Section 1 – Culicoides Hypersensitivity and Other Insect Allergies 273
43 Pathogenesis and epidemiology of Culicoides hypersensitivity 275
Bettina Wagner
44 Equine immunoglobulin E 279
Eliane Marti and Eman Hamza
45 Clinical manifestations of Culicoides hypersensitivity 287
Janet D. Littlewood
46 Culicoides hypersensitivity: diagnosis 291
Kerstin Bergvall
47 Culicoides hypersensitivity: therapy 297
Anthony A. Yu
48 Other biting insect allergies 307
Gwendolen Lorch
Section 2 – Atopic Disease in Horses - Atopic Dermatitis and Food Hypersensitivity 327
49 Equine atopic dermatitis: pathogenesis 329
Valerie A. Fadok
50 Clinical aspects of equine atopic disease 334
Wayne Rosenkrantz and Stephen White
51 Equine urticaria 338
Valerie A. Fadok
52 Equine headshaking syndrome 344
Harold C. Schott II and Annette D. Petersen
53 Diagnostic workup of equine atopic disease 353
Wayne Rosenkrantz and Stephen White
54 Equine atopic disease symptomatic therapy and allergen-specific immunotherapy 360
Wayne Rosenkrantz and Stephen White
Section 3 – Recurrent Airway Obstruction and Inflammatory Airway Disease 371
55 Recurrent airway obstruction and inflammatory airway disease 373
Vinzenz Gerber
Section 4 – Contact and Other Allergic Diseases 385
56 Equine allergic contact dermatitis 387
Chris Reeder and Joya Griffin
Part 4 – Allergy in Other Domestic Species (Editor: Aiden Foster) 395
57 Immunopathogenesis of allergic skin disease in livestock 397
Adri van den Broek
58 Psoroptes ovis 402
Adri van den Broek and Stewart T.G. Burgess
59 Allergic diseases of livestock species 411
Aiden P. Foster
60 Allergies in birds 422
Claudia S. Nett-Mettler
61 Allergic diseases in other pets (rodents, rabbits, and ferrets) 428
Ian Sayers
Index 433