Stem Cell Nanoengineering reviews the applications of nanotechnology in the fields of stem cells, tissue engineering, and regenerative medicine. Topics addressed include various types of stem cells, underlying principles of nanobiotechnology, the making of nano-scaffolds, nano tissue engineering, applications of nanotechnology in stem cell tracking and molecular imaging, nano-devices, as well as stem cell nano-engineering from bench to bedside.
Written by renowned experts in their respective fields, chapters describe and explore a wide variety of topics in stem cell nanoengineering, making the book a valuable resource for both researchers and clinicians in biomedical and bioengineering fields.Table of Contents
About the Editors ix
Contributors xi
Preface xvii
Part 1 An Introduction to Stem Cells 1
1 Adult Stem Cells 3
Andreas Nussler and Sahar Olsadat Sajadian
2 Pluripotent Stem Cells 25
Hossein Azizi, Akbar Hajizadeh Moghaddam, and Thomas Skutella
3 Interactions of Stem Cells and Components of the Extracellular Matrix 35
Anna K. Blakney, Julie J. Antetomaso, Winnie W. Leung, and Deok-Ho Kim
4 Regenerative Medicine and Cell Therapy: Past, Present, and Future 47
Hooman Sadri-Ardekani and Anthony Atala
Part 2 An Introduction to Nanotechnology 67
5 Principles of Nanotechnology 69
Jerzy Leszczynski
6 Stem-Cell Nanoengineering: Explorations in a Rapidly Moving Field 87
Abhalaxmi Singh and Sanjeeb K. Sahoo
Part 3 Nanostructures for Stem-Cell Engineering – Engineering Approach 97
7 Nanopatterned Surfaces for Stem-Cell Engineering 99
Waleed Ahmed El-Said, Tae-Hyung Kim, Ki-Bum Lee, and Jeong-Woo Choi
8 Biomimetic Nanostructures by Electrospinning and Electrospraying 123
Elham Vatankhah, Molamma P. Prabhakaran, and Seeram Ramakrishna
9 Nanoparticles for Stem-Cell Engineering 143
Esmaiel Jabbari
10 Toxicology of Nanobiomaterials 171
Shahin Bonakdar and Omid Mashinchian
Part 4 Control of Stem-Cell Fate by Engineering of Microenvironment 185
11 Stem-Cell Responses to Surface Nanotopographies 187
Peng-Yuan Wang and Wei-Bor Tsai
12 Control of Mesenchymal Stem-Cell Fate by Engineering the Nanoenvironment 205
Habib Nikukar, Stuart Reid, Mathis O. Riehle, Adam S.G. Curtis, and Matthew J. Dalby
13 Delivery of Molecules and Genes/Small Interfering RNA into Stem Cells by Nanoengineering 223
Mohsen Ashjari
Part 5 Nanotissue Engineering – Biological Approach along with Differentiation 243
14 Expansion of Stem Cells by Nanotissue Engineering 245
Amir Mellati and Hu Zhang
15 Nanotissue Engineering of Neural Cells 265
Sasan Jalili-Firoozinezhad, Fahimeh Mirakhori, and Hossein Baharvand
16 Nanotechnology and Cardiovascular Tissue Engineering 285
Savneet Kaur and Upasana Rishiraj
17 Nanotissue Engineering of Musculoskeletal Cells 299
Mohamadreza Baghaban Eslaminejad, Leila Taghiyar, and Fatemeh Safari
18 Nanotissue Engineering of Skin Cells 315
Daisy M. Ramos, Aditi Subramanian, Aja Aravamudhan, Matthew Harmon, Roshan James, Namdev B. Shelke, and Sangamesh G. Kumbar
19 High-Throughput Screening of Stem Cell Self-Renewal and Differentiation on Nanomaterials 327
Perry T. Yin, Tae-Hyung Kim, Jeong-Woo Choi, and Ki-Bum Lee
Part 6 Nanotechnology in Stem-Cell Imaging 345
20 Nanotechnology for Cellular Imaging 347
Miroslaw Janowski, P. Walczak, and J.W.M. Bulte
Part 7 Nanotissue Engineering and Clinical Applications 363
21 Advancing Translational Nanotechnology to Clinical Application 365
Michelle Griffin, Shima Salmasi, Naghmeh Naderi, Peter E. Butler, and Alexander M. Seifalian
22 Stem-Cell Nanoengineering from Bench to Bed 381
Omid Mashinchian, Shahin Bonakdar, Shahriar Sharifi, and Morteza Mahmoudi
Index 397
