This issue reviews the role of metals in neurodegenerative diseases; including Parkinson's and Huntington's disease; restless leg syndrome and NBIA disorders; and Wilson's disease and manganese and calcium accumulation disorders. An update on advances in neuroimaging and pathology of metal related disease is also presented.
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Table of Contents
- Editorial: Metal-Related Neurological Disorders: Several New Genes and Better UnderstandingSusanne A. Schneider and Kailash P. Bhatia
- The Relevance of Metals in the Pathophysiology of Neurodegeneration, Pathological Considerations
Kurt A. Jellinger
- Pantothenate Kinase-Associated Neurodegeneration (PKAN) and PLA2G6-Associated Neurodegeneration (PLAN): Review of Two Major Neurodegeneration with Brain Iron Accumulation (NBIA) Phenotypes
Manju A. Kurian and Susan J. Hayflick
- Mitochondrial Membrane Protein-Associated Neurodegeneration (MPAN)
Monika Hartig, Holger Prokisch, Thomas Meitinger and Thomas Klopstock
- BPAN: The Only X-Linked Dominant NBIA Disorder
Tobias B. Haack, Penny Hogarth, Allison Gregory, Holger Prokisch and Susan J. Hayflick
- Neuroferritinopathy
Michael J. Keogh, Christopher M. Morris and Patrick F. Chinnery
- Aceruloplasminemia-An Update
Satoshi Kono
- Therapeutic Advances in Neurodegeneration with Brain Iron Accumulation
Giovanna Zorzi and Nardo Nardocci
- The Neuropathology of Neurodegeneration with Brain Iron Accumulation
Michael C. Kruer
- Imaging of Iron
Petr Dusek , Monika Dezortova and Jens Wuerfel
- The Role of Iron Imaging in Huntington's Disease
Simon J. A. van den Bogaard, Eve M. Dumas and Raymund A.C. Roos
- Lysosomal Storage Disorders and Iron
Jose Miguel Bras
- Manganese and the Brain
Karin Tuschl, Philippa B. Mills and Peter T. Clayton
- Update on Wilson Disease
Annu Aggarwal and Mohit Bhatt
- An Update on Primary Familial Brain Calcification Roberta R. Lemos, J. B. M. M. Ferreira, Matthew P. Keasey and Joao R. M. Oliveira