This volume in the International Review of Neurobiology is a comprehensive overview of the state-of-the-art research into autism pathophysiology. Its chapters cover a wide range of etiologies, from genetics and development to environmental factors. In addition, it discusses key cell and behavioral phenotypes, including cortical and cerebellar phenotypes, as well as language and motor outputs. Finally, this volume's chapters on gene expression in the brain describe how genes may be connected to phenotypes in autism.
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Table of Contents
- Autism Spectrum Disorder and the CerebellumEsther B. E. Becker and Catherine J. Stoodley
- Contribution of Long Noncoding RNAs (lncRNAs) to Autism Spectrum Disorder Risk
Brent Wilkinson and Daniel B. Campbell
- Identifying Essential Cell Types and Circuits in Autism Spectrum Disorders
Susan E. Maloney, Michael A. Rieger, and Joseph D. Dougherty
- Connecting Signaling Pathways Underlying Communication to ASD Vulnerability
Stephanie Lepp, Ashley Anderson, and Genevieve Konopka
- MET Receptor Tyrosine Kinase as an Autism Genetic Risk Factor
Yun Peng, Matt Huentleman, Christopher Smith, and Shenfeng Qiu
- Transcriptional Dysregulation of Neocortical Circuit Assembly in ASD
Kenneth Y. Kwan
- Motor Skill in Autism Spectrum Disorders: A Subcortical View
Leanne Chukoskie, Jeanne Townsend, and Marissa Westerfield
- Orchestration of Neurodevelopmental Programs by RBFOX1: Implications for Autism Spectrum Disorder
Brent R. Bill, Jennifer K. Lowe, Christina T. DyBuncio and Brent L. Fogel
- Immune Dysregulation in Autism Spectrum Disorder
Elaine Y. Hsiao
- Autism Susceptibility Genes and the Transcriptional Landscape of the Human Brain Shingo Miyauchi and Irina Voineagu