Regulated Cell Death Part A & Part B of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in apoptosis focusing on the important areas of intrinsic pathway, extrinsic pathway, caspases, cellular assays and post-apoptotic effects and model organisms; as well as topics on necroptosis and screening approaches.
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Table of Contents
1. Assays for Necroptosis and Activity of RIP Kinases2. IAP Family of Cell Death and Signaling Regulators
3. Activation of the NLRP3 Inflammasome by Proteins that Signal for Necroptosis
4. Characterization of the Ripoptosome and its Components Implications for Anti-Inflammatory and Cancer Therapy
5. Tools and Techniques to Study Ligand-Receptor Interactions and Receptor Activation by TNF Superfamily Members
6. Necrotic Cell Death in Caenorhabditis elegans
7. Noncanonical Cell Death in the Nematode Caenorhabditis elegans
8. Autophagy and Cell Death in the Fly
9. Structural Studies of Death Receptors
10. Use of E2~Ubiquitin Conjugates for the Characterization of Ubiquitin Transfer by RING E3 Ligases such as the Inhibitor of Apoptosis Proteins
11. Multidimensional Profiling in the Investigation of Small-Molecule-Induced Cell Death
