This volume covers research on the interaction of major helminth parasites with the immune system. The main focus of the e-book is the ability of helminths to subvert host immune responses, on the one hand. On the other hand, the immunological armamentarium of the host against invading parasites is described also in the light of new findings on innate and adaptive immunity. These include the discovery of a new category of lymphocytes, innate lymphoid cells, and the role of T helper cels such as Th1, Th2 and Th3 cells, T regulatory (Treg) and Th17 cells in helminth diseases and inflammation. The balance between these two T cell subsets during the various stages of helminth diseases is also discussed. The book concludes with a review of new therapeutic approaches to combat helminth parasites (biotherapy, vaccines and natural products).
Immunity to Helminths and Novel Therapeutic Approaches provides updated information for medical students, clinicians and researchers in the fields of parasitology, applied immunology and novel drug delivery.
Immunity to Helminths and Novel Therapeutic Approaches provides updated information for medical students, clinicians and researchers in the fields of parasitology, applied immunology and novel drug delivery.
Table of Contents
ForewordPreface
List of Contributors
CHAPTERS
1. Neuroendocrine Control of the Immune Response During Helminth Infections
Karen Nava-Castro, Julieta Ivone Castro, Elizabeth Langley and Jorge Morales-Montor
2. The Immune Response During Toxocariosis by Toxocara Canis
Fernando Alba-Hurtado, Lorena Chávez-Guitrón, Victor Hugo del Río-Araiza, Karen Nava-Castro and Jorge Morales-Montor
3. Mechanisms of Immune Modulation by Fasciola Hepatica: The Impact of Innate Immune Cells on the Developing Adaptive Immune Response
Sandra M. O’Neill and Sheila Donnelly
4. Parasite-Mediated Immune Modulation During the Development of Human Cystic Echinococcosis
Elisabetta Profumo, Alessandra Ludovisi, Brigitta Buttari, Maria Angeles Gomez Morales and Rachele Riganò
5. The Immunobiology of Urogenital Schistosomiasis
Luke F. Pennington and Michael H. Hsieh
6. The Translational Immunology of Trichinellosis: From Rodents to Humans
Fabrizio Bruschi and Maria Angeles Gómez-Morales
7. Anisakis Simplex Infestation and Immune-Mediated Responses
Ventura M. Teresa, Buquicchio Rosanna, F. Gatti, F.L. Traetta and G. Iadarola
8. Immunomodulation by Parasitic Helminths and its Therapeutic Exploitation
Miguel Angel Pineda and William Harnett
9. Parasites-Based Immunotherapy to Treat Allergies and Autoimmune Diseases
Camila Alexandrina Figueiredo, Valdirene Leão Carneiro, Ryan Santos Costa, Leonardo Nascimento Santos, Raimon Rios and Neuza M Alcantara Neves
10. The Impact of Helminths on the Human Microbiota: Therapeutic Correction of Disturbed Gut Microbial Immunity
Thea Magrone, Emilio Jirillo and Giuseppe Miragliotta
Subject Index
Samples
LOADING...
