Part one considers the innate and adaptive immune responses seen in fish and shellfish together with the implications of these responses for disease control. The specific immune response of molluscs and crustaceans is considered in depth, along with the role of stress in resistance to infection. Advances in disease diagnostics, veterinary drugs and vaccines are discussed in part two, with quality assurance, the use and effects of antibiotics and anti-parasitic drugs in aquaculture, and developments in vaccination against fish are explored. Part three focuses on the development of specific pathogen-free populations and novel approaches for disease control. Specific pathogen free shrimp stocks, developments in genomics and the use of bacteria and bacteriophages as biological agents for disease control are explored, before the management and use of natural antimicrobial compounds.
With its distinguished editor and expert team of contributors, Infectious disease in aquaculture: prevention and control provides managers of aquaculture facilities and scientists working on disease in aquaculture with a comprehensive and systematic overview of essential research in the prevention and control of infectious disease.
Table of Contents
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Woodhead Publishing Series in Food Science, Technology and Nutrition
Preface
Part I: Immune responses in fish and shellfish and their implications for disease control
Chapter 1: The innate and adaptive immune system of fish
Abstract:
1.1 Introduction
1.2 Overview of immune cells and organs in fish
1.3 Fish innate immune response
1.4 An overview of the adaptive immune response in fish
1.5 Immune regulation: the cytokine network in fish
1.6 Conclusions
Chapter 2: Crustacean immune responses and their implications for disease control
Abstract:
2.1 Introduction
2.2 Cellular defence
2.3 Hematopoiesis
2.4 Defence against viruses
2.5 Pattern recognition in crustaceans
2.6 The prophenoloxidase (proPO) cascade
2.7 Coagulation
2.8 Antimicrobial proteins
2.9 Future trends and conclusions
Chapter 3: Immune responses in molluscs and their implications for disease control
Abstract:
3.1 Introduction
3.2 The molluscan immune system
3.3 Disease control in bivalves
3.4 Conclusions
3.5 Acknowledgements
Chapter 4: Stress and resistance to infectious diseases in fish
Abstract:
4.1 Introduction: disease is not just the presence of pathogens
4.2 Fish immune and stress responses
4.3 Individual variability and population level effects
4.4 Conclusions
Part II: Advances in disease diagnostics, veterinary drugs and vaccines
Chapter 5: Advances in diagnostic methods for mollusc, crustacean and finfish diseases
Abstract:
5.1 Introduction
5.2 Mollusc disease diagnostic methods
5.3 Crustacean disease diagnostic methods
5.4 Finfish disease diagnostic methods
5.5 Future trends
Chapter 6: Quality assurance in aquatic disease diagnostics
Abstract:
6.1 Introduction
6.2 The importance of valid and reliable aquatic disease diagnosis and the role of quality assurance systems
6.3 Sampling submission and handling for aquatic disease diagnosis
6.4 The importance of assay performance in aquatic disease diagnosis
6.5 Validation of quality assurance systems for aquatic diagnostic facilities
6.6 Interpreting and reporting results under a quality assurance system
6.7 Accreditation and auditing of disease diagnostic laboratories
6.8 Conclusions
Chapter 7: Antibiotics in aquaculture: reducing their use and maintaining their efficacy
Abstract:
7.1 Introduction
7.2 The epidemiology and aetiology of bacterial diseases in aquatic animals
7.3 The use of antibiotics in aquaculture
7.4 Efficacy of antimicrobial therapy in aquaculture
7.5 Laboratory detection of clinical resistance
7.6 The Clinical and Laboratory Science Institute (CLSI) approach to susceptibility testing in aquaculture
7.7 Questions concerning the CLSI approach
7.8 Future trends: the way forward for susceptibility testing
7.9 Conclusions
7.10 Acknowledgements
Chapter 8: Considerations for the use of anti-parasitic drugs in aquaculture
Abstract:
8.1 Introduction
8.2 Factors in successful treatment with anti-parasitic drugs
8.3 Trigger points for treatment with anti-parasitic drugs in aquaculture
8.4 Future trends
Chapter 9: Developments in vaccination against fish bacterial disease
Abstract:
9.1 Introduction
9.2 Methods of administration of vaccines for fish
9.3 Determination of effectiveness of the vaccines
9.4 Vaccine composition
9.5 Mode of action of vaccines
9.6 Conclusions
Chapter 10: Developments in adjuvants for fish vaccines
Abstract:
10.1 Introduction
10.2 Fish immune responses: implications for the development of vaccines and adjuvants
10.3 Oil-adjuvanted fish vaccines
10.4 Vaccines adjuvanted with substances other than oil
10.5 Future trends and conclusions
10.6 Acknowledgements
Part III: Development of specific pathogen-free populations and novel approaches for disease control
Chapter 11: Development of specific pathogen-free (SPF) shrimp stocks and their application to sustainable shrimp farming
Abstract:
11.1 Introduction
11.2 A historical perspective on the concept of domesticated specific pathogen-free (SPF) shrimp
11.3 The development of Litopenaeus vannamei as the dominant species in the Americas
11.4 The adaptation of the specific pathogen-free (SPF) concept to domesticated shrimp stocks
11.5 Maintenance of specific pathogen-free (SPF) status: disease surveillance and control programs
11.6 Conclusions
11.7 Acknowledgements
Chapter 12: The role of risk analysis in the development of biosecurity programmes for the maintenance of specific pathogen-free populations
Abstract:
12.1 Introduction
12.2 Aquaculture disease risk analysis
12.3 Application of risk analysis to surveillance and biosecurity strategies
12.4 Constraints and future trends
12.5 Conclusions
Chapter 13: Developments in genomics relevant to disease control in aquaculture
Abstract:
13.1 Introduction
13.2 The genomics toolbox in comparative immunology
13.3 Genomics in finfish disease control
13.4 Genomics in shellfish and crustacean disease control
13.5 Future trends
Chapter 14: Bacteria and bacteriophages as biological agents for disease control in aquaculture
Abstract:
14.1 Introduction
14.2 Isolation of bacteria for biocontrol
14.3 Antagonistic activity of bacterial agents
14.4 Colonization and persistence within the host
14.5 Considerations for the design of pathogen challenge tests
14.6 Safety of bacterial biocontrol agents and perspectives on future development
14.7 Biocontrol using bacteriophages
14.8 Strengths and challenges to phage biocontrol
14.9 Future trends
Chapter 15: Managing the microbiota in aquaculture systems for disease prevention and control
Abstract:
15.1 Introduction
15.2 Control strategies against diseases
15.3 The microbial maturation concept
15.4 Manipulating type and number of bacteria: probiotics and prebiotics
15.5 Managing bacterial activity by means of quorum sensing (QS)
15.6 Host-microbe interactions affecting host health in aquaculture: the need for knowledge
15.7 Conclusions
15.8 Acknowledgements
Chapter 16: Natural antimicrobial compounds for use in aquaculture
Abstract:
16.1 Introduction: microbial diseases in aquaculture
16.2 Current problems in microbial disease control
16.3 Public health and ethical issues relating to the use of antibiotics for disease control in aquaculture
16.4 Alternative antimicrobial compounds
16.5 Origin of alternative antimicrobials
16.6 Plant antimicrobials
16.7 Possible mode of action of herbal antimicrobials
16.8 Routes of administration of antimicrobial herbal extracts to fish and shrimps
16.9 Conclusions
Chapter 17: The potential for antimicrobial peptides to improve fish health in aquaculture
Abstract:
17.1 Introduction
17.2 Strategies for preventing disease in fish
17.3 Antimicrobial peptides (AMPs)
17.4 The potential role of antimicrobial peptides in preventing and treating fish diseases
17.5 Future trends and conclusions
17.6 Acknowledgements
Chapter 18: Advances in non-chemical methods for parasite prevention and control in fish
Abstract:
18.1 Introduction
18.2 Principles of disease management without chemicals
18.3 Preventative measures
18.4 Disease management
18.5 Interventions for parasite prevention and control in fish
18.6 Conclusions
Index
