- Supplies the practicing and trainee hematologist with a practical and immediately applicable compendium of answers to clinical questions
- Covers the spectrum of the hematopoietic cell transplant specialty, in particular practical issues in transplant patient care, and the set up and functioning of a transplant program
- Contains concise chapters written with a focus on tables, algorithms and figures to aid rapid referral
- Benefits from expert contributions from an international authorship
Table of Contents
Contributors, ix
Preface, xiv
1 Donor and graft selection strategy, 1
Ayman Saad, Marisa B. Marques, and Shin Mineishi
2 HLA typing and implications, 9
Bronwen E. Shaw and Stephen R. Spellman
3 RiskÂ]benefit assessment in allogeneic hematopoietic transplant: Factors, scores, and models, 19
Mahmoud Elsawy and Mohamed L. Sorror
4 Donor and recipient preÂ]transplant evaluation, 36
Shuang Fu and Navneet S. Majhail
5 Autologous and allogeneic progenitor cell mobilization, 45
Racquel D. InnisÂ]Shelton and Luciano J. Costa
6 Hematopoietic stem and progenitor cell collection by apheresis: Techniques and tricks, 53
Anand Padmanabhan
7 Hematopoietic cell processing: From procurement to infusion, 59
Jay S. Raval, Kathryn McKay, and Yara A. Park
8 Graft manipulation: T-cell depletion and beyond, 66
Christina Cho and MiguelÂ]Angel Perales
9 GraftÂ]versusÂ]host disease prophylaxis, 73
Melhem Solh and Asad Bashey
10 Acute lymphoblastic leukemia, 80
Ghada Zakout and Adele K. Fielding
11 Acute myeloid leukemia, 89
Hillard M. Lazarus and Masumi Ueda
12 Myelodysplastic syndromes, 97
Melinda Biernacki and H. Joachim Deeg
13 Chronic myelogenous leukemia, 108
Daniel Egan and Jerald Radich
14 Philadelphia chromosome negative myeloproliferative neoplasms, 116
Nicolaus Kröger
15 Chronic lymphocytic leukemia, 123
Fabienne McClanahan Lucas and John Gribben
16 Hodgkin Lymphoma, 131
Anna Sureda and Eva DomingoÂ]Domenech
17 Indolent lymphomas, 140
Narendranath Epperla, Hamza Hashmi, and Mehdi Hamadani
18 Diffuse large B-cell lymphoma, 151
Syed Abbas Ali, Istvan Redei, and Syed A. Abutalib
19 Mantle cell lymphoma, 164
Narendranath Epperla and Timothy S. Fenske
20 T-cell lymphoma, 179
Adrienne A. Phillips and Koen van Besien
21 Primary CNS lymphoma, 188
Henry C. Fung, Philip Pancari, and Patricia Kropf
22 Autologous hematopoietic transplant in multiple myeloma, 194
Nisha S. Joseph, Ajay K. Nooka, and Sagar Lonial
23 Allogeneic hematopoietic transplant in multiple myeloma, 207
Parameswaran Hari and Binod Dhakal
24 LightÂ]chain amyloidosis, 214
Amara S. Hussain and Anita D’Souza
25 Autoimmune disorders, 221
Adam Bryant and Harold Atkins
26 Testicular cancer, 229
Moshe C. Ornstein, Navneet S. Majhail, and Timothy Gilligan
27 Sickle cell disease, 236
Sonali Chaudhury and Shalini Shenoy
28 Hematopoietic cell transplant in thalassemia, 246
Emanuele Angelucci and Federica Pilo
29 Fanconi anemia, 255
Flore Sicre de Fontbrune, Jean Soulier, and Regis Peffault de Latour
30 Immunodeficiency disorders, 264
Jennifer A. Kanakry and Dennis D. Hickstein
31 Inherited metabolic disorders, 272
Jaap Jan Boelens and Robert F. Wynn
32 Aplastic anemia and paroxysmal nocturnal hemoglobinuria, 281
Andrew C. Dietz and Michael A. Pulsipher
33 HIV infection and transplantation, 290
Nitya Nathwani, Stephen J. Forman, and Amrita Krishnan
34 Engraftment and graft failure: Assessment and practical considerations, 297
Yogesh Jethava, Madan Jagasia, Mohamed Mohty, and Bipin N. Savani
35 Immune reconstitution and tolerance, 304
udovic Belle and William R. Drobyski
36 Donor lymphocyte infusion, 315
David C. Halverson and Daniel Fowler
37 Diagnosis and treatment of acute graftÂ]versusÂ]host disease, 324
Natasha Kekre and Vincent T. Ho
38 Diagnosis and treatment of chronic graftÂ]versusÂ]host disease, 334
Sabarinath Venniyil Radhakrishnan and Daniel R. Couriel
39 Prevention and treatment of infection, 348
Corrado Girmenia, Gian Maria Rossolini, and Claudio Viscoli
40 Early nonÂ]infectious complications after hematopoietic cell transplantation, 359
Piyanuch Kongtim and Stefan O. Ciurea
41 PostÂ]transplant lymphoproliferative disorders, 369
Michael D. Keller, Conrad R. Cruz, and Catherine M. Bollard
42 Survivorship issues after transplantation, 376
Vanessa E. Kennedy, Madan Jagasia, and Bipin N. Savani
Index, 384