This “Metastatic Prostate Cancer- Pipeline Insight, 2024” report provides comprehensive insights about 95+ companies and 100+ pipeline drugs in Metastatic Prostate Cancer pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Common symptoms of metastatic prostate cancer includes, bone pain and broken bones for no reason, trouble urinating or decreased force of urine stream, blood in the urine or semen, tiredness/fatigue, swollen breasts, depression, memory loss, and heart problems, unexplained weight loss, erectile dysfunction, unexplained fevers, etc.
The treatment options for metastatic prostate cancer include chemotherapy, hormone therapy, and immunotherapy. Chemotherapy, such as docetaxel, is a common treatment for metastatic prostate cancer, often used in combination with hormone therapy. Hormone therapy works by slowing or blocking the growth of prostate cancer cells by reducing testosterone levels. Immunotherapy, specifically sipuleucel-T, has been approved by the FDA for advanced metastatic prostate cancer, utilizing the immune system to target cancer cells. Additionally, checkpoint inhibitors have been investigated as a type of immunotherapy for prostate cancer treatment. These treatment options aim to reduce symptoms, improve quality of life, and help patients live longer with metastatic prostate cancer.
Prostate cancer is staged using the TNM system, which considers the size and extent of the primary tumor (T), whether it has spread to nearby lymph nodes (N), and whether it has metastasized to distant sites (M). Early-stage prostate cancer is localized to the prostate gland (Stage I-II), while locally advanced disease (Stage III) indicates the tumor has grown outside the prostate. Metastatic prostate cancer (Stage IV) has spread to distant organs or lymph nodes. Factors like PSA levels, tumor grade, and extent of spread are used to further categorize prostate cancer into risk groups, which help guide treatment decisions. Overall, prostate cancer has a high 5-year survival rate, especially when detected and treated early.
"Metastatic Prostate Cancer- Pipeline Insight, 2024" report outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Metastatic Prostate Cancer pipeline landscape is provided which includes the disease overview and Metastatic Prostate Cancer treatment guidelines. The assessment part of the report embraces, in depth Metastatic Prostate Cancer commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Metastatic Prostate Cancer collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
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Geography Covered
- Global coverage
Metastatic Prostate Cancer: Understanding
Metastatic Prostate Cancer: Overview
Metastatic Prostate Cancer refers to the cancer that has spread from the prostate to other parts of the body. It is sometimes called advanced prostate cancer. It most commonly spreads to lymph nodes in other parts of the body or to the bones. It can also spread to other organs such as the lungs. Metastatic prostate cancers show higher levels of active β1 integrin, which confers both an enhanced capacity to colonize distant organs, through the adhesion to ECM molecules like fibronectin and collagen type I, and a survival advantage, through an increase in the resistance to anoikis - the programmed cell death induced by insufficient adhesion to the growth substrate.Common symptoms of metastatic prostate cancer includes, bone pain and broken bones for no reason, trouble urinating or decreased force of urine stream, blood in the urine or semen, tiredness/fatigue, swollen breasts, depression, memory loss, and heart problems, unexplained weight loss, erectile dysfunction, unexplained fevers, etc.
The treatment options for metastatic prostate cancer include chemotherapy, hormone therapy, and immunotherapy. Chemotherapy, such as docetaxel, is a common treatment for metastatic prostate cancer, often used in combination with hormone therapy. Hormone therapy works by slowing or blocking the growth of prostate cancer cells by reducing testosterone levels. Immunotherapy, specifically sipuleucel-T, has been approved by the FDA for advanced metastatic prostate cancer, utilizing the immune system to target cancer cells. Additionally, checkpoint inhibitors have been investigated as a type of immunotherapy for prostate cancer treatment. These treatment options aim to reduce symptoms, improve quality of life, and help patients live longer with metastatic prostate cancer.
Prostate cancer is staged using the TNM system, which considers the size and extent of the primary tumor (T), whether it has spread to nearby lymph nodes (N), and whether it has metastasized to distant sites (M). Early-stage prostate cancer is localized to the prostate gland (Stage I-II), while locally advanced disease (Stage III) indicates the tumor has grown outside the prostate. Metastatic prostate cancer (Stage IV) has spread to distant organs or lymph nodes. Factors like PSA levels, tumor grade, and extent of spread are used to further categorize prostate cancer into risk groups, which help guide treatment decisions. Overall, prostate cancer has a high 5-year survival rate, especially when detected and treated early.
"Metastatic Prostate Cancer- Pipeline Insight, 2024" report outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Metastatic Prostate Cancer pipeline landscape is provided which includes the disease overview and Metastatic Prostate Cancer treatment guidelines. The assessment part of the report embraces, in depth Metastatic Prostate Cancer commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Metastatic Prostate Cancer collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
The companies and academics are working to assess challenges and seek opportunities that could influence Metastatic Prostate Cancer R&D. The therapies under development are focused on novel approaches to treat/improve Metastatic Prostate Cancer.Metastatic Prostate Cancer Emerging Drugs Chapters
This segment of the Metastatic Prostate Cancer report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II/III, II, I, preclinical and discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.Metastatic Prostate Cancer Emerging Drugs
- Saruparib: AstraZeneca
- Onvansertib: Cardiff Oncology
- ONCT-534: Oncternal Therapeutics
- VIO-01: Valerio Therapeutics
- ORIC-944: ORIC Pharmaceuticals
Metastatic Prostate Cancer: Therapeutic Assessment
This segment of the report provides insights about the different Metastatic Prostate Cancer drugs segregated based on following parameters that define the scope of the report, such as:Major Players in Metastatic Prostate Cancer
There are approx. 95+ key companies which are developing the therapies for Metastatic Prostate Cancer. The companies which have their Metastatic Prostate Cancer drug candidates in the most advanced stage, i.e. Phase III include, AstraZeneca.Phases
This report covers around 100+ products under different phases of clinical development like
- Late stage products (Phase III)
- Mid-stage products (Phase II)
- Early-stage product (Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
Route of Administration
Metastatic Prostate Cancer pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as- Intravenous
- Subcutaneous
- Oral
- Intramuscular
- Molecule Type
Products have been categorized under various Molecule types such as
- Monoclonal antibody
- Small molecule
- Peptide
- Product Type
Metastatic Prostate Cancer: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Metastatic Prostate Cancer therapeutic drugs key players involved in developing key drugs.Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Metastatic Prostate Cancer drugs.Metastatic Prostate Cancer Report Insights
- Metastatic Prostate Cancer Pipeline Analysis
- Therapeutic Assessment
- Unmet Needs
- Impact of Drugs
Metastatic Prostate Cancer Report Assessment
- Pipeline Product Profiles
- Therapeutic Assessment
- Pipeline Assessment
- Inactive drugs assessment
- Unmet Needs
Key Questions
Current Treatment Scenario and Emerging Therapies:
- How many companies are developing Metastatic Prostate Cancer drugs?
- How many Metastatic Prostate Cancer drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Metastatic Prostate Cancer?
- What are the key collaborations (Industry-Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Metastatic Prostate Cancer therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for Metastatic Prostate Cancer and their status?
- What are the key designations that have been granted to the emerging drugs?
Key Players
- AstraZeneca
- Cardiff Oncology
- Oncternal Therapeutics
- Valerio Therapeutics
- ORIC Pharmaceuticals
- Astellas Pharma
- MediLink Therapeutics
- Sagimet Biosciences
- Genentech
- Regeneron Pharmaceuticals
- Pfizer
- Orion Pharma
- Allarity Therapeutics
- Janssen Research & Development
Key Products
- Saruparib
- Onvansertib
- ONCT-534
- VIO-01
- ORIC-944
- ZEN003694
- YL201
- TVB-2640
- RO7656594
- REGN5678
- PF-07248144
- ODM-209
- LiPlaCis
- JNJ-78278343
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Table of Contents
IntroductionExecutive SummaryMetastatic Prostate Cancer- Analytical PerspectiveMetastatic Prostate Cancer Key CompaniesMetastatic Prostate Cancer Key ProductsMetastatic Prostate Cancer- Unmet NeedsMetastatic Prostate Cancer- Market Drivers and BarriersMetastatic Prostate Cancer- Future Perspectives and ConclusionMetastatic Prostate Cancer Analyst ViewsMetastatic Prostate Cancer Key CompaniesAppendix
Metastatic Prostate Cancer: Overview
Pipeline Therapeutics
Therapeutic Assessment
Late Stage Products (Phase III)
Saruparib: AstraZeneca
Mid Stage Products (Phase II)
Onvansertib: Cardiff Oncology
Early Stage Products (Phase I/II)
ONCT-534: Oncternal Therapeutics
Preclinical and Discovery Stage Products
Drug name: Company name
Inactive Products
List of Tables
List of Figures
Companies Mentioned (Partial List)
A selection of companies mentioned in this report includes, but is not limited to:
- AstraZeneca
- Cardiff Oncology
- Oncternal Therapeutics
- Valerio Therapeutics
- ORIC Pharmaceuticals
- Astellas Pharma
- MediLink Therapeutics
- Sagimet Biosciences
- Genentech
- Regeneron Pharmaceuticals
- Pfizer
- Orion Pharma
- Allarity Therapeutics
- Janssen Research & Development