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Wilson Disease. Pathogenesis, Molecular Mechanisms, Diagnosis, Treatment and Monitoring

  • Book

  • May 2019
  • Elsevier Science and Technology
  • ID: 4226457

Wilson Disease: Pathogenesis, Molecular Mechanisms, Diagnosis, Treatment and Monitoring translates both clinical and experimental findings into a comprehensive approach for anyone involved in research and patient care. While the clinical variability of Wilson Disease poses a challenge from a diagnostic approach, the book uses the translational impact of new research findings to relate to new treatment concepts. Comprehensive chapters include common knowledge, guideline consensus statements, and discussions of clinical evidence. This is a must-have reference for researchers and clinicians in translational research.

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Table of Contents

1. History of WD 2. Pathogenesis 3. Epidemiology and genetics 4. Diagnosis 5. Treatment Decisions

Authors

Karl Heinz Weiss Department of Gastroenterology, Associate Professor, University Hospital of Heidelberg, Heidelberg, Germany. Dr. Weiss is an Associate Professor at the University Hospital of Heidelberg, Department of Gastroenterology in Heidelberg, Germany. He is the author numerous articles dedicated to Wilson Disease which feature international collaboration. He has been the recipient of The German National Merit Foundation Award as well as the Young Investigator Award. His main areas of research include Wilson Disease, Hepatobiliary Tumors, and Metabolic Liver Diseases. Michael Schilsky Medical Director, Adult Liver Transplant, Yale-New Haven Transplantation Center, New Haven, CT, USA. Michael Schilsky, MD, became medical director of liver transplantation at Yale-New Haven Hospital in 2007, with appointments in medicine and surgery at the Yale School of Medicine. Dr. Schilsky received his medical degree from the University of Chicago, Pritzker School of Medicine. He completed his residency and fellowship in gastroenterology and research training in liver diseases at Albert Einstein College of Medicine and Montefiore Medical Center. His clinical and research interests include transplant hepatology, inherited metabolic disorders of the liver, Wilson disease and hemochromatosis. Dr. Schilsky previously served as director of the liver medicine clinic at the Recanati/Miller Transplantation Institute at Mount Sinai Medical Center and medical director for liver transplantation at the New York Weill Cornell Medical Center, where he developed a comprehensive program for the care and evaluation of liver transplant patients. Dr. Schilsky coauthored the AASLD practice guidelines for Wilson disease and is author of numerous original manuscripts and reviews.