Integrated Nano-Biomechanics provides an integrated look into the rapidly evolving field of nanobiomechanics. The book demystifies the processes in living organisms at the micro- and nano-scale through mechanics, using theoretical, computational and experimental means. The book develops the concept of integrating different technologies along the hierarchical structure of biological systems and clarifies biomechanical interactions among different levels for the analysis of multi-scale pathophysiological phenomena. With a focus on nano-scale processes and biomedical applications, it is shown how knowledge obtained can be utilized in a range of areas, including diagnosis and treatment of various human diseases and alternative energy production.
This book is based on collaboration of researchers from a unique combination of fields, including biomechanics, computational mechanics, GPU application, electron microscopy, biology of motile micro-organisms, entomological mechanics and clinical medicine. The book will be of great interest to scientists and researchers involved in disciplines, such as micro- and nano-engineering, bionanotechnology, biomedical engineering, micro- and nano-scale fluid-mechanics (such as in MEMS devices), nanomedicine and microbiology, as well as industries such as optical devices, computer simulation, plant based energy sources and clinical diagnosis of the gastric diseases.
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Table of Contents
Section 1: Introduction to nano-biomechanicsT. Yamaguchi
Section 2: Biomechanics of microcirculation
Chapter 2.1 Behavior of capsules in flow
S. Nix
Chapter 2.2 Behavior of red blood cells
T. Omori
Chapter 2.3 Adhesion of cells
Y. Imai
Chapter 2.4 Formation and destruction of the primary thrombus
H. Kamada
Section 3: Biomechanics of digestive systems
Chapter 3.1 Dynamics of swallowing
Y. Imai
Chapter 3.2 Mixing in stomach
Y. Imai
Chapter 3.3 Transport phenomena of gut flora
T. Ishikawa
Section 4: Biomechanics for pathology and treatment
Chapter 4.1 Development of cerebral aneurysms
Y. Shimogonya
Chapter 4.2 Electroporation for cancer treatment
N. Matsuki
Chapter 4.3 Microbubbles for blood transfusion
N. Matsuki
Chapter 4.4 Percutaneous absorption of medicine
K. Kikuchi
Section 5: Ciliary motion
Chapter 5.1 Ciliary structure
H. Ueno
Chapter 5.2 Motor proteins of cilia
H. Ueno
Chapter 5.3 Computational modeling of ciliary motion
T. Omori
Section 6: Swimming microorganisms
Chapter 6.1 Swimming of a solitary cell
Y. Shimogonya
Chapter 6.2 Suspension of swimming cells
T. Ishikawa
Chapter 6.3 Bioconvection generated by microalgae
A. Kage
Section 7: Microfluidic devices based on biomechanics
Chapter 7.1 Measurement techniques of cellular flow
R. Lima
Chapter 7.2 Controlling cell-free layer
M. Saadatmand
Chapter 7.3 Separation of motile bacteria
T. Ishikawa
Section 8: Biomimetics
Chapter 8.1
Design of fish fin
K. Kikuchi
Chapter 8.2
Bloodsucking of mosquito
K. Kikuchi
Chapter 8.3
Virtual chameleon
F.Mizuno