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Parkinson's Disease Market Insight, Epidemiology and Market Forecast - 2034

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    Report

  • 318 Pages
  • October 2024
  • Region: Global
  • DelveInsight
  • ID: 4401843
UP TO OFF until Dec 31st 2024

Covers the Therapeutics Market Revenue, Treatment Practice/Algorithm and Forecasted Market Size of Parkinson's Disease (PD) from 2017 to 2025 Segmented by Seven Major Markets

Key Highlights

  • The geographic disparity in the prevalence of H. pylori infection could be due to sanitation, urban versus rural lifestyle, socioeconomic status, variability of the H. pylori strains, and antibiotic usage.
  • The H. pylori infection market is projected to witness consistent growth throughout the forecast period (2023-2034). The market size of H. pylori infection in the 7MM is expected to increase, driven by the increasing prevalent population.
  • The US FDA has approved many therapies, like NEXIUM, PREVPAC, etc., with authorized generics in the market. Cumberland Pharmaceuticals OMECLAMOX-PAK and AbbVie’s PYLERA are the branded versions of clarithromycin triple therapy and bismuth-quadruple therapy.
  • RedHill Biopharma’s TALICIA a recently approved rifabutin-based therapy is a therapy that is prescribed widely as the second-line therapy. Another drug to look out for will be Phathom Pharmaceuticals’ P-CAB combination, VOQUEZNA. Available as triple and dual pak, the drug was approved in 2022 by the US FDA and recently was reformulated and launched in the US in 2023.
  • The current treatment regime for H. pylori aims to eradicate the bacteria, as this alone is paramount for healing associated peptic ulcers and preventing relapses. However, the growing prevalence of antibiotic resistance has made it a global challenge. Triple therapies, which combine antibiotics with either antisecretories, proton pump inhibitors, or other acid-regulating drugs as the first line of treatment for the eradication of H. pylori, are among the majority of treatments recommended by various worldwide guidelines.
  • In 2022, the US had the largest market size of H. pylori infection among the 7MM, accounting for approximately USD 1.06 billion. This is expected to increase further by 2034.
This report delivers an in-depth understanding of Helicobacter pylori Infection, historical and forecasted epidemiology, as well as the Helicobacter pylori Infection market trends in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.

The Helicobacter pylori Infection market report provides current treatment practices, emerging drugs, market share of individual therapies, and current and forecasted 7MM Helicobacter pylori infection market size from 2020 to 2034. The report also covers Helicobacter pylori infection treatment practices/algorithms and unmet medical needs to curate the best opportunities and assess the market’s potential.

Geography Covered

  • The United States
  • EU4 (Germany, France, Italy, and Spain) and the United Kingdom
  • Japan

Study Period: 2020-2034

Helicobacter pylori Infection Understanding and Treatment Algorithm

Helicobacter pylori Infection Overview

Helicobacter pylori (H. pylori) is a spiral-shaped, flagellated Gram-negative bacterium colonizing the human stomach that usually infects the stomach and small intestine. It is one of the most common chronic bacterial infections worldwide, usually acquired during childhood, yet most infected individuals remain asymptomatic.

Helicobacter pylori Infection Diagnosis

There is no single accurate diagnostic tool or method, and the current diagnosis regime is usually a combination of invasive and noninvasive methods.

The noninvasive methods that determine eradication rates are based on the presence of bacterial enzymes, antigens, antibodies, or DNA sequences and include 13C or 14C UBT, SAT, serology, etc. In contrast, the invasive methods include endoscopy and gastric biopsy followed by RUT, histology, culture, or a clinically significant PCR.

Helicobacter pylori Infection Treatment

The treatment regime for H. pylori infection is therapeutic and not prophylactic. The current treatment aims to eradicate the bacteria, but with increasing antibiotic resistance, the cure rates have declined with a simultaneous increase in re-infection.

The US FDA has approved many therapies over the years, like NEXIUM, PREVPAC, etc., that even have their approved generics in the market.

The US FDA development of including H. pylori infection in the GAIN pathogen list has led to major changes in the approved market scenario, as many novel therapies received approval in the past couple of years with Phathom Pharmaceuticals P-CAB combination VOQUEZNA TRIPLE and DUAL PAK being the most recent. Others include TALICIA, OMECLAMOX-PAK, and PYLERA, among others.

Helicobacter pylori Infection Epidemiology

As the market is derived using a patient-based model, the Helicobacter pylori Infection epidemiology chapter in the report provides historical as well as forecasted epidemiology segmented by total diagnosed prevalent cases of helicobacter pylori infection, gender-specific diagnosed prevalent cases of helicobacter pylori infection, and age-specific diagnosed prevalent cases of helicobacter pylori infection in the 7MM covering the United States, EU4 countries (Germany, France, Italy, and Spain) and the United Kingdom, and Japan from 2020 to 2034.
  • In the 7MM, the total diagnosed prevalent cases of helicobacter pylori infection were estimated to be approximately 321,217,226 in 2022, of which the US accounted for around 37%, while EU4 and the UK accounted for nearly 43%, and Japan accounted for approximately 20% of the total diagnosed prevalent cases.
  • Among the 7MM, the US accounted for nearly 118,650,370 total diagnosed prevalent cases of helicobacter pylori infection, in 2022. These cases are expected to increase during the study period due to an increase in disease awareness and diagnosis.
  • As per analysis, EU4 and the UK accounted for around 138,397,508 diagnosed prevalent cases of helicobacter pylori infection in 2022. These cases are expected to change during the study period (2020-2034).
  • Among the EU4 and the UK, France accounted for the highest diagnosed prevalent cases of helicobacter pylori infection, representing nearly 23% of the cases, followed by Germany and Italy, while the UK had the least cases in 2022.
  • According to estimates based on the analyst's epidemiology model, helicobacter pylori infection exhibits a higher male preponderance than females in the US. Of the total diagnosed prevalent cases in the US, nearly 52% were males and 48% were females, in 2022.
  • In the US, the highest age-specific diagnosed prevalent cases of helicobacter pylori infection were for the age group above 40 years, with nearly 77,122,741 cases, in 2022. As per the analysis, these cases are expected to increase, and the age group 20-40 years will contribute around 25% of the diagnosed prevalent cases, while the age groups 0-20 years will contribute 10% respectively by 2034.
  • In 2022, among the 7MM, Japan had the second-highest cases of Helicobacter pylori infection, with approximately 64,169,348 total diagnosed prevalent cases of Helicobacter pylori infection.

Helicobacter pylori infection Drug Chapters

The drug chapter segment of the helicobacter pylori infection report encloses a detailed analysis of helicobacter pylori infection-marketed drugs and mid to late-stage (Phase III and Phase II) pipeline drugs. It also helps understand the helicobacter pylori infection clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug, and the latest news and press releases.

Marketed Drugs

TALICIA (RHB-105): RedHill Biopharma

TALICIA (RHB-105) is an oral, all-in-one capsule with a three-drug combination of omeprazole, a PPI, amoxicillin, a penicillin-class antibacterial, and rifabutin, a rifamycin antibacterial, indicated for the treatment of H. pylori infection in adults. To reduce the development of drug-resistant bacteria and maintain the effectiveness of TALICIA and other antibacterial drugs, it is strongly advised that TALICIA should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. In November 2019, the US FDA approved TALICIA in the US to treat H. pylori infection in adults.

Note: Further marketed drugs and their details will be provided in the report…

Emerging Drugs

Rifasutenizole (TNP-2198): TenNor Therapeutics

Rifasutenizole (TNP-2198) is a unique, multitargeting drug conjugate that through a synergistic mechanism of action, delivers potent bactericidal activities against drug-resistant H. pylori strains as well as an extremely low spontaneous resistance frequency. It has a wide range of applications in treating infections such as H. pylori infection, bacterial vaginosis, and Clostridium difficile infection.

TNP-2198 is supported by the National Major New Drug Innovation grant in China and has received IND approval and QIDP designation from the US FDA for the treatment of H. pylori infection patients. Furthermore, the company has completed five clinical trials in China and is currently conducting a multi-center, randomized, double-blind, bismuth-containing quadruple therapy controlled Phase III clinical trial in support of its New Drug Application in China and the US. This Phase III trial for TNP-2198 in the treatment of H. pylori infection is being carried out to explore an efficient, safe, and simplified eradication regimen that can seamlessly connect with a urea breath test (UBT). Furthermore, it offers the possibility to carry an H. pylori infection screening-eradication strategy on a large scale to prevent gastric cancer in populations with relatively high incidences of gastric cancer. Additionally, the drug candidate is also being investigated in a Phase II trial for Clostridioides difficile infection and bacterial vaginosis.

Drug Class Insights

The first line of defense against H. pylori infections is medications called Proton Pump Inhibitors (PPIs). These drugs work by significantly reducing the amount of acid produced by the stomach. This creates a less hospitable environment for the bacteria, making it difficult for them to survive. Omeprazole, lansoprazole, pantoprazole, rabeprazole, and esomeprazole are all commonly used PPIs.

However, PPIs alone aren't enough to eradicate H. pylori. Physicians typically prescribe a combination therapy that includes two or more antibiotics along with a PPI. The specific antibiotics chosen will depend on factors like local antibiotic resistance patterns and the patient's medical history. Some commonly used antibiotics for H. pylori include clarithromycin, amoxicillin, metronidazole, rifabutin, and tetracycline. Each class targets the bacteria in a different way, making it harder for them to develop resistance.

Antibacterial drugs, including clarithromycin, amoxicillin, metronidazole, and tetracycline, are vital in Helicobacter pylori eradication therapy. Clarithromycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, while amoxicillin disrupts cell wall synthesis by inhibiting transpeptidase enzymes. Metronidazole undergoes intracellular activation, damaging bacterial DNA and inhibiting nucleic acid synthesis, while tetracycline inhibits protein synthesis by binding to the 30S ribosomal subunit. These antibiotics collectively target H. pylori growth and replication.

Antisecretory drugs, particularly proton pump inhibitors (PPIs) like omeprazole and lansoprazole, complement antibacterial therapy by irreversibly inhibiting the H+/K+-ATPase proton pump on gastric parietal cells, reducing gastric acid secretion. Lowered gastric acidity enhances antibiotic activity against H. pylori and promotes healing of associated gastrointestinal mucosal damage, such as peptic ulcers and gastritis, by reducing acid-mediated tissue injury and inflammation. The combination of antibacterial and antisecretory drugs optimizes bacterial eradication and ulcer healing, leading to successful treatment outcomes in H. pylori infection.

TALICIA (RHB-105) marketed by RedHill Biopharma is an oral, all-in-one capsule with a three-drug combination of omeprazole, a PPI, amoxicillin, a penicillin-class antibacterial, and rifabutin, a rifamycin antibacterial, indicated for the treatment of H. pylori infection in adults. Omeprazole reduces gastric acid secretion, creating a favorable environment for antibiotics. Amoxicillin disrupts bacterial cell walls, leading to cell death, while rifabutin inhibits bacterial RNA synthesis. This triple therapy approach addresses bacterial growth, reduces gastric acidity, and targets antibiotic resistance, offering a promising treatment option for H. pylori infection.

TAKECAB (vonoprazan) or TAK-438, developed by Takeda, is an antisecretory drug targeting acid-related diseases like Helicobacter pylori infection. It belongs to the class of potassium-competitive acid blockers (P-CABs), which operate through a unique mechanism by competitively inhibiting the binding of potassium ions to H+, K+ ATPase in gastric parietal cells, disrupting the final step of gastric acid secretion. By effectively blocking this process, TAKECAB provides potent and sustained inhibition of acid secretion. This mechanism differs from traditional proton pump inhibitors (PPIs), offering a potentially more robust and prolonged antisecretory effect.

Helicobacter pylori Infection Market Outlook

H. pylori infection is one of the most common chronic bacterial infections worldwide, infecting approximately half of the global population. It is a spiral-shaped, flagellated gram-negative bacterium colonizing the human stomach that usually infects the stomach and small intestine. Usually acquired during childhood, it is the strongest known risk factor for non-cardia gastric adenocarcinoma, the most prevalent form of gastric cancer, and is also linked to peptic ulcer disease. With no single accurate diagnostic tool or method, the current diagnosis depends on both invasive and noninvasive methods. The treatment regime has seen many changes, with H. pylori infection designated as a Class I carcinogen by WHO and a Qualifying Pathogen under the US FDA GAIN Act.

The first effective therapy for H. pylori infection was introduced in the 1980s; since then, there have been major changes. The current treatment regime for H. pylori infection is therapeutic and not prophylactic; the goal is to eradicate the bacteria, as eradication alone is paramount for healing associated peptic ulcers and preventing relapses. But the growing prevalence of antibiotic resistance has made it a global challenge.

Most treatment guidelines recommend triple therapies, a combination of antibiotics with either antisecretories or PPIs or other acid-regulating agents, as the first line of treatment for eradicating H. pylori. Monotherapies prove ineffective as stomach acidity reduces the efficacy of antibiotics. Moreover, increasing antibiotic resistance has added to the troubles with only a few antibiotics active against H. pylori, including clarithromycin, amoxicillin, metronidazole, fluoroquinolone (levofloxacin, norfloxacin), tetracycline, and rifabutin.

It is important to understand that current guidelines advocate that choosing H. pylori infection eradication therapy should be based on the knowledge of the regional prevalence of clarithromycin antibiotic resistance and according to the local needs as such factors broadly impact the infection. There is a regional variation among approved therapies, with different ones being approved in different countries at different times.

RedHill Biopharma’s TALICIA an approved rifabutin-based therapy is prescribed widely as the second-line therapy. With an 8-year market exclusivity, it may prove to be a game changer for individuals with clarithromycin and metronidazole resistance.

Another drug to look out for will be Phathom Pharmaceuticals, P-CAB combination, and VOQUEZNA. Available as triple and dual pak, the drug was approved in 2022 by the US FDA and recently was reformulated and launched in the US in 2023.

Although antibiotic resistance rates have increased in the last decade and reduced the efficacy of recommended treatments. However, due to the guideline update and designation, the H pylori treatment landscape has also seen many FDA approvals. With a restrictive emerging pipeline for H. pylori, where there are limited novel mid or late-stage therapies and most trials are limited to improvements in combinations already approved the market for H. pylori is projected to witness some changes upon the entry of TenNor Therapeutics’ rifasutenizole (TNP-2198) during the forecast period.

Continued in report…

The current market segmentation is based on the therapies prescribed. Various marketed products for H. pylori infection include TALICIA, VOQUEZNA, approved only in the US OMECLAMOX-Pak, PYLERA in the US and EU, VONOSAP, VONOPION, TAKECAB, RABECURE, and RABEFINE in Japan only. These are the major segments covered in the forecast model. Several key players are evaluating their lead candidates in different stages of clinical development like rifasutenizole (TNP-2198).

The market for Helicobacter pylori Infection is expected to experience positive growth.
  • The total market size of Helicobacter pylori Infection in the 7MM was approximately USD 2.67 billion in 2022 and is projected to increase during the forecast period (2023-2034).
  • The market size of Helicobacter pylori Infection in the US was approximately USD 1.06 billion in 2022, which is anticipated to increase due to the increasing awareness of the disease and the launch of the emerging therapy.
  • The total market size of EU4 and the UK was calculated to be approximately USD 1.02 billion in 2022, which was nearly 38% of the total market revenue for the 7MM.
  • According to the analyst's estimates, among EU4 and the UK, France accounted for the highest market with approximately USD 237.3 million in 2022, followed by Germany with approximately USD 221.2 million in the respective year, while the UK accounted for the lowest market in 2022.
  • According to the analyst's analysis, in the US, among the currently used therapies, the second highest market share was of clarithromycin-based triple therapy, with a revenue of approximately USD 351.0 million, in 2022.
  • In 2022, Japan with a revenue of approximately USD 579.4 million, accounted for the second-highest market size of Helicobacter pylori Infection among the 7MM, which is expected to increase significantly by 2034.

Helicobacter pylori Infection Drugs Uptake

This section focuses on the uptake rate of potential drugs expected to be launched in the market during 2020-2034. For example, TenNor Therapeutics’ Rifasutenizole (TNP-2198), an investigational stable conjugate of rifamycin, is projected to be the first and only US FDA-approved, on-label, responsibly priced drug, with a medium uptake, will enter the US market in 2027.

Helicobacter pylori Infection Pipeline Development Activities

The report provides insights into different therapeutic candidates in Phase III, Phase II, and Phase I. It also analyzes key players involved in developing targeted therapeutics.

Pipeline development activities

The report covers information on collaborations, acquisitions and mergers, licensing, and patent details for emerging therapies for Helicobacter pylori infection.

KOL Views

To keep up with current market trends, we take KOLs and SMEs’ opinions working in the domain through primary research to fill the data gaps and validate our secondary research. Industry Experts contacted for insights on Helicobacter pylori infection evolving treatment landscape, patient reliance on conventional therapies, patient therapy switching acceptability, and drug uptake, along with challenges related to accessibility, including Medical/scientific writers, Medical Professionals, Professors, Directors, and Others.

The analysts connected with 50+ KOLs to gather insights; however, interviews were conducted with 15+ KOLs in the 7MM. Centers like the Stanford University School of Medicine, University of Cardiff, UK, German Institute of Human Nutrition (DIFE) Potsdam-Rehbrücke, Arthur Schubert Strasse, University of Poitiers, France, Aichi Medical University School of Medicine, Okayama Medical Center, Okayama were contacted. Their opinion helps understand and validate current and emerging therapy treatment patterns or Helicobacter pylori infection market trends. This will support the clients in potential upcoming novel treatments by identifying the overall scenario of the market and the unmet needs.

Physician’s View

According to our primary research analysis, current treatment scenarios for Helicobacter pylori infection typically involve a combination of antibiotics and proton pump inhibitors (PPIs) or other acid-reducing agents. The most common first-line treatment is triple therapy, which includes a PPI along with two antibiotics such as clarithromycin and amoxicillin or metronidazole. However, due to increasing antibiotic resistance, especially to clarithromycin, alternative regimens may be necessary, such as quadruple therapy with a bismuth salt, a PPI, and two antibiotics (usually metronidazole and tetracycline). Sequential therapy and concomitant therapy are other options, involving a combination of antibiotics and PPIs administered over different time frames.

According to a KOL in the US, despite being widely available, noninvasive testing for active H. pylori infection is still not routinely employed in practice. Many doctors worry that decreasing eradication rates may result in less successful treatment. Despite this, it is still normal practice to utilize triple regimens that contain a PPI and clarithromycin

Another KOL in Germany found that H. pylori infections are typically acquired in children. There are currently 20-30 million H. pylori infections in Germany, with a number of these infections leading to consequences like stomach cancer and ulcers.

Qualitative Analysis

We perform Qualitative and market Intelligence analysis using various approaches, such as SWOT and Conjoint Analysis. In the SWOT analysis, strengths, weaknesses, opportunities, and threats in terms of disease diagnosis, patient awareness, patient burden, competitive landscape, cost-effectiveness, and geographical accessibility of therapies are provided. These pointers are based on the Analyst’s discretion and assessment of the patient burden, cost analysis, and existing and evolving treatment landscape.

Conjoint Analysis analyzes multiple emerging therapies based on relevant attributes such as safety, efficacy, frequency of administration, route of administration, and order of entry. Scoring is given based on these parameters to analyze the effectiveness of therapy.

Further, the therapies’ safety is evaluated wherein the adverse events are majorly observed, and it sets a clear understanding of the side effects posed by the drug in the trials, which directly affects the safety of the molecule in the upcoming trials. It sets a clear understanding of the side effects posed by the drug in the trials. In addition, the scoring is also based on the route of administration, order of entry and designation, probability of success, and the addressable patient pool for each therapy. According to these parameters, the final weightage score and the ranking of the emerging therapies are decided.

Market Access and Reimbursement

The high cost of therapies for the treatment is a major factor restraining the growth of the drug market. Because of the high cost, the economic burden is increasing, leading the patient to escape from proper treatment.

The reimbursement challenges related to medical care and treatment for individuals with Helicobacter pylori Infection can be significant as it often requires specialized medical attention, covering the costs of diagnosis, treatment, and ongoing care. Health insurance plans may not fully cover limited coverage of some medical treatments, and therapies specific to Helicobacter pylori Infection. This can result in high out-of-pocket expenses for families seeking the best care for their loved ones. Moreover, it requires specialized care from healthcare providers with expertise. Finding and accessing such specialists may be challenging, and the associated costs may not always be fully reimbursed by insurance.


The report provides detailed insights on the country-wise accessibility and reimbursement scenarios, cost-effectiveness scenarios, programs making accessibility easier and out-of-pocket costs more affordable, insights on patients insured under federal or state government prescription drug programs, etc.

Scope of the Report

  • The report covers a segment of key events, an executive summary, and a descriptive overview of Helicobacter pylori Infection, explaining its causes, signs and symptoms, pathogenesis, and currently available therapies.
  • Comprehensive insight into the epidemiology segments and forecasts, the future growth potential of diagnosis rate, disease progression, and treatment guidelines have been provided.
  • Additionally, an all-inclusive account of the current and emerging therapies and the elaborative profiles of late-stage and prominent therapies will impact the current treatment landscape.
  • A detailed review of the Helicobacter pylori Infection, historical and forecasted market size, market share by therapies, detailed assumptions, and rationale behind our approach is included in the report, covering the 7MM drug outreach.
  • The report provides an edge while developing business strategies by understanding trends through SWOT analysis and expert insights/KOL views, patient journey, and treatment preferences that help shape and drive the 7MM Helicobacter pylori Infection market.

Helicobacter pylori Infection Report Insights

  • Patient Population
  • Therapeutic Approaches
  • Helicobacter pylori Infection Pipeline Analysis
  • Helicobacter pylori Infection Market Size and Trends
  • Existing and Future Market Opportunity

Helicobacter pylori Infection Report Key Strengths

  • 12 years Forecast
  • The 7MM Coverage
  • Helicobacter pylori Infection Epidemiology Segmentation
  • Key Cross Competition
  • Attribute analysis
  • Drugs Uptake and Key Market Forecast Assumptions

Helicobacter pylori Infection Report Assessment

  • Current Treatment Practices
  • Unmet Needs
  • Pipeline Product Profiles
  • Market Attractiveness
  • Qualitative Analysis (SWOT and Conjoint Analysis)

Key Questions

Market Insights

  • What was the total market size of Helicobacter pylori Infection, the market size of Helicobacter pylori Infection by therapies, and market share (%) distribution in 2020, and what would it look like by 2034? What are the contributing factors for this growth?
  • How will rifasutenizole (TNP-2198) affect the treatment paradigm of Helicobacter pylori Infection?
  • How will TALICIA, VOQUEZNA TRIPLE PAK and VOQUEZNA DUAL PAK compete with upcoming products and marketed therapies?
  • Which drug is going to be the largest contributor by 2034?
  • What are the pricing variations among different geographies for approved and marketed therapies?
  • How would future opportunities affect the market dynamics and subsequent analysis of the associated trends?

Epidemiology Insights

  • What are the disease risks, burdens, and unmet needs of Helicobacter pylori Infection? What will be the growth opportunities across the 7MM with respect to the patient population pertaining to Helicobacter pylori Infection?
  • What is the historical and forecasted Helicobacter pylori Infection patient pool in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan?
  • Out of the countries mentioned above, which country would have the highest diagnosed prevalent Helicobacter pylori Infection population during the forecast period (2023-2034)?
  • What factors are contributing to the growth of Helicobacter pylori Infection cases?

Current Treatment Scenario, Marketed Drugs, and Emerging Therapies

  • What are the current options for the treatment of Helicobacter pylori Infection? What are the current clinical and treatment guidelines for treating Helicobacter pylori Infection?
  • How many companies are developing therapies for the treatment of Helicobacter pylori Infection?
  • How many emerging therapies are in the mid-stage and late stage of development for treating Helicobacter pylori Infection?
  • What are the recent novel therapies, targets, mechanisms of action, and technologies developed to overcome the limitations of existing therapies?
  • What is the cost burden of current treatment on the patient?
  • Patient acceptability in terms of preferred treatment options as per real-world scenarios?
  • What are the accessibility issues of approved therapy in the US?
  • What is the 7MM historical and forecasted market of Helicobacter pylori Infection?

Reasons to Buy

  • The report will help develop business strategies by understanding the latest trends and changing treatment dynamics driving the Helicobacter pylori Infection market.
  • Insights on patient burden/disease prevalence, evolution in diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.
  • Understand the existing market opportunities in varying geographies and the growth potential over the coming years.
  • The distribution of historical and current patient share is based on real-world prescription data in the US, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.
  • Identifying upcoming solid players in the market will help devise strategies to help get ahead of competitors.
  • Detailed analysis and ranking of class-wise potential current and emerging therapies under the conjoint analysis section to provide visibility around leading classes.
  • Highlights of Access and Reimbursement policies for Helicobacter pylori Infection, barriers to accessibility of approved therapy, and patient assistance programs.
  • To understand Key Opinion Leaders’ perspectives around the accessibility, acceptability, and compliance-related challenges of existing treatment to overcome barriers in the future.
  • Detailed insights on the unmet needs of the existing market so that the upcoming players can strengthen their development and launch strategy.

Table of Contents

1. Key Insights2. Report Introduction
3. Parkinson's Disease Market Overview at a Glance
3.1. Market Share (%) Distribution of Parkinson's Disease in 2020
3.2. Market Share (%) Distribution of Parkinson's Disease in 2034
4. Methodology of Parkinson's Disease Epidemiology and Market5. Executive Summary of Parkinson's Disease6. Key Events
7. Disease Background and Overview
7.1. Introduction
7.2. Classification
7.3. Signs and Symptoms
7.4. Risk Factors
7.5. Pathophysiology
7.6. Diagnosis
7.6.1. Biomarker
7.6.2. Diagnostic Guidelines
7.6.2.1. American Academy of Family Physicians
7.6.2.2. European Federation of Neurological Societies/Movement Disorder Society- European Section (Efns/Mds-Es) Recommendations for the Diagnosis of Parkinson's Disease
7.6.2.3. the National Institute for Health and Care Excellence (Nice): Recommendation for Diagnosis of Parkinson's Disease
7.6.2.4. Movement Disorder Society (Mds) Clinical Diagnostic Criteria for Parkinson's Disease
7.6.3. Diagnostic Algorithm
7.6.4. Differential Diagnosis
7.7. Treatment
7.7.1. Treatment Algorithm
7.7.2. Treatment Guidelines
7.7.2.1. National Institute for Health and Care Excellence (Nice): Recommendation for Parkinson's Disease
7.7.2.2. American Academy of Neurology (Aan) Guidelines for Treatment of Early Parkinson's Disease
7.7.2.3. Clinical Practice Guidelines by the Nhs Spain
7.7.2.4. Clinical Practice Guidelines by the Japanese Society of Neurology (Jsn)
7.7.2.5. Guideline of the German Society for Neurology
8. Epidemiology and Patient Population
8.1. Key Findings
8.2. Assumptions and Rationale: The 7MM
8.2.1. Diagnosed Prevalent Cases of Parkinson's Disease
8.2.2. Gender-Specific Diagnosed Prevalent Cases of Parkinson's Disease
8.2.3. Age-Specific Diagnosed Prevalent Cases of Parkinson's Disease
8.2.4. Stage-Specific Diagnosed Prevalent Cases of Parkinson's Disease
8.2.5. Diagnosed Prevalent Cases of Psychosis in Parkinson's Disease
8.2.6. Diagnosed Prevalent Cases of Mci due to Parkinson's Disease
8.3. Total Diagnosed Prevalent Cases of Parkinson's Disease in the 7MM
8.4. the United States
8.4.1. Total Diagnosed Prevalent Cases of Parkinson's Disease in the US
8.4.2. Gender-Specific Diagnosed Prevalent Cases of Parkinson's Disease in the US
8.4.3. Age-Specific Diagnosed Prevalent Cases of Parkinson's Disease in the US
8.4.4. Stage-Specific Diagnosed Prevalent Cases of Parkinson's Disease in the US
8.4.5. Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in the US
8.4.6. Diagnosed Prevalent Cases of Mci due to Parkinson's Disease in the US
8.5. EU4 and the UK
8.5.1. Germany
8.5.1.1. Total Diagnosed Prevalent Cases of Parkinson's Disease in Germany
8.5.1.2. Gender-Specific Diagnosed Prevalent Cases of Parkinson's Disease in Germany
8.5.1.3. Age-Specific Diagnosed Prevalent Cases of Parkinson's Disease in Germany
8.5.1.4. Stage-Specific Diagnosed Prevalent Cases of Parkinson's Disease in Germany
8.5.1.5. Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in Germany
8.5.1.6. Diagnosed Prevalent Cases of Mci due to Parkinson's Disease in Germany
8.5.2. France
8.5.2.1. Total Diagnosed Prevalent Cases of Parkinson's Disease in France
8.5.2.2. Gender-Specific Diagnosed Prevalent Cases of Parkinson's Disease in France
8.5.2.3. Age-Specific Diagnosed Prevalent Cases of Parkinson's Disease in France
8.5.2.4. Stage-Specific Diagnosed Prevalent Cases of Parkinson's Disease in France
8.5.2.5. Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in France
8.5.2.6. Diagnosed Prevalent Cases of Mci due to Parkinson's Disease in France
8.5.3. Italy
8.5.3.1. Total Diagnosed Prevalent Cases of Parkinson's Disease in Italy
8.5.3.2. Gender-Specific Diagnosed Prevalent Cases of Parkinson's Disease in Italy
8.5.3.3. Age-Specific Diagnosed Prevalent Cases of Parkinson's Disease in Italy
8.5.3.4. Stage-Specific Diagnosed Prevalent Cases of Parkinson's Disease in Italy
8.5.3.5. Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in Italy
8.5.3.6. Diagnosed Prevalent Cases of Mci due to Parkinson's Disease in Italy
8.5.4. Spain
8.5.4.1. Total Diagnosed Prevalent Cases of Parkinson's Disease in Spain
8.5.4.2. Gender-Specific Diagnosed Prevalent Cases of Parkinson's Disease in Spain
8.5.4.3. Age-Specific Diagnosed Prevalent Cases of Parkinson's Disease in Spain
8.5.4.4. Stage-Specific Diagnosed Prevalent Cases of Parkinson's Disease in Spain
8.5.4.5. Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in Spain
8.5.4.6. Diagnosed Prevalent Cases of Mci due to Parkinson's Disease in Spain
8.5.5. the United Kingdom
8.5.5.1. Total Diagnosed Prevalent Cases of Parkinson's Disease in the UK
8.5.5.2. Gender-Specific Diagnosed Prevalent Cases of Parkinson's Disease in the UK
8.5.5.3. Age-Specific Diagnosed Prevalent Cases of Parkinson's Disease in the UK
8.5.5.4. Stage-Specific Diagnosed Prevalent Cases of Parkinson's Disease in the UK
8.5.5.5. Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in the UK
8.5.5.6. Diagnosed Prevalent Cases of Mci due to Parkinson's Disease in the UK
8.6. Japan
8.6.1. Total Diagnosed Prevalent Cases of Parkinson's Disease in Japan
8.6.2. Gender-Specific Diagnosed Prevalent Cases of Parkinson's Disease in Japan
8.6.3. Age-Specific Diagnosed Prevalent Cases of Parkinson's Disease in Japan
8.6.4. Stage-Specific Diagnosed Prevalent Cases of Parkinson's Disease in Japan
8.6.5. Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in Japan
8.6.6. Diagnosed Prevalent Cases of Mci due to Parkinson's Disease in Japan
9. Patient Journey
10. Marketed Therapies
10.1. Key Cross Competition of Marketed Drugs
10.2. Xadago/Equfina (Safinamide): Newron Pharmaceuticals/ Zambon/Supernus Pharmaceuticals/Eisai
10.2.1. Product Description
10.2.2. Regulatory Milestones
10.2.3. Other Development Activities
10.2.4. Clinical Trial Information
10.2.5. Safety and Efficacy
10.3. Nourianz/Nouriast (Istradefylline): Kyowa Kirin
10.3.1. Product Description
10.3.2. Regulatory Milestones
10.3.3. Other Development Activities
10.3.4. Clinical Trial Information
10.3.5. Safety and Efficacy
10.4. Duopa/Duodopa (Carbidopa and Levodopa-Es): Abbvie
10.4.1. Production Description
10.4.2. Regulatory Milestones
10.4.3. Other Development Activities
10.4.4. Clinical Trial Information
10.4.5. Safety and Efficacy
10.5. Inbrija (Levodopa): Acorda Therapeutics/Esteve Pharmaceuticals
10.5.1. Production Description
10.5.2. Regulatory Milestones
10.5.3. Other Development Activities
10.5.4. Clinical Trial Information
10.5.5. Safety and Efficacy
10.6. Gocovri (Amantadine): Supernus Pharmaceuticals
10.6.1. Product Description
10.6.2. Other Development Activities
10.6.3. Regulatory Milestones
10.6.4. Clinical Trial Information
10.6.5. Safety and Efficacy
10.7. Ongentys (Opicapone): Neurocrine Biosciences/Bial/Ono Pharmaceutical
10.7.1. Product Description
10.7.2. Regulatory Milestones
10.7.3. Other Development Activities
10.7.4. Clinical Trial Information
10.7.5. Safety and Efficacy
10.8. Haruropi Tape (Ropinirole Hcl): Hisamitsu Pharmaceutical/Kyowa Kirin
10.8.1. Production Description
10.8.2. Regulatory Milestones
10.8.3. Other Development Activities
10.8.4. Safety and Efficacy
10.9. Neupro/ Rotigotine Transdermal: Ucb
10.9.1. Product Description
10.9.2. Regulatory Milestone
10.9.3. Other Development Activities
10.9.4. Safety and Efficacy
10.1. Rytary (Carbidopa and Levodopa): Amneal Pharmaceuticals
10.10.1. Product Description
10.10.2. Regulatory Milestone
10.10.3. Other Development Activities
10.10.4. Clinical Trial Information
10.10.5. Safety and Efficacy
10.11. Abbv951/ Produodopa/ Vyalev (Foscarbidopa/ Foslevodopa): Abbvie
10.11.1. Product Description
10.11.2. Regulatory Milestone
10.11.3. Other Development Activities
10.11.4. Clinical Trials Information
10.11.5. Safety and Efficacy
10.12. Crexont/Ipx203: Amneal Pharmaceuticals
10.12.1. Product Description
10.12.2. Regulatory Milestone
10.12.3. Other Development Activities
10.12.4. Clinical Trial Information
10.12.5. Safety and Efficacy
11. Emerging Drug Profiles
11.1. Key Cross Competition
11.2. Solengepras (Cvn424): Cerevance
11.2.1. Product Description
11.2.2. Other Developmental Activities
11.2.3. Clinical Trials Information
11.2.4. Safety and Efficacy
11.2.5. Analyst Views
11.3. Minzasolmin (Ucb0599): Ucb Biopharma Srl/Novartis
11.3.1. Product Description
11.3.2. Other Developmental Activities
11.3.3. Clinical Trials Information
11.3.4. Safety and Efficacy
11.3.5. Analyst Views
11.4. Buntanetap (Anvs401/Posiphen): Annovis Bio
11.4.1. Product Description
11.4.2. Other Development Activities
11.4.3. Clinical Trial Information
11.4.4. Safety and Efficacy
11.4.5. Analyst Views
11.5. Spn-830 (Apomorphine Infusion): Supernus Pharmaceuticals, Inc./ Britannia Pharmaceutical
11.5.1. Product Description
11.5.2. Other Development Activities
11.5.3. Clinical Trials Information
11.5.4. Safety and Efficacy
11.5.5. Analyst Views
11.6. P2B001 (Extended-Release Pramipexole and Rasagiline): Pharma Two B
11.6.1. Product Description
11.6.2. Other Development Activities
11.6.3. Clinical Trials Information
11.6.4. Safety and Efficacy
11.6.5. Analyst Views
11.7. Nd0612 (Levodopa/Carbidopa): Mitsubishi Tanabe Pharma (Neuroderm)
11.7.1. Product Description
11.7.2. Other Development Activities
11.7.3. Clinical Trials Information
11.7.4. Safety and Efficacy
11.7.5. Analyst Views
11.8. Tavapadon: Abbvie/Cerevel Therapeutics, LLC
11.8.1. Product Description
11.8.2. Other Development Activities
11.8.3. Clinical Trial Information
11.8.4. Safety and Efficacy
11.8.5. Analyst Views
12. Parkinson's Disease: Market Analysis
12.1. Key Findings
12.2. Market Outlook
12.3. Key Market Forecast Assumptions
12.4. Conjoint Analysis
12.5. Total Market Size of Parkinson's Disease in the 7MM
12.6. Market Size of Parkinson's Disease by Therapies in the 7MM
12.7. Market Size of Parkinson's Disease in the United States
12.7.1. Total Market Size of Parkinson's Disease
12.7.2. Market Size of Parkinson's Disease by Therapies in the United States
12.8. Market Size of Parkinson's Disease in EU4 and the UK
12.8.1. Market Size of Parkinson's Disease in Germany
12.8.1.1. Total Market Size of Parkinson's Disease
12.8.1.2. Market Size of Parkinson's Disease by Therapies in Germany
12.8.2. Market Size of Parkinson's Disease in France
12.8.2.1. Total Market Size of Parkinson's Disease
12.8.2.2. Market Size of Parkinson's Disease by Therapies in France
12.8.3. Market Size of Parkinson's Disease in Italy
12.8.3.1. Total Market Size of Parkinson's Disease
12.8.3.2. Market Size of Parkinson's Disease by Therapies in Italy
12.8.4. Market Size of Parkinson's Disease in Spain
12.8.4.1. Total Market Size of Parkinson's Disease
12.8.4.2. Market Size of Parkinson's Disease by Therapies in Spain
12.8.5. Market Size of Parkinson's Disease in the UK
12.8.5.1. Total Market Size of Parkinson's Disease
12.8.5.2. Market Size of Parkinson's Disease by Therapies in the UK
12.9. Market Size of Parkinson's Disease in Japan
12.9.1. Total Market Size of Parkinson's Disease
12.9.2. Market Size of Parkinson's Disease by Therapies in Japan
13. Key Opinion Leaders’ Views14. SWOT Analysis15. Unmet Needs
16. Market Access and Reimbursement
16.1. the United States
16.1.1. Center for Medicare and Medicaid Services (CMS)
16.2. in EU4 and the UK
16.2.1. Germany
16.2.2. France
16.2.3. Italy
16.2.4. Spain
16.2.5. the United Kingdom
16.3. Japan
16.3.1. Mhlw
17. Appendix
17.1. Bibliography
17.2. Acronyms and Abbreviations
17.3. Report Methodology
18. Publisher Capabilities19. Disclaimer20. About the Publisher
List of Tables
Table 1: Summary of Market and Epidemiology (2020-2034)
Table 2: Key Events for Parkinson’s Disease
Table 3: Signs and Symptoms of Parkinson’s Disease
Table 4: Differential Diagnosis of Parkinsonism (1/2)
Table 5: Differential Diagnosis of Parkinsonism (2/2)
Table 6: Potential Benefits and Harms of Dopamine Agonists, Levodopa, and MAO B inhibitors
Table 7: Potential Benefits and Harms of Dopamine Agonists, COMT Inhibitors, and Amantadine
Table 8: Pharmacological Management of Non-motor Symptoms (1/2)
Table 9: Pharmacological Management of Non-motor Symptoms (2/2)
Table 10: Nonpharmacological Management of Motor and Non-motor Symptoms (1/2)
Table 11: Nonpharmacological Management of Motor and Non-motor Symptoms (2/2)
Table 12: AAN Guidelines for the Treatment of Early Parkinson’s Disease (1/2)
Table 13: AAN Guidelines for the Treatment of Early Parkinson’s Disease (2/2)
Table 14: NHS Spain - Motor Symptoms Recommendations for Treatment of Parkinson’s Disease
Table 15: NHS Spain - Non-motor Symptoms Recommendations for Treatment of Parkinson’s Disease
Table 16: NHS Spain - Recommendations for Treatment of Parkinson’s Disease (Non-pharmacological)
Table 17: Recommendations for Treatment of Parkinson’s Disease - Speech Therapy
Table 18: Recommendations for Treatment of Parkinson’s Disease - Nutrition and Diet
Table 19: Recommendations for Treatment of Parkinson’s Disease by JSN - 2011 Update (1/2)
Table 20: Recommendations for Treatment of Parkinson’s Disease by JSN - 2011 Update (2/2)
Table 21: Total Diagnosed Prevalent Cases of Parkinson’s Disease in the 7MM (2020-2034)
Table 22: Total Diagnosed Prevalent Cases of Parkinson’s Disease in the US (2020-2034)
Table 23: Gender-specific Diagnosed Prevalent Cases of Parkinson’s Disease in the US (2020-2034)
Table 24: Age-specific Diagnosed Prevalent Cases of Parkinson’s Disease in the US (2020-2034)
Table 25: Stage-specific Diagnosed Prevalent Cases of Parkinson’s Disease in the US (2020-2034)
Table 26: Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in the US (2020-2034)
Table 27: Diagnosed Prevalent Cases of MCI due to Parkinson's Disease in the US (2020-2034)
Table 28: Total Diagnosed Prevalent Cases of Parkinson’s Disease in EU4 and the UK (2020-2034)
Table 29: Gender-specific Diagnosed Prevalent Cases of Parkinson’s Disease in EU4 and the UK (2020-2034)
Table 30: Age-specific Diagnosed Prevalent Cases of Parkinson’s Disease in EU4 and the UK (2020-2034)
Table 31: Stage-specific Diagnosed Prevalent Cases of Parkinson’s Disease in EU4 and the UK (2020-2034)
Table 32: Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in EU4 and the UK (2020-2034)
Table 33: Diagnosed Prevalent Cases of MCI due to Parkinson's Disease in EU4 and the UK (2020-2034)
Table 34: Total Diagnosed Prevalent Cases of Parkinson’s Disease in Germany (2020-2034)
Table 35: Gender-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Germany (2020-2034)
Table 36: Age-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Germany (2020-2034)
Table 37: Stage-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Germany (2020-2034)
Table 38: Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in Germany (2020-2034)
Table 39: Diagnosed Prevalent Cases of MCI due to Parkinson's Disease in Germany (2020-2034)
Table 40: Total Diagnosed Prevalent Cases of Parkinson’s Disease in France (2020-2034)
Table 41: Gender-specific Diagnosed Prevalent Cases of Parkinson’s Disease in France (2020-2034)
Table 42: Age-specific Diagnosed Prevalent Cases of Parkinson’s Disease in France (2020-2034)
Table 43: Stage-specific Diagnosed Prevalent Cases of Parkinson’s Disease in France (2020-2034)
Table 44: Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in France (2020-2034)
Table 45: Diagnosed Prevalent Cases of MCI due to Parkinson's Disease in France (2020-2034)
Table 46: Total Diagnosed Prevalent Cases of Parkinson’s Disease in Italy (2020-2034)
Table 47: Gender-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Italy (2020-2034)
Table 48: Age-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Italy (2020-2034)
Table 49: Stage-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Italy (2020-2034)
Table 50: Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in Italy (2020-2034)
Table 51: Diagnosed Prevalent Cases of MCI due to Parkinson's Disease in Italy (2020-2034)
Table 52: Total Diagnosed Prevalent Cases of Parkinson’s Disease in Spain (2020-2034)
Table 53: Gender-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Spain (2020-2034)
Table 54: Age-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Spain (2020-2034)
Table 55: Stage-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Spain (2020-2034)
Table 56: Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in Spain (2020-2034)
Table 57: Diagnosed Prevalent Cases of MCI due to Parkinson's Disease in Spain (2020-2034)
Table 58: Total Diagnosed Prevalent Cases of Parkinson’s Disease in the UK (2020-2034)
Table 59: Gender-specific Diagnosed Prevalent Cases of Parkinson’s Disease in the UK (2020-2034)
Table 60: Age-specific Diagnosed Prevalent Cases of Parkinson’s Disease in the UK (2020-2034)
Table 61: Stage-specific Diagnosed Prevalent Cases of Parkinson’s Disease in the UK (2020-2034)
Table 62: Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in the UK (2020-2034)
Table 63: Diagnosed Prevalent Cases of MCI due to Parkinson's Disease in the UK (2020-2034)
Table 64: Total Diagnosed Prevalent Cases of Parkinson’s Disease in Japan (2020-2034)
Table 65: Gender-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Japan (2020-2034)
Table 66: Age-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Japan (2020-2034)
Table 67: Stage-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Japan (2020-2034)
Table 68: Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in Japan (2020-2034)
Table 69: Diagnosed Prevalent Cases of MCI due to Parkinson's Disease in Japan (2020-2034)
Table 70: Comparison of Marketed Drugs
Table 71: XADAGO/EQUFINA (safinamide), Clinical Trial Description, 2024
Table 72: NOURIANZ/NOURIAST (istradefylline), Clinical Trial Description, 2024
Table 73: DUOPA/DUODOPA (carbidopa and levodopa-ES), Clinical Trial Description, 2024
Table 74: INBRIJA (levodopa), Clinical Trial Description, 2024
Table 75: GOCOVRI (amantadine), Clinical Trial Description, 2024
Table 76: ONGENTYS (opicapone), Clinical Trial Description, 2024
Table 77: RYTARY (carbidopa and levodopa), Clinical Trial Description, 2024
Table 78: ABBV-951 (foscarbidopa/foslevodopa), Clinical Trial Description, 2024
Table 79: IPX203, Clinical Trial Description, 2024
Table 80: Comparison of Emerging Drugs
Table 81: Solengepras (CVN424), Clinical Trial Description, 2024
Table 82: Minzasolmin (UCB0599), Clinical Trial Description, 2024
Table 83: Buntanetap (ANVS401/Posiphen), Clinical Trial Description, 2024
Table 84: SPN-830 (apomorphine infusion), Clinical Trial Description, 2024
Table 85: P2B001 (extended-release pramipexole and rasagiline), Clinical Trial Description, 2024
Table 86: ND0612 (levodopa/carbidopa), Clinical Trial Description, 2024
Table 87: Tavapadon, Clinical Trial Description, 2024
Table 88: Key Market Forecast Assumptions for SPN-830 (Apomorphine Infusion Pump)
Table 89: Key Market Forecast Assumptions for Tavapadon
Table 90: Key Market Forecast Assumptions for ABBV-951 (foscarbidopa/foslevodopa)
Table 91: Key Market Forecast Assumptions for CREXONT (carbidopa/levodopa extended-release)
Table 92: Key Market Forecast Assumptions for P2B001 (extended-release pramipexole and rasagiline)
Table 93: Key Market Forecast Assumptions for ND0612 (levodopa/carbidopa)
Table 94: Key Market Forecast Assumptions for Buntanetap (ANVS401/posiphen)
Table 95: Key Market Forecast Assumptions for Solengepras (CVN424)
Table 96: Key Market Forecast Assumptions for Minzasolmin (UCB0599)
Table 97: Total Market Size of Parkinson’s Disease in the 7MM (2020-2034)
Table 98: Market Size of Parkinson’s Disease by Therapies in the 7MM (2020-2034)
Table 99: Total Market Size of Parkinson’s Disease in the US (2020-2034)
Table 100: Market Size of Parkinson’s Disease by Therapies in the United States (2020-2034)
Table 101: Total Market Size of Parkinson’s Disease in EU4 and the UK (2020-2034)
Table 102: Market Size of Parkinson’s Disease by Therapies in EU4 and the UK (2020-2034)
Table 103: Total Market Size of Parkinson’s Disease in Germany (2020-2034)
Table 104: Market Size of Parkinson’s Disease by Therapies in Germany (2020-2034)
Table 105: Total Market Size of Parkinson’s Disease in France (2020-2034)
Table 106: Market Size of Parkinson’s Disease by Therapies in France (2020-2034)
Table 107: Total Market Size of Parkinson’s Disease in Italy (2020-2034)
Table 108: Market Size of Parkinson’s Disease by Therapies in Italy (2020-2034)
Table 109: Total Market Size of Parkinson’s Disease in Spain (2020-2034)
Table 110: Market Size of Parkinson’s Disease by Therapies in Spain (2020-2034)
Table 111: Total Market Size of Parkinson’s Disease in the UK (2020-2034)
Table 112: Market Size of Parkinson’s Disease by Therapies in the UK (2020-2034)
Table 113: Total Market Size of Parkinson’s Disease in Japan (2020-2034)
Table 114: Market Size of Parkinson’s Disease by Therapies in Japan (2020-2034)
List of Figures
Figure 1: Classification of Parkinson’s Disease
Figure 2: Clinical Manifestations in Parkinson’s Disease
Figure 3: Risk Factors Involved in Parkinson’s Disease
Figure 4: Genes Involved in Parkinson’s Disease
Figure 5: Mechanisms of Neurodegeneration in Parkinson’s Disease
Figure 6: QSBB Criteria for the Diagnosis of Parkinson’s Disease
Figure 7: MDS Clinical Diagnostic Criteria for Parkinson’s Disease
Figure 8: AAFP Diagnostic Algorithm for Parkinson’s Disease
Figure 9: Treatment for Parkinson’s Disease
Figure 10: Mechanism of Action of Levodopa
Figure 11: Dopamine Agonists for the Treatment of Parkinson’s Disease
Figure 12: Treatment Algorithm for Parkinson’s Disease
Figure 13: Total Diagnosed Prevalent Cases of Parkinson’s Disease in the 7MM (2020-2034)
Figure 14: Total Diagnosed Prevalent Cases of Parkinson’s Disease in the US (2020-2034)
Figure 15: Gender-specific Diagnosed Prevalent Cases of Parkinson’s Disease in the US (2020-2034)
Figure 16: Age-specific Diagnosed Prevalent Cases of Parkinson’s Disease in the US (2020-2034)
Figure 17: Stage-specific Diagnosed Prevalent Cases of Parkinson’s Disease in the US (2020-2034)
Figure 18: Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in the US (2020-2034)
Figure 19: Diagnosed Prevalent Cases of MCI due to Parkinson's Disease in the US (2020-2034)
Figure 20: Total Diagnosed Prevalent Cases of Parkinson’s Disease in EU4 and the UK (2020-2034)
Figure 21: Gender-specific Diagnosed Prevalent Cases of Parkinson’s Disease in EU4 and the UK (2020-2034)
Figure 22: Age-specific Diagnosed Prevalent Cases of Parkinson’s Disease in EU4 and the UK (2020-2034)
Figure 23: Stage-specific Diagnosed Prevalent Cases of Parkinson’s Disease in EU4 and the UK (2020-2034)
Figure 24: Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in EU4 and the UK (2020-2034)
Figure 25: Diagnosed Prevalent Cases of MCI due to Parkinson's Disease in EU4 and the UK (2020-2034)
Figure 26: Total Diagnosed Prevalent Cases of Parkinson’s Disease in Germany (2020-2034)
Figure 27: Gender-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Germany (2020-2034)
Figure 28: Age-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Germany (2020-2034)
Figure 29: Stage-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Germany (2020-2034)
Figure 30: Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in Germany (2020-2034)
Figure 31: Diagnosed Prevalent Cases of MCI due to Parkinson's Disease in Germany (2020-2034)
Figure 32: Total Diagnosed Prevalent Cases of Parkinson’s Disease in France (2020-2034)
Figure 33: Gender-specific Diagnosed Prevalent Cases of Parkinson’s Disease in France (2020-2034)
Figure 34: Age-specific Diagnosed Prevalent Cases of Parkinson’s Disease in France (2020-2034)
Figure 35: Stage-specific Diagnosed Prevalent Cases of Parkinson’s Disease in France (2020-2034)
Figure 36: Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in France (2020-2034)
Figure 37: Diagnosed Prevalent Cases of MCI due to Parkinson's Disease in France (2020-2034)
Figure 38: Total Diagnosed Prevalent Cases of Parkinson’s Disease in Italy (2020-2034)
Figure 39: Gender-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Italy (2020-2034)
Figure 40: Age-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Italy (2020-2034)
Figure 41: Stage-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Italy (2020-2034)
Figure 42: Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in Italy (2020-2034)
Figure 43: Diagnosed Prevalent Cases of MCI due to Parkinson's Disease in Italy (2020-2034)
Figure 44: Total Diagnosed Prevalent Cases of Parkinson’s Disease in Spain (2020-2034)
Figure 45: Gender-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Spain (2020-2034)
Figure 46: Age-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Spain (2020-2034)
Figure 47: Stage-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Spain (2020-2034)
Figure 48: Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in Spain (2020-2034)
Figure 49: Diagnosed Prevalent Cases of MCI due to Parkinson's Disease in Spain (2020-2034)
Figure 50: Total Diagnosed Prevalent Cases of Parkinson’s Disease in the UK (2020-2034)
Figure 51: Gender-specific Diagnosed Prevalent Cases of Parkinson’s Disease in the UK (2020-2034)
Figure 52: Age-specific Diagnosed Prevalent Cases of Parkinson’s Disease in the UK (2020-2034)
Figure 53: Stage-specific Diagnosed Prevalent Cases of Parkinson’s Disease in the UK (2020-2034)
Figure 54: Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in the UK (2020-2034)
Figure 55: Diagnosed Prevalent Cases of MCI due to Parkinson's Disease in the UK (2020-2034)
Figure 56: Total Diagnosed Prevalent Cases of Parkinson’s Disease in Japan (2020-2034)
Figure 57: Gender-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Japan (2020-2034)
Figure 58: Age-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Japan (2020-2034)
Figure 59: Stage-specific Diagnosed Prevalent Cases of Parkinson’s Disease in Japan (2020-2034)
Figure 60: Diagnosed Prevalent Cases of Psychosis due to Parkinson's Disease in Japan (2020-2034)
Figure 61: Diagnosed Prevalent Cases of MCI due to Parkinson's Disease in Japan (2020-2034)
Figure 62: Patient Journey
Figure 63: Total Market Size of Parkinson’s Disease in the 7MM (2020-2034)
Figure 64: Market Size of Parkinson’s Disease by Therapies in the 7MM (2020-2034)
Figure 65: Total Market Size of Parkinson’s Disease in the US (2020-2034)
Figure 66: Market Size of Parkinson’s Disease by Therapies in the United States (2020-2034)
Figure 67: Total Market Size of Parkinson’s Disease in EU4 and the UK (2020-2034)
Figure 68: Market Size of Parkinson’s Disease by Therapies in EU4 and the UK (2020-2034)
Figure 69: Total Market Size of Parkinson’s Disease in Germany (2020-2034)
Figure 70: Market Size of Parkinson’s Disease by Therapies in Germany (2020-2034)
Figure 71: Total Market Size of Parkinson’s Disease in France (2020-2034)
Figure 72: Market Size of Parkinson’s Disease by Therapies in France (2020-2034)
Figure 73: Total Market Size of Parkinson’s Disease in Italy (2020-2034)
Figure 74: Market Size of Parkinson’s Disease by Therapies in Italy (2020-2034)
Figure 75: Total Market Size of Parkinson’s Disease in Spain (2020-2034)
Figure 76: Market Size of Parkinson’s Disease by Therapies in Spain (2020-2034)
Figure 77: Total Market Size of Parkinson’s Disease in the UK (2020-2034)
Figure 78: Market Size of Parkinson’s Disease by Therapies in the UK (2020-2034)
Figure 79: Total Market Size of Parkinson’s Disease in Japan (2020-2034)
Figure 80: Market Size of Parkinson’s Disease by Therapies in Japan (2020-2034)
Figure 81: SWOT Analysis
Figure 82: Unmet Needs
Figure 83: Health Technology Assessment
Figure 84: Reimbursement Process in the United States
Figure 85: Reimbursement Process in Germany
Figure 86: Reimbursement Process in France
Figure 87: Reimbursement process in Italy
Figure 88: Reimbursement Process in Spain
Figure 89: Reimbursement Process in the United Kingdom
Figure 90: Reimbursement Process in Japan

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • UCB Biopharma SRL
  • Novartis
  • Annovis Bio
  • Supernus Pharmaceuticals, Inc.
  • Britannia Pharmaceutical
  • Pharma Two B
  • Mitsubishi Tanabe Pharma (NeuroDerm)
  • AbbVie
  • Cerevel Therapeutics, LLC