Table of Contents
Editorial Board and Reviewers viii
List of Contributors ix
Introduction xv
Section 1 - Cancer Causes, Prevention, and Early Detection 1
1 Descriptive Epidemiology 3
Rebecca L. Siegel, Kimberly D. Miller, and Ahmedin Jemal
2 Fundamentals of Cancer Epidemiology 15
Susan M. Gapstur and Eric J. Jacobs
3 Socioeconomic Inequalities in Cancer Incidence and Mortality 23
Gopal K. Singh and Ahmedin Jemal
4 The Global Burden of Cancer 33
Ahmedin Jemal and Lindsey A. Torre
5 Counseling and Testing for Inherited Predisposition to Cancer 45
Emily Glogowski, Kasmintan A. Schrader, Kelly L. Stratton, and Kenneth Offit
6 Tobacco 58
Thomas J. Glynn, Richard D. Hurt, and J. Lee Westmaas
7 Microbial Carcinogens 72
Edgar P. Simard and Ahmedin Jemal
8 Environmental and Occupational Carcinogens 81
Elizabeth Ward
9 Nutrition and Physical Activity for Cancer Prevention 92
Stacey Fedewa, Rebecca L. Siegel, Colleen Doyle, Marji L. McCullough, and Alpa V. Patel
10 Sun Protection 99
Andrew C. Walls and Martin A. Weinstock
11 Screening and Early Detection 110
Robert A. Smith, Otis W. Brawley, and Richard C. Wender
Section 2 - Cancer Biology 137
12 The Principles and Drivers of Cancer 139
Charles Saxe and William C. Phelps
Section 3 - Diagnosis 153
13 Imaging in Oncology 155
Andreas G. Wibmer, Andreas M. Hötker, Maura Miccò, David M. Panicek, and Hedvig Hricak
14 The Pathologic Evaluation of Neoplastic Diseases 164
John D. Pfeifer and Mark R. Wick
15 Cancer Staging 184
Frederick L. Greene and Lauren A. Kosinski
Section 4 - Treatment Modalities 191
16 Surgical Oncology Overview 193
M. Andrew Sicard and Benjamin D. Li
17 Radiotherapy 204
Curtiland Deville, Jr., Gaurav Shukla, Ramesh Rengan, and Charles R. Thomas, Jr.
18 Cytotoxic Chemotherapy 220
R. Donald Harvey and Fadlo R. Khuri
19 Hormonal Therapy for Cancer 236
Amelia B. Zelnak and Bradley C. Carthon
20 Immunotherapy of Cancer 244
Diwakar Davar, Ahmad A. Tarhini, and John M. Kirkwood
21 Targeted Therapies 267
Elizabeth Kessler, Paul Brittain, S. Lindsey Davis, Stephen Leong, S. Gail Eckhardt, and Christopher H. Lieu
22 Hematopoietic Stem Cell Transplantation for Cancer 284
Joshua F. Zeidner, Christopher G. Kanakry, and Leo Luznik
23 Diet, Physical Activity, and Weight Control for Cancer Patients and Survivors 293
Wendy DemarkÂ]Wahnefried, Laura Q. Rogers, Catherine M. Alfano, Cynthia A. Thomson, Kerry S. Courneya, Jeffrey A. Meyerhardt, Nicole L. Stout, Elizabeth Kvale, Heidi Ganzer, Ted Gansler, and Jennifer A. Ligibel
24 Clinical Trials 306
Olwen M. Hahn and Richard L. Schilsky
25 Complementary and Alternative (Integrative) Oncology 315
Gabriel Lopez, Richard Lee, M. Kay Garcia, Alejandro Chaoul, and Lorenzo Cohen
Section 5 - Geriatric Oncology 323
26 Geriatric Oncology 325
Arvind M. Shinde, Sumanta K. Pal, and Arti Hurria
Section 6 - Symptom Management, Palliative Care, Complications and Toxicities of Treatment, PatientÂ]Reported Outcomes, etc. 333
27 Palliative and Supportive Care 335
Rony Dev and Eduardo Bruera
28 Sexuality and Fertility 359
Jeanne Carter, Shari B. Goldfarb, Yukio Sonoda, Christian J. Nelson, Maura N. Dickler, and John P. Mulhall
29 Psychiatric Issues in Cancer Patients 379
Andrew J. Roth and Adrienne Jaeger
30 Oncologic Emergencies 393
Mark A. Lewis, William J. Hogan, and Timothy J. Moynihan
31 PatientÂ]Reported Outcomes in Cancer: Application and Utility in Clinical Practice and Research 409
Kevin D. Stein, Tenbroeck Smith, Joseph E. Bauer, Deborah L. Driscoll, and Dexter L. Cooper
32 Survivorship Care 419
Emily Tonorezos, Shrujal S. Baxi, Victoria Blinder, Darren R. Feldman, Danielle Novetsky Friedman, Matthew Matasar, Talya Salz, Armin Shahrokni, and Kevin C. Oeffinger
Index 437
