Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies offers thorough discussions on preconception carrier screening, genetic engineering and the use of CRISPR gene editing, mitochondrial gene replacement therapy, sex selection, predictive testing, secondary findings, embryo reduction and the moral status of the embryo, genetic enhancement, and the sharing of genetic data. Chapter contributions from leading bioethicists and clinicians encourage a global, holistic perspective on applied challenges and the moral questions relating the implementation of genetic reproductive technology. The book is an ideal resource for practitioners, regulators, lawmakers, clinical researchers, genetic counselors and graduate and medical students.
As the Human Genome Project has triggered a technological revolution that has influenced nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, prenatal genetic testing, and gene therapy, this book presents a timely resource.
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Table of Contents
1. Genomic Editing-From Human Health to the "Perfect Child
2. Ethics of Mitochondrial Gene Replacement Therapy
3. Reproductive Technologies Used by Same Gender Couples
4. Ethical Issues Raised by Multiparents
5. Revisiting the Nondirective Principle of Genetic Counseling in Prenatal Screening
6. Sex Selection, Gender Selection, and Sexism
7. The Impact of Big Data on Beginning of Life Issues
8. The Moral Status of the Embryo From the Standpoint of Social Perceptions
9. Fetal Reduction
10. Stem Cell Therapies for Neurodegenerative Disorders. An Ethical Analysis
11. Predictive Genetic Testing in Multifactorial Disorders
12. Whole-Genome Sequencing as a Method of Prenatal Genetic Diagnosis
13. Noninvasive Prenatal Genetic Diagnosis
14. Prenatal Testing in Low-Risk Populations: A US Perspective
15. Using Genetics for Enhancement (Liberal Eugenics)
16. Should Incidental Findings Arising From Prenatal Testing be Reported Indiscriminately to Patients?
17. Third Party Sharing of Genetic Information