Pathology of Melanocytic Tumors

Table of Contents

Section I Benign Cutaneous Melanocytic Proliferations

1. Melanotic Macules

2. Acquired Melanocytic Nevi

3. Congenital Melanocytic Nevi

4. Spitz Nevi

5. Blue Nevi and Dermal Melanocytosis

6. Deep Penetrating Nevi

7. Nevi of Special Cutaneous Sites

8. Traumatized and Recurrent Melanocytic Nevi, and Nevi Changing under Treatment

9. Combined Melanocytic Nevi

10. Pigmented Epithelioid Melanocytoma

Section II Primary Cutaneous Melanoma

11. Histopathologic Fiagnosis of Melanoma

12. Lentigo Maligna Melanoma

13. Superficial Spreading Melanoma

14. Acral and Subungual Melanoma

15. Nodular Melanoma

16. Desmoplastic Melanoma

17. Nevoid Melanoma

18. Spitzoid Melanoma

19. Melanoma Arising in Association with or Simulating a Blue Nevus

20. Uncommon Variants of Melanoma

21. Pediatric Melanoma

Section III Primary Extracutaneous Melanocytic Proliferations

22. Conjunctival Melanocytic Proliferations

23. Melanocytic Proliferations of the Uveal Tract

24. Mucosal Melanocytic Tumors

25. Primary Melanocytic Neoplasms of the Central Nervous System and Melanotic Schwannoma

26. Melanocytic nevi in Lymph Nodes

Section IV Metastatic Melanoma

27. Metastatic Melanoma

Section V Ancillary Studies

28. Dermoscopy for Dermatopathologists

29. Immunohistochemistry for the Diagnosis of Melanocytic Proliferations

30. Molecular Techniques

31. Clinical, Dermoscopic, Pathologic and Molecular Correlations

Section VI Prognosis, Staging, and Reporting of Melanoma

32. Prognosis, Staging, and Reporting of Melanoma

Section VII Margin Assessment of Melanomas

33. Margin Assessment of Cutaneous Melanoma

Authors

Klaus J. Busam Professor of Pathology and Laboratory Medicine, Weill Medical College of Cornell University; Director of Dermatopathology, Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA. Dr. Klaus Busam is a Professor of Pathology at Memorial Sloan Kettering Cancer Center and the Director of the combined Memorial Sloan Kettering/Cornell Dermatopathology Training Program. His training is from the Brigham & Women's Hospital and Harvard Medical School combined program. His interests include the utilization of clinical, histological and molecular diagnostic methods to optimize diagnostic accuracy and best predict the behavior of melanocytic neoplasms. As a dermatopathologist, he is recognized as an international expert in the diagnosis of melanoma and is sent many second opinion cases both from within and outside of the United States. As a researcher he is focused on developing molecular based methods to improve the diagnosis and prognostication of melanocytic neoplasms. He has authored over 250 peer reviewed journal articles and numerous textbooks in dermatopathology. Pedram Gerami Professor of Dermatology and Pathology, Director of the Skin Cancer Institute of Northwestern Medicine (SCIN-med) Director of the Melanoma Program of SCIN-med Northwestern University Department of Dermatology and the Lurie Cancer Center. Dr Pedram Gerami: Selected to Best Doctors in America 2019-2020, Dr Gerami is the director of the Skin Cancer Institute of Northwestern Medical Group (SCIN-Med) and the director of the Melanoma Program in the Skin Cancer Institute and the Melanoma clinic in the department of Dermatology. His clinical and research interests are primarily focused on melanoma skin cancer, atypical nevi and borderline melanocytic tumors such as Spitz tumors which may be difficult to classify. As a dermatologist, dermatopathologist and researcher focused in the care of patients with melanoma and atypical nevi, he has a unique perspective on the behavior of melanocytic neoplasms. Richard A Scolyer Co-Director of Research, Melanoma Institute Australia; Senior Staff Specialist,Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital; Clinical Professor, Sydney Medical School, The University of Sydney, Sydney, Australia.