2 Introduction
2.1 What Is This Report About?
2.2 Knee Reconstruction Market Segmentation
2.3 Definitions of Markets Covered in the Report
3 Knee Reconstruction Market, United States
3.1 Knee Reconstruction Market, United States, Revenue ($m), 2015-2025
3.1.1 Partial Knee Replacement Market, United States, Revenue ($m), by Segment, 2015-2025
3.1.2 Primary Knee Replacement Market, United States, Revenue ($m), by Segment, 2015-2025
3.2 Knee Reconstruction Market, United States, Volume (Units), 2015-2025
3.2.1 Partial Knee Replacement Market, United States, Volume (Units), by Segment, 2015-2025
3.2.2 Primary Knee Replacement Market, United States, Volume (Units), by Segment, 2015-2025
3.3 Knee Reconstruction Market, United States, Average Price ($), 2015-2025
3.4 Knee Reconstruction Market, United States, Distribution Share by Revenue ($m), 2017
3.5 Knee Reconstruction Market, United States, Company Share by Revenue ($m), 2017
4 Overview of Key Companies in United States, Knee Reconstruction Market
4.1 Zimmer Biomet Holdings Inc
4.1.1 Company Overview
4.2 DePuy Synthes Inc
4.2.1 Company Overview
4.3 Stryker Corp
4.3.1 Company Overview
4.4 Exactech Inc
4.4.1 Company Overview
4.5 Smith & Nephew Plc
4.5.1 Company Overview
4.6 MicroPort Scientific Corp
4.6.1 Company Overview
6 Financial Deals Landscape
6.1 Equity Offerings
6.1.1 Amedica Files Registration Statement for Rights Offering of Units for up to USD11.4 Million
6.1.2 ConforMIS Prices USD20 Million in Public Offering of Shares
6.2 Private Equity
6.2.1 TPG Capital Amends Agreement to Acquire Exactech
6.2.2 JANA Partners Denies Rumor to Acquire Certain Stake in Zimmer Biomet
6.3 Venture Financing
6.3.1 Active Implants Raises USD3.3 Million in Venture Financing
7 Recent Developments
7.1 Corporate Communications
7.1.1 May 14, 2018: OMNIlife science Appoints Rick Epstein as Chief Executive Officer
7.1.2 Apr 30, 2018: HSS Surgeon Michael L. Parks, MD, Named President of Orthopaedic Research and Education Foundation
7.1.3 Apr 05, 2018: ADAPT Pharma Welcomes Surgeon General Naloxone Advisory
7.1.4 Mar 19, 2018: Zimmer Biomet Appoints Coleman N. Lannum as Senior Vice President of Investor Relations
7.1.5 Mar 13, 2018: Orthofix Announces Appointment of John Sicard to Board of Directors
7.1.6 Mar 05, 2018: Orthopaedic Industry Veteran Jeffrey R. Binder Joins Bill Petty, MD, as Co-Executive Chairman of Exactech; Daniel Hann Joins Exactech as Sr. Vice President of Business Development
7.1.7 Mar 03, 2018: Arthrex Announces New Vice President of Strategic Development
7.1.8 Feb 20, 2018: Onconova Announces Presentation on its Acute Myeloid Leukemia Drug Candidate ON-150030 at 2018 American Chemical Society National Meeting and Expo
7.1.9 Dec 19, 2017: Zimmer Biomet Announces Appointment of Bryan C. Hanson as President and Chief Executive Officer
7.1.10 Dec 12, 2017: Stryker announces Mr. Howard E. Cox, Jr. will retire from Board of Directors
7.1.11 Dec 08, 2017: Micron Solutions Designates Mr. E. P. Marinos as a Director Emeritus and Appoints Mr. Andrei Soran to its Board of Directors
7.1.12 Sep 26, 2017: Pharming Group and HAEi International Patient Organization announce partnership with Inceptua Medicines Access for “HAEi Global Access Program”
7.1.13 Sep 06, 2017: GE Healthcare: Untangling the wires using MRI research to help understand the brain
7.1.14 Aug 02, 2017: Stryker announces election of new Director, Mary K. Brainerd
7.1.15 Jul 24, 2017: Micron Solutions Appoints Rodd E. Friedman to its Board of Directors
7.1.16 Jul 11, 2017: Zimmer Biomet Announces Leadership Transition
7.1.17 Jul 11, 2017: ConforMIS Names Dan Krupp Senior Vice President U.S. Sales
7.2 Financial Announcements
7.2.1 May 15, 2018: Micron Solutions Reports 2018 First Quarter Results
7.2.2 May 02, 2018: Conformis Reports First Quarter 2018 Financial Results
7.2.3 Apr 30, 2018: Orthofix Announces First Quarter 2018 Financial Results
7.2.4 Apr 26, 2018: Zimmer Biomet Reports First Quarter 2018 Financial Results
7.2.5 Apr 26, 2018: Stryker reports first quarter 2018 operating results
7.2.6 Mar 26, 2018: Micron Solutions Reports 2017 Fourth Quarter and Year End Results
7.2.7 Feb 26, 2018: Orthofix International Reports Fourth Quarter And Fiscal 2017 Financial Results
7.2.8 Feb 22, 2018: Can Fite Announces the Submission of Safety Reports for Namodenoson to FDA and other Regulatory Authorities
7.2.9 Feb 07, 2018: ConforMIS Reports Fourth Quarter and the Year Ended 2017 Financial Results; Reiterates 2018 Financial Guidance
7.2.10 Jan 30, 2018: Zimmer Biomet Announces Fourth Quarter and Full-Year 2017 Results
7.2.11 Jan 30, 2018: Stryker reports 2017 results and 2018 outlook
7.2.12 Jan 09, 2018: Stryker provides 2017 preliminary net sales results
7.2.13 Jan 09, 2018: Orthofix Announces Preliminary 2017 Fourth Quarter and Full Year Net Sales Results
7.2.14 Jan 08, 2018: ConforMIS Reports Preliminary Fourth Quarter and Year-End 2017 Revenue Results; Provides 2018 Financial Guidance
7.2.15 Nov 13, 2017: Micron Solutions Reports 2017 Third Quarter Results
7.2.16 Nov 01, 2017: ConforMIS Reports Third Quarter 2017 Financial Results
7.2.17 Nov 01, 2017: Zimmer Biomet Reports Third Quarter 2017 Financial Results
7.2.18 Oct 30, 2017: Orthofix International Reports Third Quarter 2017 Financial Results
7.2.19 Oct 30, 2017: Exactech Q3 Revenue $61.4 Million
7.2.20 Oct 26, 2017: Stryker reports third quarter 2017 results
7.2.21 Oct 06, 2017: Bruker Introduces Fungiplex Candida Assay into European Clinical Microbiology Markets
7.2.22 Oct 06, 2017: Integra LifeSciences launches Revize Collagen Matrix for Plastic and Reconstructive Surgery
7.2.23 Sep 26, 2017: Psychemedics Announces Addition of FDA-Cleared Benzodiazepines Hair Test
7.2.24 Sep 26, 2017: Moleculin Announces FDA Approval of Annamycin IND
7.2.25 Sep 22, 2017: Amedica Releases First and Second Quarter 2017 Preliminary Unaudited Earnings Report and Business Update
7.2.26 Sep 07, 2017: MannKind Responds to Hurricane Harvey Devastation with Afrezza Donation
7.2.27 Aug 11, 2017: Micron Solutions Reports 2017 Second Quarter Results
7.2.28 Aug 07, 2017: Orthofix International Reports Second Quarter 2017 Financial Results
7.2.29 Aug 03, 2017: ConforMIS Reports Second Quarter 2017 Financial Results and Updates Fiscal Year 2017 Guidance
7.2.30 Jul 27, 2017: Zimmer Biomet Reports Second Quarter 2017 Financial Results
7.2.31 Jul 27, 2017: Stryker reports second quarter 2017 results
7.2.32 Jul 27, 2017: Exactech Q2 Revenue $67.3 Million On Continuing Strong Extremities Revenue
7.2.33 Jul 11, 2017: Zimmer Biomet Reports Certain Preliminary Second Quarter 2017 Results
7.2.34 Jun 20, 2017: IsoRay Announces Study Published in The International Journal of Radiation Oncology, Biology, Physics entitled, Clinical Outcomes of Large Brain Metastases Treated with Neurosurgical Resection and Intraoperative Cesium-131 Brachytherapy: Results of
7.2.35 Jun 08, 2017: Amedica Releases 2016 Preliminary Earnings Report and Business Update
7.3 Government and Public Interest
7.3.1 Mar 09, 2018: HSS Study Finds Consensus Needed for Joint Replacement Performance Measurement
7.3.2 Mar 06, 2018: Stem cell centers on the rise, claim high efficacy for treatment of knee osteoarthritis despite lack of evidence
7.3.3 Mar 01, 2018: Multimodal Therapy Reduces the Use of Opioids After Surgery
7.3.4 Aug 29, 2017: ivWatch Awarded New Innovative Technology Contract From Vizient
7.3.5 Jul 11, 2017: Prosthetic knee type may determine cost of care for amputees
7.4 Legal And Regulatory
7.4.1 May 16, 2018: Zimmer Biomet Statement on Warsaw North Campus FDA Inspection
7.4.2 Apr 12, 2018: Sonova Showcases Expanded Product Portfolio at AAA 2018
7.4.3 Feb 22, 2018: GTx Phase 2 Enobosarm Clinical Trial Results in Stress Urinary Incontinence Accepted for Podium Presentation at SUFU
7.4.4 Dec 01, 2017: Amedica Receives Positive Nasdaq Listing Decision
7.4.5 Aug 30, 2017: Medovex Corporation to Present at the 19th Annual Rodman & Renshaw Global Investment Conference
7.4.6 Aug 09, 2017: Novadaq Receives Court Approval for Arrangement With Stryker
7.4.7 Jun 14, 2017: Glenmark Pharmaceuticals receives tentative ANDA approval for Saxagliptin Tablets, 2.5 mg and 5 mg
7.4.8 Jun 13, 2017: Zimmer Biomet Holdings Announces Resolution of FDA Warning Letter Related to Its Zhejiang, China Manufacturing Facility
7.5 Other Significant Developments
7.5.1 May 08, 2018: Amedica Provides Update on its Clinical Studies
7.5.2 Apr 26, 2018: Episurf Medical enters into distribution agreement in Hong Kong and establishes subsidiary in the US
7.5.3 Dec 06, 2017: Advanced, Minimally Invasive Hip and Knee Replacement Procedures Offered at Wilcox Medical Center
7.5.4 Nov 21, 2017: Littleton Adventist to offer robotic technology for knee replacements
7.5.5 Nov 02, 2017: ZS-9 (sodium zirconium cyclosilicate) Phase III long-term safety and efficacy data presented at ASN Kidney Week 2017
7.5.6 Oct 04, 2017: Zimmer Biomet Provides Update on Manufacturing Facilities in Guaynabo and Ponce, Puerto Rico
7.6 Product News
7.6.1 Mar 06, 2018: Exactech Knee System, Ankle, Shoulder Stem, Hip Stem and Computer-Assisted Surgery Technology Headline at Booth 5023, AAOS 2018 Annual Meeting
7.6.2 Mar 06, 2018: Neurocognitive Impairment Linked to Worse Outcomes After Total Joint Replacement
7.6.3 Oct 19, 2017: MicroPort Orthopedics Announces Industry Symposium at American Association of Hip and Knee Surgeons
7.6.4 Oct 16, 2017: Leader of Johnson & Johnson 3D Printing Center of Excellence Outlines Advantages of Customized Knee Implants
7.6.5 Sep 25, 2017: Bone Marrow Concentrate Improves Joint Transplants
7.6.6 Aug 11, 2017: Bonovo participated in the Chinese Medical Association of neurosurgery branch of the 16th academic conference
7.6.7 Aug 05, 2017: Bonovo participated in the first session of the Great Wall Orthopedic Forum, the 14th Beijing Orthopedic Association (BOA) and the first Beijing - Shanghai Orthopedic Summit meeting
7.6.8 Jun 29, 2017: Exactech Introduces New Computer-Assisted Software Application for Simplified Guidance in Total Knee Replacement
7.6.9 Jun 22, 2017: Exactech Expands Presence in Japan with Newly Approved Shoulder, Knee and Hip Replacement Systems
7.7 Strategy And Business Planning
7.7.1 Dec 11, 2017: Anthera Pharmaceuticals Announces Positive Outcome of Interim Futility Analysis in the Phase 3 RESULT Clinical Study of Sollpura
7.7.2 Nov 09, 2017: Arthrex Announces Plans for Expansion of Global Headquarters
7.7.3 Oct 16, 2017: Arthrex Announces Plans for New Surgical Device Manufacturing Facility
8 Appendix
8.1 Research Methodology
8.1.1 Coverage
8.1.2 Secondary Research
8.1.3 Primary Research
8.1.4 Market Modeling and Forecasting
8.1.5 Company Share Analysis
8.1.6 Distribution Share Analysis
8.1.7 Benchmarking
8.2 Consulting
8.3 Contact
8.4 Disclaimer
List of Tables
Table 1: Knee Reconstruction Market, United States, Revenue ($m), USD Constant, 2015-2020
Table 2: Knee Reconstruction Market, United States, Revenue ($m), USD Constant, 2021-2025
Table 3: Partial Knee Replacement Market, United States, Revenue ($m), USD Constant, 2015-2020
Table 4: Partial Knee Replacement Market, United States, Revenue ($m), USD Constant, 2021-2025
Table 5: Primary Knee Replacement Market, United States, Revenue ($m), USD Constant, 2015-2020
Table 6: Primary Knee Replacement Market, United States, Revenue ($m), USD Constant, 2021-2025
Table 7: Knee Reconstruction Market, United States, Volume (Units), 2015-2020
Table 8: Knee Reconstruction Market, United States, Volume (Units), 2021-2025
Table 9: Partial Knee Replacement Market, United States, Volume (Units), 2015-2020
Table 10: Partial Knee Replacement Market, United States, Volume (Units), 2021-2025
Table 11: Primary Knee Replacement Market, United States, Volume (Units), 2015-2020
Table 12: Primary Knee Replacement Market, United States, Volume (Units), 2021-2025
Table 13: Knee Reconstruction Market, United States, Average Price ($), 2015-2020
Table 14: Knee Reconstruction Market, United States, Average Price ($), 2021-2025
Table 15: Knee Reconstruction Market, United States, Distribution Share by Revenue ($m), USD Constant, 2017
Table 16: Knee Reconstruction Market, United States, Company Share by Revenue ($m), USD Constant, 2017
Table 17: Knee Reconstruction Market Pipeline Products
Table 18: Amedica Files Registration Statement for Rights Offering of Units for up to USD11.4 Million
Table 19: ConforMIS Prices USD20 Million in Public Offering of Shares
Table 20: TPG Capital Amends Agreement to Acquire Exactech
Table 21: JANA Partners Denies Rumor to Acquire Certain Stake in Zimmer Biomet
Table 22: Active Implants Raises USD3.3 Million in Venture Financing
Table 23: Total Number of Primary Research Participants, Orthopedic Devices Market, by Country
List of Figures
Figure 1: Knee Reconstruction Market, United States, Revenue ($m), USD Constant, 2015-2025
Figure 2: Partial Knee Replacement Market, United States, Revenue ($m), USD Constant, 2015-2025
Figure 3: Primary Knee Replacement Market, United States, Revenue ($m), USD Constant, 2015-2025
Figure 4: Knee Reconstruction Market, United States, Volume (Units), 2015-2025
Figure 5: Partial Knee Replacement Market, United States, Volume (Units), 2015-2025
Figure 6: Primary Knee Replacement Market, United States, Volume (Units), 2015-2025
Figure 7: Knee Reconstruction Market, United States, Company Share (%) 2017