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Cell-Based Assays: Technologies and Global Markets

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    Report

  • 139 Pages
  • February 2025
  • Region: Global
  • BCC Research
  • ID: 4667529
The Cell-Based Assays Market was valued at USD 35.3 Billion in 2024, and is projected to reach USD 56.3 Billion by 2029, rising at a CAGR of 9.80%. The market’s growth is propelled by multiple factors that contribute to its expansion across many sectors, particularly in drug discovery, toxicity testing, and basic research. Cell-based assays, which utilize live cells to evaluate biological activity, are revolutionizing the life sciences industry by offering more accurate and physiologically relevant models compared to traditional methods such as animal testing. As these assays continue to evolve, they are helping to accelerate drug development processes, improving the efficacy and safety profiles of therapeutic candidates while also reducing animal testing and increasing cost efficiency.

A driver of the cell-based assay market is the increasing demand for novel drug discovery techniques. Pharmaceutical and biotech companies are investing in cell-based assays for high-throughput screening (HTS) to identify potential drug candidates, to evaluate drug efficacy, and to assess compound toxicity early in the drug development process. Compared to traditional biochemical assays, cell-based assays provide more predictive, human-relevant data, which is fundamental for the successful development of new therapeutics. As the pharmaceutical industry seeks to reduce the cost and time of bringing drugs to market, cell-based assays are being adopted as a more efficient alternative.

Additionally, the rise in chronic diseases such as cancer, cardiovascular disease (CVD), diabetes, and neurological disorders is driving the need for more effective and targeted therapies. As these diseases continue to affect a large portion of the global population, the demand for cell-based assays in both basic and clinical research has grown. Researchers are using these assays to better understand disease mechanisms at the cellular level, to identify potential biomarkers, and to evaluate drug responses more accurately. This has led to a surge in R&D investment to advance new cell-based assay technologies.

Report Scope

The scope of this report on the global market for cell-based assay technologies encompasses an analysis of the current landscape, including market size, growth trends and segmentation by product type, application and end user. The report breaks down the cell-based assay market into four product categories: instruments, consumables, services, and software. It also segments the market by application, such as drug discovery; absorption, distribution, metabolism, and excretion (ADME)/toxicity testing; and basic research. The end users considered in the report include academic and research institutions, pharmaceutical and biotech companies, and clinical research organizations.

Geographically, the analysis covers North America, Europe, Asia-Pacific, and Rest of the World (RoW). The report also provides profiles of key market players and highlights industry trends, major products, mergers and acquisitions, and other partnerships expected to influence the future of the industry.

The report includes:

  • 23 data tables and 48 additional tables
  • Analyses of the trends in the global market for cell-based assays, with sales data for 2021-2023, estimates for 2024, and projections of compound annual growth rates (CAGRs) through 2029
  • Evaluation of the market's current and future potential
  • Estimates of the market for cell-based assays, revenue forecasts, and corresponding market share analysis by product, type/application, end user and geographic region
  • Assessment of the current market, new developments, spending trends, and revenue prospects for cell-based assays in the pharmaceutical industry
  • Coverage of major issues involved in the R&D of more effective cell-based approaches for drug discovery
  • Information on increasing investments in R&D activities, key technology issues, industry-specific challenges, major types of end users, and COVID-19 implications
  • Discussion of ESG challenges and practices of the industry
  • Assessment of the competitive landscape, including the market shares of leading companies, their product portfolios and financial overviews
  • Information on recent mergers and acquisitions, expansions, collaborations, investments, divestments and product launches
  • Company profiles of major players within the industry, including Thermo Fisher Scientific Inc., Merck KGaA., Danaher Corp., Bio-Rad Laboratories Inc., and Charles River Laboratories.

Table of Contents

Chapter 1 Executive Summary
  • Market Outlook
  • Scope of Report
  • Market Summary
Chapter 2 Market Overview
  • Overview
  • Drug Discovery
  • Importance of Cell-based Assays
  • Cell Signaling Pathways
  • Mechanisms of Drug Action
  • Gene Expression Regulation
  • Cytotoxicity and Viability
  • Disease Modeling
  • Types of Cell-based Assays
  • Cell Viability Assays
  • Cell Proliferation Assays
  • Cytotoxicity Assays
  • Application of Cell-based Assays
  • Drug Discovery and Development
  • Toxicology Studies
  • Cancer Research
  • Infectious Disease Research
  • Immunology and Inflammation
  • Molecular Pathway Analysis
  • Regenerative Medicine and Tissue Engineering
  • Biomarker Discovery and Validation
  • Precision and Personalized Medicine
Chapter 3 Market Dynamics
  • Overview
  • Market Drivers
  • Rising Incidence of Chronic Diseases
  • Rising Demand for Drug Discovery and Development
  • High Demand for Personalized Medicine
  • Increasing Investment in Drug R&D
  • Market Restraints
  • High Cost of Assay Development and Maintenance
  • Technical Challenges and Complexity
  • Short Shelf-life of Reagents and Consumables
  • Market Opportunities
  • Expanding Applications in Drug Discovery
  • Expansion in Diagnostics and Biomarker Discovery
Chapter 4 Emerging Technologies and Developments
  • Overview
  • Emerging Technologies
  • CRISPR/Cas9 Technology
  • High-content Screening (HCS) and Imaging
  • AI and Machine Learning (ML) in Data Analysis
  • Patent Analysis
  • Patent Review, by Leading Jurisdiction
Chapter 5 Market Segmentation Analysis
  • Overview
  • Segmentation Breakdown
  • Cell-based Assays: Global Markets
  • Market Analysis by Product Type
  • Consumables
  • Instruments
  • Software
  • Services
  • Market Analysis by Application
  • Drug Discovery
  • Absorption, Distribution, Metabolism, and Excretion (ADME)/Toxicity
  • Basic Research
  • Market Analysis by End User
  • Biotechnology and Pharmaceutical Companies
  • Academic and Research Institutes
  • Contract Research Organizations
  • Geographic Breakdown
  • Market Analysis by Region
  • North America
  • Europe
  • Asia-Pacific
  • Rest of the World
Chapter 6 Competitive Intelligence
  • Competitive Landscape
  • Ranking of Companies in the Cell-based Assay Market
Chapter 7 Sustainability in Cell-based Assay Market: An ESG Perspective
  • Sustainability in the Cell-based Assay Market
  • Animal Testing
  • Miniaturization and Automation
  • Green Chemistry and Eco-friendly Materials
  • 3D Cell Cultures and Tissue Models
  • Waste Reduction and Optimization of Resources
  • Improving Drug Discovery Efficiency
  • ESG Risks and Ratings: Understanding the Data
  • BCC Research Viewpoint
Chapter 8 Appendix
  • Methodology
  • Sources
  • Abbreviations
  • Company Profiles
  • AGILENT TECHNOLOGIES INC.
  • BD
  • BIOIVT
  • BIO-RAD LABORATORIES INC.
  • CELL BIOLABS INC.
  • CELL BIOLOGICS INC.
  • CHARLES RIVER LABORATORIES
  • DANAHER CORP.
  • FUJIFILM HOLDINGS CORP.
  • GE HEALTHCARE
  • LONZA
  • MERCK KGAA
  • PROMEGA CORP.
  • REVVITY
  • THERMO FISHER SCIENTIFIC INC.
List of Tables
Summary Table A: Global Market for Cell-based Assays, by Product Type, Through 2029
Summary Table B: Global Market for Cell-based Assays, by Region, Through 2029
Table 1: Factors in Cell-based Assay Development
Table 2: Types of Cellular Assays
Table 3: New Cases and Deaths Due to Selected Cancers Globally, 2022
Table 4: U.S. NIH Funding for Selected Diseases, 2019-2023
Table 5: Existing Cell-based Assay Technologies
Table 6: Patents Issued for Cell-based Assays, by Jurisdiction, 2022-2024
Table 7: Global Market for Cell-based Assays, Through 2029
Table 8: Global Market for Cell-based Assays, by Product Type, Through 2029
Table 9: Global Market for Cell-based Assays, by Application, Through 2029
Table 10: Global Market for Cell-based Assays, by End User, Through 2029
Table 11: Global Market for Cell-based Assays, by Region, Through 2029
Table 12: North American Market for Cell-based Assays, by Country, Through 2029
Table 13: European Market for Cell-based Assays, by Country, Through 2029
Table 14: Asia-Pacific Market for Cell-based Assays, by Country, Through 2029
Table 15: RoW Market for Cell-based Assays, by Subregion, Through 2029
Table 16: Ranking of Companies in Cell-based Assay Market, 2023
Table 17: ESG Rankings for Major Cell-based Assay Companies, 2024*
Table 18: Information Sources in This Report
Table 19: Abbreviations Used in this Report
Table 20: Agilent Technologies Inc.: Company Snapshot
Table 21: Agilent Technologies Inc.: Financial Performance, FY 2022 and 2023
Table 22: Agilent Technologies Inc.: Product Portfolio
Table 23: Agilent Technologies Inc.: News/Key Developments, 2024
Table 24: BD: Company Snapshot
Table 25: BD: Financial Performance, FY 2023 and 2024
Table 26: BD: Product Portfolio
Table 27: BD: News/Key Developments, 2024
Table 28: BioIVT: Company Snapshot
Table 29: BioIVT: Product Portfolio
Table 30: BioIVT: News/Key Developments, 2023 and 2024
Table 31: Bio-Rad Laboratories Inc.: Company Snapshot
Table 32: Bio-Rad Laboratories Inc.: Financial Performance, FY 2022 and 2023
Table 33: Bio-Rad Laboratories Inc.: Product Portfolio
Table 34: Bio-Rad Laboratories Inc.: News/Key Developments, 2021-2024
Table 35: Cell Biolabs Inc.: Company Snapshot
Table 36: Cell Biolabs Inc.: Product Portfolio
Table 37: Cell Biologics Inc.: Company Snapshot
Table 38: Cell Biologics Inc.: Product Portfolio
Table 39: Charles River Laboratories: Company Snapshot
Table 40: Charles River Laboratories: Financial Performance, FY 2022 and 2023
Table 41: Charles River Laboratories: Product Portfolio
Table 42: Charles River Laboratories: News/Key Developments, 2023 and 2024
Table 43: Danaher Corp.: Company Snapshot
Table 44: Danaher Corp.: Financial Performance, FY 2022 and 2023
Table 45: Danaher Corp.: Product Portfolio
Table 46: Fujifilm Holdings Corp.: Company Snapshot
Table 47: Fujifilm Holdings Corp.: Financial Performance, FY 2022 and 2023
Table 48: Fujifilm Holdings Corp.: Product Portfolio
Table 49: GE Healthcare: Company Snapshot
Table 50: GE Healthcare: Financial Performance, FY 2022 and 2023
Table 51: GE Healthcare: Product Portfolio
Table 52: Lonza: Company Snapshot
Table 53: Lonza: Financial Performance, FY 2022 and 2023
Table 54: Lonza: Product Portfolio
Table 55: Lonza: News/Key Developments, 2021
Table 56: Merck KGaA: Company Snapshot
Table 57: Merck KGaA: Financial Performance, FY 2022 and 2023
Table 58: Merck KGaA: Product Portfolio
Table 59: Promega Corp.: Company Snapshot
Table 60: Promega Corp.: Product Portfolio
Table 61: Promega Corp.: News/Key Developments, 2023
Table 62: Revvity: Company Snapshot
Table 63: Revvity: Financial Performance, FY 2022 and 2023
Table 64: Revvity: Product Portfolio
Table 65: Revvity: News/Key Developments, 2023 and 2024
Table 66: Thermo Fisher Scientific Inc.: Company Snapshot
Table 67: Thermo Fisher Scientific Inc.: Financial Performance, FY 2022 and 2023
Table 68: Thermo Fisher Scientific Inc.: Product Portfolio
Table 69: Thermo Fisher Scientific Inc.: News/Key Developments, 2023 and 2024
List of Figures
Summary Figure A: Global Market for Cell-based Assays, by Product Type, 2021-2029
Summary Figure B: Global Market for Cell-based Assays, by Region, 2021-2029
Figure 1: Projected Global Aging Population (65 Years and Above), 1990-2050
Figure 2: Drug Discovery Process Steps
Figure 3: Market Dynamics of Cell-based Assays
Figure 4: FDA Approval of Personalized Medicines, 2015-2022
Figure 5: Pharmaceutical R&D Spending, by Country/Region, 2010-2022
Figure 6: Shares of Global Market for Cell-based Assays, by Product Type, 2023
Figure 7: Shares of Global Market for Cell-based Assays, by Application, 2023
Figure 8: Shares of Global Market for Cell-based Assays, by End User, 2023
Figure 9: R&D Spending of Biopharmaceutical Companies, 2010-2024
Figure 10: Shares of Global Market for Cell-based Assays, by Region, 2023
Figure 11: Shares of North American Market for Cell-based Assays, by Country, 2023
Figure 12: Shares of European Market for Cell-based Assays, by Country, 2023
Figure 13: Shares of Asia-Pacific Market for Cell-based Assays, by Country, 2023
Figure 14: Shares of RoW Market for Cell-based Assays, by Subregion, 2023
Figure 15: Agilent Technologies Inc.: Revenue Share, by Business Unit, FY 2023
Figure 16: Agilent Technologies Inc.: Revenue Share, by Country/Region, FY 2023
Figure 17: BD: Revenue Share, by Business Unit, FY 2024
Figure 18: BD: Revenue Share, by Country/Region, FY 2024
Figure 19: Bio-Rad Laboratories Inc.: Revenue Share, by Business Unit, FY 2023
Figure 20: Bio-Rad Laboratories Inc.: Revenue Share, by Country/Region, FY 2023
Figure 21: Charles River Laboratories: Revenue Share, by Business Unit, FY 2023
Figure 22: Charles River Laboratories: Revenue Share, by Country/Region, FY 2023
Figure 23: Danaher Corp.: Revenue Share, by Business Unit, FY 2023
Figure 24: Danaher Corp.: Revenue Share, by Country/Region, FY 2023
Figure 25: Fujifilm Holdings Corp.: Revenue Share, by Business Unit, FY 2023
Figure 26: Fujifilm Holdings Corp.: Revenue Share, by Country/Region, FY 2023
Figure 27: GE Healthcare: Revenue Share, by Business Unit, FY 2023
Figure 28: GE Healthcare: Revenue Share, by Country/Region, FY 2023
Figure 29: Lonza: Revenue Share, by Business Unit, FY 2023
Figure 30: Merck KGaA: Revenue Share, by Business Unit, FY 2023
Figure 31: Merck KGaA: Revenue Share, by Country/Region, FY 2023
Figure 32: Revvity: Revenue Share, by Business Unit, FY 2023
Figure 33: Revvity: Revenue Share, by Country/Region, FY 2023
Figure 34: Thermo Fisher Scientific Inc.: Revenue Share, by Business Unit, 2023
Figure 35: Thermo Fisher Scientific Inc.: Revenue Share, by Country/Region, 2023

Executive Summary

Cell-based assays are basically experiments used to study, analyze and understand how live cells respond to external factors. These assays are commonly used in drug discovery for validating drug targets. They are also used in lead profiling, in basic research for understanding cell signaling and function, and for ADME toxicity testing.

It has been observed that pharmaceutical R&D expenses place a significant burden on the healthcare industry because the drug discovery and development entails substantial time and resources to recognize an effective drug that can progress to clinical trial. This long process has a success rate of around 10%-12%, that is only 10% of the drugs get approval after undergoing clinical trials. So, using cell-based assays will be helpful in the initial step of drug discovery as it will help to screen the compounds. Also, with the advancement of technologies, automated processes are being used for drug screening and development purposes. Studies have indicated that using methods such as cell-based assays earlier in the drug development cycle will help in eliminating the toxic products and avoid late - stage drug failures and financial losses. Since live cells are used in cell-based assays, they are biologically more relevant and will also help in replacing animal testing.

There is a need to grow product pipelines for companies. The benefits of cell-based assays over in vivo methods have led to their increased use in drug discovery. In vitro cell-based methods also offer flexibility and cost advantages. In addition, advancements in automation and high-throughput techniques are offering support to this market.

The increasing prevalence of chronic diseases, aging population and increased healthcare expenditure are driving the drug discovery market. There are many diseases that still do not have any approved therapies for cures and depend only on symptomatic management, e.g., amyotrophic lateral sclerosis, cirrhosis, non-alcoholic steatohepatitis, etc. Therefore, cell-based assays will be beneficial for such indications. More research and the increasing prevalence of cancer as well as neurogenerative diseases, such as Alzheimer’s, Parkinson’s disease and other rare indications, will also be contributing factors for the market.

Personalized drug treatment is becoming a reality. In response to the rise in the incidence of a number of diseases and an aging population, the drug discovery industry is developing new and more efficacious drugs based on specific biomarker signatures. These drugs can be developed and tested to meet specific endpoints with the use of cell-based assays.

Companies Mentioned

  • Agilent Technologies Inc.
  • BD
  • Bioivt
  • Bio-Rad Laboratories Inc.
  • Cell Biolabs Inc.
  • Cell Biologics Inc.
  • Charles River Laboratories
  • Danaher Corp.
  • Fujifilm Holdings Corp.
  • GE Healthcare
  • Lonza
  • Merck KGaA
  • Promega Corp.
  • Revvity
  • Thermo Fisher Scientific Inc.

Table Information