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Developing Bioinformatics Infrastructures

  • Book

  • May 2019
  • Elsevier Science and Technology
  • ID: 4700314
Bioinformatics software, information-rich life sciences databases, and high throughput laboratory technologies provide life and biosciences professionals with access to data and analytical tools that drive discovery at a rate previously unprecedented in science. This book shows bioinformatics professionals how to maximize the power of these systems for interoperability and integration. It provides the methodologies and tools required to develop infrastructures that support collaborative research in both academic and commercial research laboratories.

The reader is walked through the development of a web services-based infrastructure that will provide secure information management and discovery systems to facilitate information exchange and analysis.

Table of Contents

Introduction; Systems Biology: The New Research Paradigm, and the Enabling Role of Bioinformatics; Fundamental Technologies for Bioinformatics; Elements of Bioinformatics Infrastructures; Data Storage Design with Data Integration, Data Exchange, and Process Interoperability in Mind; Laboratory Information Management Systems (LIMS); Data Pipelines; Discovery Systems; Tying it all Together; Future Directions

Authors

Theodore S. Kalbfleisch Center for Genetics and Molecular Medicine University of Louisville Louisville, KY.

2005-Present, Associate Director of Bioinformatics, Center for Genetic and Molecular Medicine, University of Louisville, Louisville, KY

1999-2004 Associate Director of Process Software Development, Genaissance Pharmaceuticals, New Haven, CT

1996-1999 Group Leader, Bioinformatics Department, CuraGen Corp., New Haven, CT

1994-1996 Post Doctoral Fellowship, Boston University, Boston, MA

1994 Ph.D Physical Chemistry, Boston University, Boston, MA

1988 B.S University of Louisville, Louisville, KY