- Emphasizes clinical aspects of immunology, including disease pathogenesis, the development of novel therapies based on basic science, and an appendix of clinical cases for real-world application. - Provides top-notch instruction from experienced teachers, course directors, and lecturers led by well-known editor and author Dr. Abul Abbas. - Features a highly readable writing style and practical organization, now with fully revised content and updated images to reflect recent important advances in today's understanding of the immune system. - Provides additional online features such as answers to in-book chapter review questions, helpful animations, and up to 10 self-assessment questions per chapter. - Presents information in a format and style that maximizes usefulness to students and teachers studying medicine, allied health fields, and biology. - Contains numerous features designed to help students understand key immunologic concepts: high-quality illustrations, practical tables, chapter outlines, bolded key points, and focus questions in every chapter for self-assessment and review. - Includes an Enhanced eBook version with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Table of Contents
1 Introduction to the Immune System Nomenclature, General Properties, and Components 2 Innate Immunity The Early Defense Against Infections 3 Antigen Capture and Presentation to Lymphocytes What Lymphocytes See 4 Antigen Recognition in the Adaptive Immune System Structure of Lymphocyte Antigen Receptors and Development of Immune Repertoires 5 T Cell-Mediated Immunity Activation of T Lymphocytes 6 Effector Mechanisms of T Cell-Mediated Immunity Functions of T Cells in Host Defense 7 Humoral Immune Responses Activation of B Lymphocytes and Production of Antibodies 8 Effector Mechanisms of Humoral Immunity Elimination of Extracellular Microbes and Toxins 9 Immunological Tolerance and Autoimmunity Self-Nonself Discrimination in the Immune System and Its Failure 10 Immune Responses Against Tumors and Transplants Immunity to Noninfectious Transformed and Foreign Cells 11 Hypersensitivity Disorders Caused by Immune Responses 12 Congenital and Acquired Immunodeficiencies Diseases Caused by Defective Immunity Selected Readings Appendix I Glossary Appendix II Cytokines Appendix III Principal Features of Selected CD Molecules APPENDIX IV Clinical Cases
