Cellular Signalling in Cancer Metastasis

Cellular Signalling in Cancer Metastasis provides the reader with in-depth information on the cellular signalling mechanisms responsible for cancer metastasis. Cancer metastasis is the major cause of cancer-associated mortality. Understanding the cellular signalling mechanisms and molecules involved in cancer metastasis help devise better therapeutic interventions.

Cancer-associated deaths are mainly attributed to the dislodging of cells from the primary site of origin and establishment of colonies at distal secondary sites, termed metastasis. While there has been made significant progress in understanding the mechanisms responsible for metastasis, there is a lack of a comprehensive book compiling these aspects between one cover. This book fills that gap and provides vital information that could be exploited for the development of better therapeutics.

The book is intended to help any entry level researchers from graduation students, postdocs and early career scientists and is detailed enough to be considered by seasoned scientists. It provides the reader with the current knowledge available on the subject and stimulates others to take up investigations on understanding of cancer metastasis, as it is the cause of cancer-associated mortality and morbidity.

• Provides readers with in-depth information on the cellular signaling mechanisms responsible for cancer metastasis
• Explains the signaling pathways associated with metastasis, ranging from clinical management of metastatic disease, to a systems biology approach
• Brings together the current knowledge on signaling pathways and the mechanisms responsible for the induction and progression of metastasis, along with present therapeutic options and challenges