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Laboratory Animal Models, 3D Cultures and Organoids: Global Markets

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    Report

  • 198 Pages
  • August 2022
  • Region: Global
  • BCC Research
  • ID: 4758145

Report Scope

The report describes three global markets: the animal models market, the 3D cultures market and the organoids market. The organoids market especially is described in more detail, with market estimation for different segments in a separate chapter of the report.

Report Includes

  • 26 data tables and 28 additional tables
  • An up-to-date review and analysis of the global markets for the laboratory animal models, 3D cell cultures, and organoids within the industry
  • Analyses of the global market trends, with historic market revenue data for 2019-2021, estimates for 2022, and projections of compound annual growth rates (CAGRs) through 2027
  • Highlights of the current state of the industry structure, novel technological updates and issues surrounding integration of organoids and stringent regulatory constraints, ongoing research activities, and COVID-19 impact on the overall market
  • Estimation of the actual market size and market forecast for organoids in USD million values, and their corresponding market share analysis by product type, application, and geographic region
  • Regional and country specific data and analysis for organoids in the U.S., Canada, Germany, U.K., France, Italy, Spain, Japan, Australia, China and India etc.
  • Information on the current trends that significantly affect the basic research, biomedical and other industries where animals are used for toxicity testing and also for evaluating the safety and metabolism of chemical compounds
  • Analysis of market opportunities with a holistic review of advantages and disadvantages of the 3D cell cultures, animal models, and organoids in the prevailing biopharmaceuticals industry
  • Review of selected patents and patent applications on organoids, and emerging developments in the global market
  • Identification of the major stakeholders and analysis of the competitive landscape based on recent developments and segmental revenues
  • Descriptive company profiles of the leading Organoids market players, including Cellesce Ltd., Corning Inc., Merck KGaA, Thermo Fisher Scientific Inc., Hubrecht Organoid Technology (HUB), and STEMCELL Technologies Inc.

Table of Contents

Chapter 1 Introduction
  • Background
  • Study Goals and Objectives
  • Reasons for Doing this Study
  • Scope of Report
  • What's New in this Update?
  • Information Sources and Methodology
  • Geographic Breakdown
  • Analyst's Credentials
  • Custom Research
  • Related Research Reports
Chapter 2 Summary and Highlights
Chapter 3 Animal Model Market Technology Background
  • Methods of Animal Model and 3D Cell Culture Modification
  • Physical and Chemical Mutations
  • Targeted Mutations
  • Other Technologies
  • Laboratory Animal Models
  • Market Definition
  • Animal Model Lines
  • Common Species of Laboratory Animals
Chapter 4 Impact of Covid-19 on the Global Market for Organoids
  • Overview
  • Impact of Covid-19 on Organoids
  • Conclusion
Chapter 5 Market Dynamics
  • Market Drivers
  • Increasing Emphasis on Developing Alternative Approaches to Animal Testing
  • Rising Demand for Tumor Modelling and Biobanking to Drive Market Growth
  • Increasing Adoption of the Organoid Technology for Wide Range of Applications
  • Market Restraints
  • Stringent Government Regulatory Setting in Research and Development of Cell Cultures and Stem Cells
  • Concerns Associated With the Integration of Organoids into Current Workflows
  • Market Opportunities
  • Increasing Applications of Organoids in Drug Development, Personalized Medicine and Transplantational Medicine
Chapter 6 3D Cell Technology Background
  • 3D Cell Cultures
  • Spheroids
  • 2D Cultures Vs. 2.5D Cultures Vs. 3D Cultures
  • Scaffold-Based and Scaffold-Free 3D Cell Cultures
  • Scaffold-Free 3D Cell Cultures
  • Scaffold-Based 3D Cell Cultures
  • Tissue Engineering and Bioprinting
  • 3D Bioprinting Technology
  • Types of Bioprinting Methods
  • Microfluidic Organ-On-Chip Platforms
  • Types of Organ-On-Chip Devices
Chapter 7 Market Breakdown by Organ Type
  • Global Market for Organoids, by Organ Type
  • Intestine
  • Market Size and Forecast
  • Liver
  • Market Size and Forecast
  • Stomach
  • Market Size and Forecast
  • Pancreas
  • Market Size and Forecast
  • Lung (Pulmonary)
  • Market Size and Forecast
  • Kidney
  • Market Size and Forecast
  • Others
  • Cardiac Organoids
  • Cancer Organoids
  • Market Size and Forecast
Chapter 8 Market Breakdown by Application
  • Global Market for Organoids, by Application
  • Developmental Biology
  • Market Size and Forecast
  • Drug Discovery and Personalized Medicine
  • Market Size and Forecast
  • Regenerative Medicine
  • Market Size and Forecast
  • Pathology of Infectious Disease
  • Market Size and Forecast
  • Drug Toxicity and Efficacy Testing
  • Market Size and Forecast
Chapter 9 Market Breakdown by Region
  • Global Market for Organoids, by Region
  • North America
  • U.S.
  • Canada
  • Europe
  • Germany
  • France
  • U.K.
  • Italy
  • Spain
  • Rest of Europe
  • Asia-Pacific
  • China
  • Japan
  • Australia
  • India
  • Rest of Asia-Pacific
  • Rest of the World
  • Market Size and Forecast
Chapter 10 Patent Review/New Developments
Chapter 11 Analysis of Market Opportunities
  • Market Opportunities: Animal Models
  • Market Opportunities: 3D Cell Culture Segment
  • Organs-On-Chip
  • Organoids
  • Bioprinting
  • Advantages and Disadvantages of 3D Cell Cultures and Animal Models
  • Animal Models
  • 3D Cell Cultures in General
  • Organoids
  • Organs-On-Chip
Chapter 12 Competitive Landscape
Chapter 13 Profiles of Companies and Important Institutions
  • Animal Model Companies
  • Alpha Genesis Inc.
  • Charles River Laboratories International Inc.
  • Envigo
  • Genoway S.A.
  • Labcorp Drug Development (Covance Inc.)
  • The Jackson Laboratory
  • Janvier Labs
  • Oak Hill Genetics
  • Primgen
  • Taconic Biosciences
  • Transgenic Inc.
  • Transposagen Biopharmaceuticals Inc.
  • Bioprinting and Regenerative Medicine Companies
  • Allevi
  • Aspect Biosystems Ltd.
  • Bioink Solutions Inc.
  • Cellink Inc.
  • Collplant Holdings Ltd.
  • East River Biosolutions/Xylyx Bio
  • Epibone
  • Mattek Corp.
  • Nano 3D Biosciences Inc.
  • Organovo Holdings Inc.
  • Pepgel LLC
  • Regenhu
  • Tevido Biodevices Inc.
  • Tissuse GmbH
  • Organ-On-Chip Companies
  • Axosim
  • Emulate Inc.
  • Kirkstall Ltd.
  • Micronit Microtechnologies
  • Mimetas
  • Tara Biosystems Inc.
  • Organoid Companies
  • 3Dnamics Inc.
  • Cellesce
  • Cincinnati Children's Hospital Medical Center
  • Crown Bioscience
  • Corning Inc.
  • Definigen
  • Hubrecht Organoid Technology (Hub)
  • Merck Kgaa
  • R&D Systems Inc.
  • Stemcell Technologies Inc.
  • Thermo Fisher Scientific
  • Trevigen Inc. (Bio-Techne)
  • Other 3D Cell Culture Companies
  • 3D Biotek LLC
  • Advanced Biomatrix Inc.
  • Horizon Discovery Ltd.
  • Insphero Inc.
  • Promocell GmbH
  • Reprocell Inc.
  • Synthecon Inc.
List of Tables
Summary Table: Global Market for Organoids, by Organ Type, Through 2027
Table A: Comparison of Changes in the Segmentation of the Old and New Version of the Report
Table 1: Global Market for Organoids, by Organ Type, Through 2027
Table 2: Global Market for Intestine Organoids, by Region, Through 2027
Table 3: Global Market for Liver Organoids, by Region, Through 2027
Table 4: Global Market for Stomach Organoids, by Region, Through 2027
Table 5: Global Market for Pancreatic Organoids, by Region, Through 2027
Table 6: Global Market for Lung Organoids, by Region, Through 2027
Table 7: Global Market for Kidney Organoids, by Region, Through 2027
Table 8: Global Market for Other Organoids Segment, by Region, Through 2027
Table 9: Global Market for Organoids, by Application, Through 2027
Table 10: Global Market for Organoids in Developmental Biology, by Region, Through 2027
Table 11: Global Market for Organoids in Drug Discovery and Personalized Medicine, by Region, Through 2027
Table 12: Global Market for Organoids in Regenerative Medicine, by Region, Through 2027
Table 13: Global Market for Organoids in Pathology of Infectious Disease, by Region, Through 2027
Table 14: Global Market for Organoids in Drug Toxicity and Efficacy Testing, by Region, Through 2027
Table 15: Global Market for Organoids, by Region, Through 2027
Table 16: North American Market for Organoids, by Organ Type, Through 2027
Table 17: North American Market for Organoids, by Country, Through 2027
Table 18: European Market for Organoids, by Organ Type, Through 2027
Table 19: European Market for Organoids, by Country, Through 2027
Table 20: Asia-Pacific Market for Organoids, by Organ Type, Through 2027
Table 21: Asia-Pacific Market for Organoids, by Country, Through 2027
Table 22: Rest of the World Market for Organoids, by Organ Type, Through 2027
Table 23: Review of Selected Patents and Patent Applications on Organoids, 2008-2021
Table 24: Global Number of Transplanted Organs, by Country, 2017
Table 25: Global Organoids Vendors, by Ranking, 2021
Table 26: Alpha Genesis Inc.: Recent Developments, 2017-2020
Table 27: Charles River Laboratories International Inc.: Recent Developments, 2020-2022
Table 28: Envigo: Types of Laboratory Animals
Table 29: Envigo: Recent Developments, 2021-2022
Table 30: GenOway: Recent Developments, 2018-2022
Table 31: LabCorp Drug Development: Recent Developments, 2022
Table 32: The Jackson Laboratory: Recent Developments, 2021
Table 33: Janvier Labs: Segments
Table 34: Taconic Biosciences: Segments
Table 35: Transgenic Inc.: Segments
Table 36: Transgenic Inc.: Company Financials, 2014-2018
Table 37: Transposagen Biopharmaceuticals Inc.: Segments
Table 38: Organovo: Expenses on R&D, 2016-2020
Table 39: Cellesce.: Recent Developments, 2018-2022
Table 40: Cincinnati Children's Hospital Medical Center: Recent Developments, 2021
Table 41: Crown Bioscience: Recent Developments, 2021-2022
Table 42: Corning Inc.: Recent Developments, 2018-2021
Table 43: DefiniGEN: Recent Developments, 2020-2021
Table 44: Hubrecht Organoid Technology (HUB): Recent Developments, 2017-2021
Table 45: Merck KGaA: Products Offered
Table 46: Merck KGaA: Recent Developments, 2020-2021
Table 47: STEMCELL Technologies Inc.: Recent Developments, 2018-2022
Table 48: Thermo Fisher Scientific: Products Offered
Table 49: Thermo Fisher Scientific: Recent Developments
Table 50: 3D Biotek LLC: Segments
Table 51: In Sphero Inc.: Segments
Table 52: Reprocell Inc.: Acquisitions

List of Figures
Summary Figure: Global Market Share for Organoids, by Organ Type, 2021
Figure 1: Timeline for Possible Availability of 3D-Printed Organs and Tissues for Humans, 2018-2043
Figure 2: Timeline for Possible Availability of Organ-on-Chip Devices for Drug Screening in Human Patients, 2018-2030
Figure 3: Global Market Share for Organoids, by Organ Type, 2021
Figure 4: Global Market for Intestine Organoids, 2020-2027
Figure 5: Global Market for Intestine Organoids, by Region, 2020-2027
Figure 6: Global Market for Liver Organoids, 2020-2027
Figure 7: Global Market for Liver Organoids, by Region, 2020-2027
Figure 8: Global Market for Stomach Organoids, 2020-2027
Figure 9: Global Market for Stomach Organoids, by Region, 2020-2027
Figure 10: Global Market for Pancreatic Organoids, 2020-2027
Figure 11: Global Market for Pancreatic Organoids, by Region, 2020-2027
Figure 12: Global Market for Lung Organoids, 2020-2027
Figure 13: Global Market for Lung Organoids, by Region, 2020-2027
Figure 14: Global Market for Kidney Organoids, 2020-2027
Figure 15: Global Market for Kidney Organoids, by Region, 2020-2027
Figure 16: Global Market for Other Organoids Segment, 2020-2027
Figure 17: Global Market for Other Organoids Segment, by Region, 2020-2027
Figure 18: Global Market Share for Organoids, by Application, 2021
Figure 19: Global Market for Organoids in Developmental Biology, 2020-2027
Figure 20: Global Market for Organoids in Developmental Biology, by Region, 2020-2027
Figure 21: Global Market for Organoids in Drug Discovery and Personalized Medicine, 2020-2027
Figure 22: Global Market for Organoids in Drug Discovery and Personalized Medicine, by Region, 2020-2027
Figure 23: Global Market for Organoids in Regenerative Medicine, 2020-2027
Figure 24: Global Market for Organoids in Regenerative Medicine, by Region, 2020-2027
Figure 25: Global Market for Organoids in Pathology of Infectious Disease, 2020-2027
Figure 26: Global Market for Organoids in Pathology of Infectious Disease, by Region, 2020-2027
Figure 27: Global Market for Organoids in Drug Toxicity and Efficacy Testing, 2020-2027
Figure 28: Global Market for Organoids in Drug Toxicity and Efficacy Testing, by Region, 2020-2027
Figure 29: Global Market for Organoids, by Region, 2020-2027
Figure 30: Global Market Share for Organoids, by Region, 2021
Figure 31: North American Market Share for Organoids, by Organ Type, 2021
Figure 32: North American Market Share for Organoids, by Country, 2021
Figure 33: U.S. Market for Organoids, 2020-2027
Figure 34: Canadian Market for Organoids, 2020-2027
Figure 35: European Market Share for Organoids, by Organ Type, 2021
Figure 36: European Market Share for Organoids, by Country, 2021
Figure 37: German Market for Organoids, 2020-2027
Figure 38: French Market for Organoids, 2020-2027
Figure 39: U.K. Market for Organoids, 2020-2027
Figure 40: Italian Market for Organoids, 2020-2027
Figure 41: Spanish Market for Organoids, 2020-2027
Figure 42: Rest of the European Market for Organoids, 2020-2027
Figure 43: Asia-Pacific Market Share for Organoids, by Organ Type, 2021
Figure 44: Asia-Pacific Market Share for Organoids, by Country, 2021
Figure 45: Chinese Market for Organoids, 2020-2027
Figure 46: Japanese Market for Organoids, 2020-2027
Figure 47: Australian Market for Organoids, 2020-2027
Figure 48: Indian Market for Organoids, 2020-2027
Figure 49: Rest of Asia-Pacific Market for Organoids, 2020-2027
Figure 50: Rest of the World Market Share for Organoids, by Organ Type, 2021
Figure 51: Global Number of Transplanted Organs, by Country, 2017
Figure 52: Charles River Laboratories International Inc.: Net Revenue, 2017-2021
Figure 53: Charles River Laboratories International Inc.: Revenue Share, by Business Segment, 2021
Figure 54: Charles River Laboratories International Inc.: Revenue Share, by Region, 2021
Figure 55: GenOway: Net Revenue, 2019-2021
Figure 56: LabCorp Drug Development: Net Revenue, 2017-2021
Figure 57: LabCorp Drug Development: Revenue Share, by Business Segment, 2021
Figure 58: LabCorp Drug Development: Revenue Share, by Region, 2021
Figure 59: The Jackson Laboratory: Net Revenue, 2018-2020
Figure 60: The Jackson Laboratory: Revenue Share, by Business Segment, 2020
Figure 61: Corning Inc.: Net Revenue, 2019-2021
Figure 62: Corning Inc.: Revenue Share, by Business Segment, 2020
Figure 63: Corning Inc.: Revenue Share, by Region, 2020
Figure 64: Merck KGaA: Net Revenue, 2017-2021
Figure 65: Merck KGaA: Revenue Share, by Business Segment, 2020
Figure 66: Merck KGaA: Revenue Share, by Region, 2020
Figure 67: Thermo Fisher Scientific: Net Revenue, 2017-2021
Figure 68: Thermo Fisher Scientific: Revenue Share, by Business Segment, 2020
Figure 69: Thermo Fisher Scientific: Revenue Share, by Region, 2020

Executive Summary

The fast growth rate of the kidney segment is attributed to growing adoption of kidney organoids, which results from their exceptional ability, derived from the use of disease-specific human pluripotent stem cells (hPSCs), to reproduce human diseases caused by genetic alterations. This has helped to usher in the next generation of kidney disease models.

The global organoids market is segmented in this report by technology, application and region.

Companies Mentioned

  • Animal Model Companies
  • Alpha Genesis Inc.
  • Charles River Laboratories International Inc.
  • Envigo
  • Genoway S.A.
  • Labcorp Drug Development (Covance Inc.)
  • The Jackson Laboratory
  • Janvier Labs
  • Oak Hill Genetics
  • Primgen
  • Taconic Biosciences
  • Transgenic Inc.
  • Transposagen Biopharmaceuticals Inc.
  • Bioprinting and Regenerative Medicine Companies
  • Allevi
  • Aspect Biosystems Ltd.
  • Bioink Solutions Inc.
  • Cellink Inc.
  • Collplant Holdings Ltd.
  • East River Biosolutions/Xylyx Bio
  • Epibone
  • Mattek Corp.
  • Nano 3D Biosciences Inc.
  • Organovo Holdings Inc.
  • Pepgel LLC
  • Regenhu
  • Tevido Biodevices Inc.
  • Tissuse GmbH
  • Organ-On-Chip Companies
  • Axosim
  • Emulate Inc.
  • Kirkstall Ltd.
  • Micronit Microtechnologies
  • Mimetas
  • Tara Biosystems Inc.
  • Organoid Companies
  • 3Dnamics Inc.
  • Cellesce
  • Cincinnati Children's Hospital Medical Center
  • Crown Bioscience
  • Corning Inc.
  • Definigen
  • Hubrecht Organoid Technology (Hub)
  • Merck Kgaa
  • R&D Systems Inc.
  • Stemcell Technologies Inc.
  • Thermo Fisher Scientific
  • Trevigen Inc. (Bio-Techne)
  • Other 3D Cell Culture Companies
  • 3D Biotek LLC
  • Advanced Biomatrix Inc.
  • Horizon Discovery Ltd.
  • Insphero Inc.
  • Promocell GmbH
  • Reprocell Inc.
  • Synthecon Inc.

Table Information