Research has clearly established a link between omega fatty acids and general health, particularly cardiovascular health. Omega Fatty Acids in Brain and Neurological Health, Second Edition, illustrates the importance of omega-3 fatty acids in longevity, cognitive impairment and structure and function of the brain's neurons and also the adverse effects of omega-6 fatty acids on neurological function. This book encompasses some of the most recent research on the links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements on hippocampal neurogenesis, substantia nigra modulation, migraine headaches, the developing brain in animals, sleep and neurodegenerative diseases. This completely updated second edition focuses on the counterbalancing dietary and tissue omega-6 fatty acids as well as it studies the effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases.
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Table of Contents
A. Omega Fatty acids and Brain: An overview 1. Essentiality of Omega-3 Polyunsaturated Fatty Acids for Mammalian Brain Development: A Translational Perspective 2. Thinking in polyunsaturated fatty acids, phospholipids and the brain 3. The Impact of Omega-3 Fatty Acids on Quality of Life 4. The Balance Between n-6 and n-3 and its Relation to Executive Function 5. Arachidonic Acid, Docosahexaenoic Acid, and Ethanol
B. Omega fatty acids: Brain and neurological development 6. Prenatal n-3 long-chain polyunsaturated fatty acids and children's executive functions 7. Omega-3 and Omega-6 fatty acid metabolism: Modeling growth and disease using Caenorhabditis elegans 8. Fatty acids and the hippocampus 9. Energy metabolism of neural cells under the control of phospholipases A2 and docosahexaenoic acid 10. Omega-3 and Cognition in Children with Malnutrition 11. Neuroprotective effects of melatonin and omega-3 on the central nervous system exposed to electromagnetic fields in the pre- and postnatal periods 12. Maternal omega 3 status: effects of cross-fostering on offspring brain lipids and hippocampal neurogenesis 13. Linking omega-3 fatty acids and depression 14. Omega 3 Fatty Acids and the Cardiovascular System
C. Diet and Brain disease treatment and Prevention 15. Dietary Strategies and Supplements for the Prevention of Cognitive Decline and Alzheimer's disease 16. N-3 long chain PUFA-containing phospholipids and neuroprotection 17. Omega-3 Polyunsaturated Fatty Acid Supplementation as a Potential Protective Factor or Treatment for Neurodegenerative Diseases 18. Neurobiological meaning of Omega-3 Fatty Acids and their potential role in the treatment of schizophrenia 19. Neurodevelopmental and behavioral effects of variations in Omega-3 Polyunsaturated Fatty Acids levels in vulnerable populations
D. Nutrients and the Brain 20. Omega-3 fatty acids and cognitive behavior 21. Link between sugar intake and fatty acid metabolism in brain 22. N-3 and -6 fatty acids in fish: a focus on non-marine species 23. Aspartame Induced Neurodegeneration Versus Omega 3 Alleviation 24. DHA-enriched formulations as a promising strategy for the treatment of hypoxic/ischemic brain injury 25. Alpha-linolenic acid and dementia in epidemiological studies 26. DHA a Key Supplement For Neurologic Health- An Insight 27. Obesity, Cognitive Functioning, and Dementia: A Lifespan Perspective 28. Fatty acids and brain health 29. Epigenetic effects of omega-3 fatty acids on neurons and astrocytes during brain development and senescence
Authors
Ronald Ross Watson Professor, Mel and Enid Zuckerman College of Public Health and School of Medicine, Arizona Health Sciences Center, University of Arizona, Tucson, AZ, USA. Ronald Ross Watson, PhD, is Professor of Health Promotion Sciences at the University of Arizona, Mel and Enid Zuckerman College of Public Health. Dr. Watson began his research in public health at the Harvard School of Public Health as a Fellow in 1971 doing field work on vaccines in Saudi Arabia. He has done clinical studies in Colombia, Iran, Egypt, Saudi Arabia and the United States which provides a broad international view of public health. He has served in the military reserve hospital for 17 years with extensive training in medical responses to disasters as the chief biochemistry officer of a general hospital, retiring as a Lt. Colonel. He is a distinguished member of several national and international nutrition, immunology, and cancer societies. Dr. Watson's career has involved studying many lifestyle aspects for their uses in health promotion. He has edited over 100 biomedical reference books and 450 papers and chapters. His teaching and research focuses on alcohol, tobacco, and drugs of abuse in heart function and disease in mouse models. Victor R Preedy Professor in the Department of Clinical Biochemistry at King's College Hospital, London, UKEmeritus Professor in Faculty of Life Sciences and Medicine at King's College London, UK Visiting Professor at the University of Hull, UK. Professor Preedy has been elected as a Fellow to the following Royal Societies: The Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health and Hygiene, the Royal Society for Public Health, the Royal Society of Chemistry, and the Royal Society of Medicine. He was founding Director of the Genomics Centre at King's College London and held the post from 2006 to 2020. He is a leading expert on the science of health and has a long-standing interest in disease processes, biomarkers, and tissue pathology. He has lectured nationally and internationally. Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.
