Clinical and Basic Neurogastroenterology and Motility is a state-of-the-art, lucidly written, generously illustrated, landmark publication that comprehensively addresses the underlying mechanisms and management of common adult and pediatric motility disorders. These problems affect 50% of the population and include conditions such as dysphagia, achalasia, gastroesophageal reflux disease, gastroparesis, irritable bowel syndrome (IBS), gas and bloating, SIBO, constipation and fecal incontinence. The book brings together international experts and clinician scientists, epitomizing their years of wisdom into a concise yet practical text that is delivered in two distinct sections, basic and clinical. It fulfills a large unmet need, and bridges a long-awaited knowledge gap among trainees, clinicians, scientists, nurses and technicians, earnestly engaged in this field.
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Table of Contents
Section 1: Foundations of neurogastroenterology and motility 1. Nerves, smooth muscle cells and interstitial cells in the GI tract: molecular and cellular interactions 2. Gut and brain interactions 3. Neuroimaging and biomarkers in functional gastrointestinal disorders 4. Gut microbiota and immunology of the gastrointestinal tract 5. Esophageal anatomy and physiology 6. Gastroduodenal anatomy and physiology 7. Small intestine anatomy and physiology 8. Colon and pelvic floor anatomy and physiology 9. Investigation of the brain and gut axis 10. Neurogastroenterology and motility laboratory: The nuts and bolts
Section 2: Diagnostic tests and clinical approaches to neurogastroentereology and motility disorders Esophagus 11. Deglutition and oropharyngeal dysphagia 12. Functional dysphagia and globus 13. Esophageal body motility disorders 14. Achalasia 15. Gastroesophageal reflux disorders 16. Barrett's, esophageal sensation and reflux 17. Functional heartburn, functional chest pain and reflux hypersensitivity Stomach 18. Gastroparesis and other gastric motility disorders 19. Functional dyspepsia 20. Nausea, belching and rumination disorders 21. Investigation of small bowel motility Small Bowel 22. Investigations of dietary malabsorption and gut microbiota 23. Biliary motility and sphincter of Oddi disorders 24. Small intestinal bacterial overgrowth and small intestinal fungal overgrowth 25. Investigation of diet, nutrition and gut microbiota 26. FODMAPs and carbohydrate intolerance 27. Food allergy and hypersensitivity Colon and Anorectum 28. Investigation of anorectal motility 29. Investigation of colonic motility 30. Irritable bowel syndrome 31. Chronic constipation 32. Dyssynergic defecation and defecatory disorders 33. Opioid-induced bowel disorders and narcotic bowel syndrome 34. Functional diarrhea 35. Fecal incontinence 36. Anorectal pain 37. Biofeedback therapy Pediatric Neurogastroenterology and motility disorders 38. Neurogastroenterology and motility disorders in pediatric populations 39. Functional gastrointestinal disorders in paediatric populations
Section 3: Biopsychosocial and systemic neurogastroenterology and motility 40. Multicultural factors in the treatment of patients with FGIDs 41. Behavioral and non-pharmacological management of functional gastrointestinal disorders 42. Probiotics, prebiotics including fiber, medicinal foods and motility 43. Systemic disorders that affect gastrointestinal motility
Authors
Satish S.C. Rao J . Harold Harrison MD, Distinguished University Chair in Gastroenterology,Professor of Medicine and Director, Neurogastroenterology/Motility,
Director, Digestive Health Clinical Research Center,
Medical College of Georgia, Augusta University, Augusta, GA, USA. Dr. Rao is professor at Georgia Regents University as well as chief of Gastroenterology/Hepatology and founding director of the Digestive Health Center and the GI Service Line. He is leading an initiative to expand the university's capabilities in treating digestive disorders that includes a new Digestive Health Center and neurogastroenterology and motility suite. He is working with colleagues in surgery, urology, otolaryngology, and neurology to create a model system of interdisciplinary care for GI motility patients. Dr. Rao is past president of the American Neurogastroenterology and Motility Society. He received the 3 highest honors from the American Gastroenterological Association: The Distinguished Clinician Award, the Masters Award for Outstanding Clinical Research, and the Distinguished Educator Award. He received the Auxiliary Research Award from the American College of Gastroenterology and several international awards for his research and teaching. He is cochair of AGA Council on Neurogastroenterology and GI Motility. Yeong Yeh Lee Professor of Medicine, Senior Consultant of Gastroenterology and Director of GI Function & Motility Lab, Universiti Sains Malaysia. Dr. Yeong Yeh Lee graduated from Universiti Sains Malaysia (USM) and continued his post-graduate training in internal medicine in the same institution. After his gastroenterology fellowship with the Ministry of Health of Malaysia, he went on to complete his PhD with Kenneth McColl at Glasgow, United Kingdom. Subsequently he did his post-doctoral fellowship with Satish Rao, co-editor and mentor, at Augusta University but also spent time at the University of North Carolina (UNC) Center for Functional GI & Motility Disorder with an award from the American College of Physicians. Currently, he is Professor of Medicine, Clinical Consultant and Director of GI Function & Motility Lab in his alma mater, USM. Dr. Lee serves as editors of several international journals and steering committee members of Malaysian Society of Gastroenterology and Hepatology, World Gastroenterology Organization and a few regional working groups but also the scientific chairs of meetings including Asian Pacific Digestive Week. He speaks regularly at international and local meetings. Dr. Lee also trained GI fellows and supervised PhDs and post-doctoral fellows. He has received many accolades including the AGA-Moti L. and Kamla Rustgi International Award 2012, the Outstanding Young Malaysian Award 2015 and most recently the Top Research Scientist of Malaysia 2018. He authored and co-authored 7 book chapters and more than 150 highly-cited articles. Uday C. Ghoshal Professor, Dept. Of Gastroenterolgy, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India. Dr. Uday C. Ghoshal graduated from the Burdwan Medical College, Burdwan, West Bengal, India in 1986 with University first position in all the three professional examinations and eight gold medals. He did his post-graduation (MD in Internal Medicine) from the Postgraduate Institute of Medical Education and Research, Chandigarh, India in 1991, and subsequently completed his post-doctorate fellowship in Gastroenterology (DM) from the Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India in 1994. After a period of working as a Consultant in the Department of Gastroenterology at the Institute of Post-Graduate Medical Education and Research at Kolkata, West Bengal, India, he joined Sanjay Gandhi Postgraduate Institute of Medical Sciences as Assistant Professor in 2000 where he has been working for the last two decades and is currently Professor in the Dept. of Gastroenterology in the same Institute where he founded and established a well-known Luminal Gastroenterology, GI motility, and functional GI disease unit and laboratory.
Dr. Ghoshal founded Asian Neurogastroenterology and Motility Association and the Indian Motility and Functional Diseases Association (currently the President of the latter). He also serves in the several committees of the Rome Foundation, in which, he is currently the Chair of the International Liaison and Research Committees. He is a Fellow of the American College of Gastroenterology, the Rome Foundation, and the National Academy of Medical Sciences (India). He has been invited as a faculty members in several national and international congresses. Dr. Ghoshal also trained a large number of GI fellows and has been guide for several DM and PhD students. He has edited one book on GI Motility, three patents, and serves as Associate Editor and Editorial Board Member of several international journals. Currently he is the Editor-in-Chief of the Indian Journal of Gastroenterology and has published 280 papers that are widely cited. He has received several national and international awards and orations.
