Molecular Evolutionary Models in Drug Discovery explores the application of evolutionary molecular models in drug discovery in which secondary metabolites play a fundamental role. Secondary metabolites are not produced in isolation, they are the result of the interaction of genes, metabolism and the environment. The book examines the role of secondary metabolites as leads in drug discovery and on the development of a rational bioprospecting model for new medicines based on the evolution of secondary metabolism. These evolutionary models are part of biological systems and are the most reliable expression of the functioning of living beings.
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Table of Contents
1. Introduction2. Molecular Autopoiesis3. Natural products and molecular networks4. Symbiogenesis autopoietic5. Metabolomic autopoiesis6. Clinical outcome and autopoiesis7. Toxical autopoiesis8. Future Research and Applications