Mass Spectrometry 2023 Market Opportunity Report

The Mass Spectrometry Instrumentation Market and End-User Insights

The mass spectrometry market has been one of the fastest growing and most innovative areas of analytical instrumentation over the past five years. Used to analyze the composition of materials, a wide variety of instrument types and techniques are used to detect and quantify everything from large macro-molecules to elemental composition with very high sensitivity. Understanding the breadth, dynamics, and future of this market is key for understanding the customers and markets that rely on these instruments.

Mass spectrometers (MS) measure the composition or makeup of various molecules, compounds, and materials by measuring the charge and mass ratio of ions derived from samples. Highly sensitive detection systems and analyzers provide measurements of the presence and prevalence of chemical components in a sample. Due to the wide variation in potential sample types and material composition, mass spectrometers have been developed with a wide variety of mass analyzers, formats, and couplings with other technologies.

The sample preparation and introduction methods chosen often determine the most suitable mass spec technique to use. Gas (GC) or liquid chromatography systems (LC) help separate gas and liquid phase materials and are often utilized in conjunction with mass spec analyzers. Other preparation techniques include those found in ICP-MS, which utilizes inductively coupled plasma (ICP) to ionize materials. Matrix assisted desorption ionization (MALDI) is another important preparation technique used for imaging surfaces. More recently, there has been a growing trend in ambient ionization mass spectrometers, which open the door for portable and environmental monitoring applications.

Mass spectrometry is subject to global macro-economic trends and regional economic trends. Mass spectrometer demand varies from region to region, with government investment, downstream market patterns, supply chain and production factors, and research opportunities all affecting device demand and growth. Regions such as the US & Canada and Europe feature advanced economies with growing or mature pharma/bio, academic, agricultural, and industrial sectors. The usage of mass spec technologies in these regions differs from the high growth economies of China and other Asia-Pacific countries. Additional world events such as wars, pandemics, and economic swings can all affect mass spectrometry demand. This report attempts to untangle the web of variables, helping understand these factors and the impacts they have on mass spec demand.

Several end markets rely heavily on mass spectrometry technologies. Academic institutions have long employed mass spectrometers for basic research and methods development, helping discover interactions in biological systems, identifying environmental contaminants or new bacterial strains, and understanding new metals and plastics. Other industries such as those that compose the pharma/bio sector utilize mass spectrometry for drug and biologics development, with analytical techniques such as time-of-flight (TOF), Fourier transform (FT), or Orbitrap becoming the go-to analytical tool for proteomic research and novel therapeutic development. The applied sector, consisting of clinical, general, environmental, food and agricultural, and forensics labs among others, utilize mass spectrometers for routine testing. Triple quadrupole mass spectrometers are the workhorses of many of these labs; such is the case in environmental labs for example, where these devices are the best instruments for detecting harmful plastics and Per- and Polyfluoroalkyl Substances (PFAS). MALDI instruments are being used in clinical labs to help identify new bacterial strains. Clinical diagnostics mass spectrometers are not covered in this report, but their research use only (RUO) counterparts are. Outside of research, there is a selection of industries that use mass spectrometers involved in process environments, such as in semiconductor production; products like these, such as RGAs, are also covered in this report.

Each mass spec technique has its selection of top vendors, with their products and moves in the market highlighted in this report. Other smaller vendors are not forgotten, as they often provide niche instruments or components that mass spec users have come to rely on. Unique to this report is a non-exhaustive product list that attempts to highlight the current product offerings from top mass spec vendors.

This report also contains a survey of mass spectrometry experts from a variety of backgrounds, regions, and industries. Here, they offer insights into the types of mass spectrometers they use, the types of labs they work in, and how they employ the devices they use. The research team delve into the applications utilizing mass spec, how often they use their devices, the vendors they buy from, and their satisfaction with those vendors.

This 2023 Mass Spectrometry Instrumentation Market Report covers the totality of the research and process of mass spectrometry instruments, observing market trends, influences, and forces that affect instrument demand and sales growth. As the leading provider of market research on analytical instrumentation, the publisher has crafted this report to evaluate and explain what is currently driving this important market.

Report Overview:

Market demand is segmented by technique, product type, region, industry, and function with yearly market forecasts through 2027 with commentary. Each technique also includes a non-exhaustive product list of current MS instruments.

The market estimates have been newly updated with 2022 as the base year and estimates are provided for the following techniques:

• GC/MS
• Quadruople LC/MS
• Time-of-flight LC/MS
• FT/MS & Ion trap LC/MS
• MALDI-TOF
• Magnetic Sector
• ICP-MS
• Ion Mobility Spectrometry
• Portable & In-Field MS
• Secondary Ion MS (SIMS)
• Mass Spec-Based Leak Detectors
• Residual Gas Analyzers (RGAs)
• Process MS

Market shares of participating suppliers in each technology category employed by the process analytical instrument industry.

Some of the top vendors in the overall market are presented below, in alphabetical order:

• 908 Devices
• Advion
• Agena Bioscience (Mesa Labs)
• Agilent
• Bruker
• CAMECA (AMETEK)
• Canon Anelva
• IMI Adaptas (IMI)
• Industrial gas suppliers
• Inficon
• ION-TOF
• JEOL
• LECO
• Leidos
• Leybold GmbH
• MKS Instruments
• Nu Instruments (AMETEK)
• PerkinElmer
• Pfeiffer Vacuum
• Rapiscan Systems (OSI Systems)
• SCIEX (Danaher)
• Shimadzu
• Smiths Detection
• Teledyne FLIR (Teledyne)
• Thermo Fisher Scientific
• ULVAC-PHI
• Waters

This report also includes a survey of 180 mass spectrometry end users, with the following information presented:

• Survey Demographics
• Mass Spectrometry Usage
• Overall Vendor Usage
• Overall Vendor Usage by Technology
• Future Purchasing

Additionally, vendor satisfaction from the following major MS vendors is presented, including insights into satisfaction by region, sector, product attribute, reasons for using said vendor, switching behavior, and improvements.

• Agilent
• Bruker
• PerkinElmer
• SCIEX
• Shimadzu
• Thermo Fisher Scientific
• Waters