Artificial Disc Replacement Systems - Medical Devices Pipeline Assessment, 2019

1.1 List of Tables
1.2 List of Figures

2.1 Artificial Disc Replacement Systems Overview

3.1 Artificial Disc Replacement Systems - Pipeline Products by Stage of Development
3.2 Artificial Disc Replacement Systems - Pipeline Products by Segment
3.3 Artificial Disc Replacement Systems - Pipeline Products by Territory
3.4 Artificial Disc Replacement Systems - Pipeline Products by Regulatory Path
3.5 Artificial Disc Replacement Systems - Pipeline Products by Estimated Approval Date
3.6 Artificial Disc Replacement Systems - Ongoing Clinical Trials

4.1 Artificial Disc Replacement Systems Companies - Pipeline Products by Stage of Development
4.2 Artificial Disc Replacement Systems - Pipeline Products by Stage of Development

5.1 ALCeraX Medizintechnik GmbH Company Overview
5.2 Articulus Bio LLC Company Overview
5.3 C.I. Takiron Corp Company Overview
5.4 City, University of London Company Overview
5.5 Disc Motion Technologies (Inactive) Company Overview
5.6 Globus Medical Inc Company Overview
5.7 Integra Spine Company Overview
5.8 K2M Inc Company Overview
5.9 Medical University of South Carolina Company Overview
5.10 Meliora Medical BV Company Overview
5.11 MiMedx Group Inc Company Overview
5.12 NEXUS TDR Inc Company Overview
5.13 Precision Spine Inc Company Overview
5.14 RE Spine, LLC Company Overview
5.15 SeaSpine, Inc. Company Overview
5.16 Simplify Medical, Inc. Company Overview
5.17 SINTX Technologies Inc Company Overview
5.18 Smart Disc, Inc. Company Overview
5.19 Spinal Kinetics Inc Company Overview
5.20 SpinalMotion Inc Company Overview
5.21 SpineSmith Holdings LLC Company Overview
5.22 TranS1 Inc Company Overview
5.23 TrueMotion Spine, Inc. Company Overview
5.24 University of South Florida Company Overview
5.25 Weill Cornell Medical College Company Overview
5.26 Zimmer Biomet Holdings Inc Company Overview

6.1 Aug 05, 2019: Orthofix names Jon Serbousek to Succeed CEO
6.2 Aug 05, 2019: Orthofix reports second quarter 2019 results
6.3 Aug 01, 2019: RTI Surgical announces second quarter 2019 results
6.4 Aug 01, 2019: Globus Medical reports second quarter 2019 results
6.5 Jul 30, 2019: NuVasive announces second quarter 2019 financial results
6.6 Jul 30, 2019: CryoLife reports second quarter 2019 financial results
6.7 Jul 26, 2019: Zimmer Biomet announces second quarter 2019 financial results
6.8 Jul 25, 2019: Stryker reports second quarter 2019 operating results
6.9 Jul 24, 2019: Integra LifeSciences reports second quarter 2019 financial results
6.10 Jul 24, 2019: Former Medtronic Executive Sean Ginney named VP of Sales at Current Health
6.11 Jul 24, 2019: Alphatec reports second quarter 2019 financial results and corporate highlights
6.12 Jul 09, 2019: Medicrea reports first half 2019 sales
6.13 Jun 27, 2019: Globus Medical appoints Keith Pfeil as Senior Vice President and CFO
6.14 Jun 27, 2019: Alphatec announces organizational and corporate updates
6.15 Jun 24, 2019: Integra LifeSciences announces promotion of Glenn Coleman to newly-created role of chief operating officer and appointment of Carrie Anderson as chief financial officer
6.16 Jun 19, 2019: Zimmer Biomet announces chief financial officer transition plan
6.17 Jun 14, 2019: Stryker to invest €200m in RD&I projects in Ireland
6.18 Jun 05, 2019: MiMedx issues new presentation for investors in advance Of 2018 Annual Meeting
6.19 Jun 04, 2019: Medtronic awarded $150M contract from Defense Logistics Agency
6.20 May 30, 2019: MiMedx announces comprehensive board refreshment plan in cooperation with prescience point
6.21 May 30, 2019: Nuvasive SpineTRACK Registry successfully meets 2018 medicare reporting requirements for merit-based incentive payments system
6.22 May 23, 2019: Medtronic announces fiscal year and fourth quarter 2019 financial results
6.23 May 21, 2019: Brand new artificial cervical disc means no more pain or stiff necks
6.24 May 17, 2019: Medicrea announces first quarter 2019 financial results
6.25 May 09, 2019: MiMedx appoints Timothy R. Wright as Chief Executive Officer
6.26 May 09, 2019: Alphatec reports first quarter 2019 financial results and corporate highlights
6.27 May 06, 2019: Orthofix reports first quarter 2019 results
6.28 May 02, 2019: Globus Medical announces first quarter 2019 results
6.29 May 02, 2019: Globus Medical reports first quarter 2019 results
6.30 May 02, 2019: RTI Surgical announces first quarter 2019 results
6.31 May 01, 2019: NuVasive announces first quarter 2019 financial results
6.32 Apr 30, 2019: CryoLife Reports First Quarter 2019 Financial Results
6.33 Apr 26, 2019: Zimmer Biomet announces first quarter 2019 financial results
6.34 Apr 24, 2019: Integra LifeSciences reports first quarter 2019 financial results
6.35 Apr 23, 2019: Orthofix announces first US patient implants following FDA approval of the M6-C Artificial Cervical Disc designed to treat cervical disc degeneration
6.36 Apr 23, 2019: Stryker announces first quarter 2019 operating results
6.37 Apr 15, 2019: Alphatec Announces Sales Leadership Appointment And Successful Closing Of Expanded Credit Facility With Squadron Capital
6.38 Apr 15, 2019: SINTX Technologies hires strategic VP
6.39 Apr 10, 2019: Medicrea reports first quarter 2019 sales
6.40 Apr 04, 2019: Full two-year data from Orthofix M6-C Artificial Cervical Disc study shows significant improvement in pain, function and quality of life scores
6.41 Apr 02, 2019: Updated NASS position on lumbar artificial disc replacement matches Centinel Spine's prodisc L Indications
6.42 Mar 27, 2019: Stryker announces new Vice President, chief legal officer
6.43 Mar 25, 2019: Medtronic launches Medtech Innovation Accelerator in Shanghai
6.44 Mar 22, 2019: Medicrea announces 2018 annual results
6.45 Mar 14, 2019: Medtronic names Andrea J. Goldsmith as a new director
6.46 Mar 08, 2019: RTI Surgical announces appointment of Jeffrey C. Lightcap to Board of Directors
6.47 Mar 07, 2019: MCRA assists with premarket approval of the M6-C Artificial Cervical Disc
6.48 Mar 07, 2019: Simplify Medical announces 60th U.S. patent for innovative cervical disc replacement portfolio
6.49 Feb 28, 2019: RTI Surgical announces fourth quarter and full year 2018 results
6.50 Feb 21, 2019: Integra LifeSciences reports fourth quarter and full-year 2018 financial results and provides 2019 financial guidance
6.51 Feb 21, 2019: Globus Medical reports full year and fourth quarter 2018 Results
6.52 Feb 20, 2019: NuVasive reports fourth quarter and full year 2018 financial results
6.53 Feb 19, 2019: Medtronic reports third quarter financial results
6.54 Feb 13, 2019: CryoLife Reports Fourth Quarter and Full Year 2018 Financial Results
6.55 Feb 07, 2019: Orthofix announces FDA approval of the M6-C Artificial Cervical Disc to treat patients with Cervical Disc Degeneration
6.56 Feb 05, 2019: Spine Journal publishes study that confirms benefits of LP-ESP disc replacement prosthesis from FH Orthopedics
6.57 Feb 01, 2019: Zimmer Biomet announces fourth quarter and full-year 2018 financial results
6.58 Jan 29, 2019: Stryker reports 2018 results and 2019 outlook
6.59 Jan 24, 2019: Globus Medical’s SECURE C Cervical Artificial Disc receives expanded Insurance Coverage
6.60 Jan 16, 2019: Medicrea reports 2018 fourth quarter and annual sales
6.61 Jan 09, 2019: Medtronic Foundation Recognizes 12 Bakken Invitation Honorees for Driving Positive Change in Healthcare
6.62 Jan 09, 2019: Integra LifeSciences appoints Rhonda Germany Ballintyn as Director
6.63 Jan 08, 2019: Integra LifeSciences announces preliminary fourth quarter 2018 financial results
6.64 Jan 08, 2019: Orthofix announces preliminary 2018 fourth quarter and full year net sales results
6.65 Jan 08, 2019: Globus Medical reports preliminary record fourth quarter and full year sales results
6.66 Jan 07, 2019: NuVasive Announces Preliminary Unaudited Fourth Quarter And Full Year 2018 Revenue Results
6.67 Jan 07, 2019: Alphatec announces 2018 preliminary revenue results, 2019 revenue outlook, and senior leadership changes
6.68 Jan 03, 2019: NuVasive CEO J. Christopher Barry announces new organizational structure and Leadership Team
6.69 Dec 18, 2018: Centinel Spine in the News: Spine surgeon becomes first in Western Pennsylvania to reintroduce Lumbar Artificial Disc
6.70 Dec 10, 2018: Medtronic named one of America's Best Corporate Citizens in 2018 by Forbes Magazine
6.71 Dec 05, 2018: MiMedx Announces Leadership Changes And Promotions
6.72 Dec 05, 2018: MiMedx Announces Organizational Realignment Program
6.73 Nov 20, 2018: Medtronic reports financial results of second quarter of fiscal year 2019
6.74 Nov 15, 2018: Medicrea reports third-quarter results
6.75 Nov 14, 2018: Simplify Medical completes enrollment in U.S. IDE pivotal trial of Simplify Disc for two-level cervical disc replacement
6.76 Nov 12, 2018: Integra LifeSciences names Eric Schwartz, Corporate Vice President, General Counsel and Secretary
6.77 Nov 08, 2018: Alphatec reports third quarter 2018 financial and corporate highlights
6.78 Nov 08, 2018: Globus Medical reports third quarter 2018 results
6.79 Nov 08, 2018: Medtronic delivers significant progress on global corporate citizenship efforts
6.80 Nov 01, 2018: RTI Surgical announces third quarter 2018 results
6.81 Oct 31, 2018: Integra LifeSciences reports third quarter 2018 financial results
6.82 Oct 31, 2018: Zimmer Biomet appoints Ivan Tornos as Group President, Orthopedics
6.83 Oct 31, 2018: CryoLife reports third quarter 2018 results
6.84 Oct 30, 2018: NuVasive announces third quarter 2018 financial results
6.85 Oct 29, 2018: Orthofix Medical announces third quarter 2018 financial results
6.86 Oct 26, 2018: Zimmer Biomet announces third quarter 2018 financial results
6.87 Oct 25, 2018: Stryker reports third quarter 2018 operating results
6.88 Oct 19, 2018: Zimmer Biomet Launches Mobi-C in Japan
6.89 Oct 19, 2018: NuVasive Names J. Christopher Barry To Succeed Gregory T. Lucier As Chief Executive Officer; Lucier To Remain Chairman Of The Board
6.90 Oct 18, 2018: Simplify Medical appoints IP Attorney Veteran to VP, General Counsel
6.91 Oct 13, 2018: Johnson Fistel Announces Investigations of Zimmer Biomet Holdings and Acadia Healthcare Company
6.92 Oct 08, 2018: Stryker names Meenakshi Nevatia as New MD for India
6.93 Oct 04, 2018: NuVasive to showcase comprehensive solutions for complex spinal deformities at Scoliosis Research Society Annual Meeting
6.94 Sep 28, 2018: SEC charges Stryker a second time for FCPA violations
6.95 Sep 27, 2018: Alphatec Accelerates Organic Innovation Machine With Addition of Key Senior Leadership and Expansion of Market Development Team
6.96 Sep 24, 2018: Zimmer Biomet opens new location near CEO's hometown: 3 highlights
6.97 Sep 21, 2018: Scott Huennekens To Join NuVasive Board Of Directors
6.98 Sep 20, 2018: Medicrea announces Eurospine 2018 presence and highlights a recently published study validating its predictive modelling approach for AIS patients
6.99 Sep 19, 2018: Medicrea announces first half 2018 results
6.100 Sep 17, 2018: Simplify Medical Technology selected for Innovative Technology paper at NASS 2018 Annual Meeting

7.1 Methodology
7.2 About the Author
7.3 Contact Us
7.4 Disclaimer

Table 1: Artificial Disc Replacement Systems - Pipeline Products by Stage of Development
Table 2: Artificial Disc Replacement Systems - Pipeline Products by Segment
Table 3: Artificial Disc Replacement Systems - Pipeline Products by Territory
Table 4: Artificial Disc Replacement Systems - Pipeline Products by Regulatory Path
Table 5: Artificial Disc Replacement Systems - Pipeline Products by Estimated Approval Date
Table 6: Artificial Disc Replacement Systems - Ongoing Clinical Trials
Table 7: Artificial Disc Replacement Systems Companies - Pipeline Products by Stage of Development
Table 8: Artificial Disc Replacement Systems - Pipeline Products by Stage of Development
Table 9: ALCeraX Medizintechnik GmbH Pipeline Products & Ongoing Clinical Trials Overview
Table 10: ConCera - Product Status
Table 11: ConCera - Product Description
Table 12: Articulus Bio LLC Pipeline Products & Ongoing Clinical Trials Overview
Table 13: Cervical/Lumbar Spine Artificial Disc - Product Status
Table 14: Cervical/Lumbar Spine Artificial Disc - Product Description
Table 15: C.I. Takiron Corp Pipeline Products & Ongoing Clinical Trials Overview
Table 16: FABRICUBE - Product Status
Table 17: FABRICUBE - Product Description
Table 18: City, University of London Pipeline Products & Ongoing Clinical Trials Overview
Table 19: Artificial Intervertebral Disc Prosthesis - Product Status
Table 20: Artificial Intervertebral Disc Prosthesis - Product Description
Table 21: Disc Motion Technologies (Inactive) Pipeline Products & Ongoing Clinical Trials Overview
Table 22: Inlign PL - Product Status
Table 23: Inlign PL - Product Description
Table 24: Globus Medical Inc Pipeline Products & Ongoing Clinical Trials Overview
Table 25: Triumph Lumbar Disc - Product Status
Table 26: Triumph Lumbar Disc - Product Description
Table 27: Integra Spine Pipeline Products & Ongoing Clinical Trials Overview
Table 28: eDISC - Product Status
Table 29: eDISC - Product Description
Table 30: K2M Inc Pipeline Products & Ongoing Clinical Trials Overview
Table 31: Physio-L - Product Status
Table 32: Physio-L - Product Description
Table 33: Medical University of South Carolina Pipeline Products & Ongoing Clinical Trials Overview
Table 34: Artificial Intervertebral Disc - Product Status
Table 35: Artificial Intervertebral Disc - Product Description
Table 36: Meliora Medical BV Pipeline Products & Ongoing Clinical Trials Overview
Table 37: Artificial Lumbar Disc Prosthesis - Back Pain - Product Status
Table 38: Artificial Lumbar Disc Prosthesis - Back Pain - Product Description
Table 39: Zenith-C - Product Status
Table 40: Zenith-C - Product Description
Table 41: MiMedx Group Inc Pipeline Products & Ongoing Clinical Trials Overview
Table 42: SaluDisc - Product Status
Table 43: SaluDisc - Product Description
Table 44: NEXUS TDR Inc Pipeline Products & Ongoing Clinical Trials Overview
Table 45: FlexBac - Product Status
Table 46: FlexBac - Product Description
Table 47: Precision Spine Inc Pipeline Products & Ongoing Clinical Trials Overview
Table 48: Disc Replacement Device - Product Status
Table 49: Disc Replacement Device - Product Description
Table 50: RE Spine, LLC Pipeline Products & Ongoing Clinical Trials Overview
Table 51: Intervertebral Disc - Product Status
Table 52: Intervertebral Disc - Product Description
Table 53: SeaSpine, Inc. Pipeline Products & Ongoing Clinical Trials Overview
Table 54: Catalina - Product Status
Table 55: Catalina - Product Description
Table 56: La Jolla - Product Status
Table 57: La Jolla - Product Description
Table 58: Simplify Medical, Inc. Pipeline Products & Ongoing Clinical Trials Overview
Table 59: Simplify Disc - Product Status
Table 60: Simplify Disc - Product Description
Table 61: Simplify Medical, Inc. - Ongoing Clinical Trials Overview
Table 62: Simplify Disc - Clinical Study Protocol for the Investigation of the Simplify Cervical Artificial Disc
Table 63: Simplify Disc - Clinical Study Protocol for the Investigation of the Two Level Simplify Cervical Artificial Disc
Table 64: SINTX Technologies Inc Pipeline Products & Ongoing Clinical Trials Overview
Table 65: Spartacus - Product Status
Table 66: Spartacus - Product Description
Table 67: Smart Disc, Inc. Pipeline Products & Ongoing Clinical Trials Overview
Table 68: Spinal Replacement Disc - Product Status
Table 69: Spinal Replacement Disc - Product Description

Figure 1: Artificial Disc Replacement Systems - Pipeline Products by Stage of Development
Figure 2: Artificial Disc Replacement Systems - Pipeline Products by Segment
Figure 3: Artificial Disc Replacement Systems - Pipeline Products by Territory
Figure 4: Artificial Disc Replacement Systems - Pipeline Products by Regulatory Path
Figure 5: Artificial Disc Replacement Systems - Pipeline Products by Estimated Approval Date
Figure 6: Artificial Disc Replacement Systems - Ongoing Clinical Trials