Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents provides sound data on the utility of biological and plant-based drugs and describes challenges faced in all aspects offering indispensable strategies to use in the development of bioactive medicines. Bioactive based medications are commonly used throughout the world and have been recognized by physicians and patients for their therapeutic efficacy. Bioactive formulations, including their subordinates and analogs, address 50% of all medicines in clinical practice. Novel bioactive medicine transporters can cure many disorders by both spatial and transitory approaches and have various justifications in medicinal potential.
This book presents information on the utility of natural, plant, animal and bioengineered bioactive materials. It is a fundamental source of information and data for pharmacognosists, pharmaceutical analysts, drug transport scientists and pharmacologists working in bioactive medications.
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Table of Contents
1. Challenges and Need of Delivery carriers for bioactives and Biological agents: An Introduction
2. Natural product-based nanomedicine: polymeric nanocapsules as delivery cargoes of food bioactives and nutraceuticals for anticancer purposes
3. The promising expedition of the delivery systems for monoclonal antibodies
4. Innovative technological systems to optimize the delivery and therapeutic activity of antimicrobial drugs
5. Tailoring Drug and Gene Co-delivery Nanosystems for Glioblastoma Treatment
6. Polyelectrolyte multilayers for delivery of bioactives
7. Magnetic nanocarriers of bioactives: structural and delivery system designs
8. Iron bond bovine lactoferrin for treatment of anaemia associated with cancer cachexia
9. Metallic-based nanocarriers: Methods employed in nanoparticle characterization and assessing the interaction with the blood-brain barrier
10. Inorganic-based drug delivery systems of bioactives for cancer therapy
11. Novel perspectives for treatment of brain diseases with bioactives
12. Nanoparticle-based delivery of polyphenols for the treatment of inflammation-associated diseases
13. Efficacy of promising flavonoids from Festuca, Lonicera, and Acacia genera against Glioblastoma Multiform: potential for the Dandenong Ranges of Victoria, Australia
14. Targeting aspects for bioactive drugs
15. Amphiphilic Block Co Polymers: A Smart option for Bioactives delivery
16. Rheumatoid Arthritis: Basic Pathophysiology and role of chitosan nanoparticles in therapy
17. Targeted delivery through Carbon nanomaterials: Applications in bioactive delivery system
18. Liposomes and Phytosomes for Phytoconstituents
19. Quality by Design and Formulation optimization using statistical tools for safe and efficient bioactive loading
20. Commercial aspects and market potential of novel delivery systems for bioactives
Authors
Manju Rawat Singh Assistant Professor (Senior), University Institute of Pharmacy, Pt. Ravishankar Shukla University, India.
Dr. Manju Singh obtained her M.Pharm in Pharmaceutical biotechnology from the Department of Pharmaceutical sciences, Dr. H.S. Gour Central University, Sagar in 2004 and Ph.D from University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur (C.G.) India in 2009 where she is currently working as assistant professor. She has around 18 years of teaching and research experience. Her prime research area includes designing strategies for protein and peptide delivery, topical systems for autoimmune disorders like psoriasis, rheumatoid arthritis, inflammatory bowel disease and experimental designing using advanced statistical and mathematical modeling methods. She has 80 research and review papers published in national and international journals. She has citations more than 3000 with h-index 28 and i10 index of 49 (Google scholar) and scopus h-index 21; 4100 citations. She has 2 international and 1 Indian patent. She has successfully completed several projects funded by Indian council of medical research (ICMR), university grants commission (UGC), C.G. state council of science and technology (CGCOST), and Department of science and technology (DST). She is recipient of DHR-ICMR international fellowship 2014-15 and number of awards at national and state level for excellence in research viz. Young scientist award of the state of Chhattisgarh 2006 in biotechnology. She has been bestowed with Best Teacher award (Assistant Professor) of Pt. Ravishankar Shukla University in science section 2016. She is a life member of various professional bodies like Indian Pharmaceutical association (IPA), Association of Pharmacy teachers of India (APTI), Indian Pharmacy Graduates Association (IPGA). She had been visiting scientist at School of Pharmacy, Department of Pharmaceutics, University of Mississippi, Oxford, USA 2015. She is engaged in research projects focused on studying the role of plant bioactives in devising new treatments mainly for autoimmune disorders and inflammatory diseases in collaboration with various universities in India and abroad.
Deependra Singh Assistant Professor (Senior), University Institute of Pharmacy, Pt. Ravishankar Shukla University, India.
Dr. Deependra Singh is presently working as assistant professor at University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur (C.G.) India. He is a central member of the Pharmacy council of India. He has around 18 years of teaching and research experience. His prime research area includes formulation of multiple bioactive delivery systems like multiphase hydrogels, nanosystems, microspheres for wound management, advanced statistical and mathematical modelling methods, Tissue Culture Techniques, nutraceuticals and designing novel systems for plant actives and extracts. He has more than 90 research and review papers published in national and international journals. He has successfully completed projects funded by UGC, AICTE, DST and several industrial projects. He has citations more than 4000 with h-index 28 and i10 index of 49 (Google scholar) and scopus h-index 21; 4100 citations. He has 2 international and 1 Indian patent. He is recipient of prestigious Department of health research-ICMR young Indian biomedical scientist award 2019, UGC RAMAN international award 2014 and UGC Research Award 2012 by university Grants Commission, New Delhi. He has prestigious awards at state level for excellence in research viz.; Young scientist award of the state of Chhattisgarh 2006 in medical sciences. He is state evaluator and trainee for national children science congress. He is a life member of various professional bodies like Indian Pharmaceutical association (IPA), Association of Pharmacy teachers of India (APTI), Indian Society of Pharmacognosy (ISP) and serving as President, Chhattisgarh state branch APTI 2013 (Elected); Secretary, Chhattisgarh state branch IPA. He had been visiting scientist at National Center for Natural Products Research, School of Pharmacy, University of Mississippi, Mississippi USA.
Jagat Kanwar Professor and Laboratory Head, Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research (NLIMBR) in School of Medicine, Faculty of Health, Deakin University, Australia.
Dr. Jagat Kanwar is Professor is the group leader and laboratory head of Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research (NLIMBR) in School of Medicine, Faculty of Health at Deakin University, Australia. He has an international reputation in investigating fundamental and applied molecular aspects of cancer and chronic inflammation. He is an immunologist, molecular biologist and cell biologist. He has extensive training and expertise in studying the molecular mechanisms and in devising treatments for human diseases like cancer and chronic inflammatory diseases in both in vivo and in vitro models. His work has generated 12 patents/PCTs. Five of these patents have been licensed for commercialisation to biotech companies Antisoma, UK; Neurenpharma and NeuronZ, NZ. His research findings led to the development of novel ice-cream product 'ReCharge' with bovine lactoferrin and iron saturated milk lactoferrin as key ingredient and designated as the first medical food.
Nagendra Singh Chauhan Senior Scientific Officer Grade-II and Government Analyst, Drugs Testing Laboratory avam Anusandhan Kendra Raipur, India.
Dr. Nagendra Singh Chauhan obtained his MPharm and PhD from the Department of Pharmaceutical Sciences at Dr. Harisingh Gour University in Sagar, India. He has about 15 years of research experience and has professional expertise in natural product isolation. He is presently working as a senior scientific officer grade-II and government analyst at Drugs Testing Laboratory Avam Anusandhan Kendra, Raipur, Chhattisgarh, India. He has written more than 65 articles and 24 book chapters and has edited 4 books with publishers like Academic Press, CRC, and Wiley. He is a member of various professional and academic bodies like the Society of Pharmacognosy, International Natural Product Sciences Taskforce (INPST), Societ� Italo-Latinoamericana di Etnomedicina (SILAE), Institutional Human Ethics Committee, and Association of Pharmaceutical Teachers of India (APTI).
