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Giant-Cell Arteritis - Market Insight, Epidemiology and Market Forecast -2032

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    Report

  • 150 Pages
  • January 2022
  • Region: Global
  • DelveInsight
  • ID: 4871920
UP TO OFF until Dec 31st 2024
This "Giant-Cell Arteritis- Market Insights, Epidemiology, and Market Forecast-2032" report delivers an in-depth understanding of the Giant-Cell Arteritis, historical and forecasted epidemiology as well as the Giant-Cell Arteritis market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

The Giant-Cell Arteritis market report provides current treatment practices, emerging drugs, Giant-Cell Arteritis market share of the individual therapies, current and forecasted Giant-Cell Arteritis market Size from 2019 to 2032 segmented by seven major markets. The Report also covers current Giant-Cell Arteritis treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assesses the underlying potential of the market.

Geography Covered

  • The United States
  • EU5 (Germany, France, Italy, Spain, and the United Kingdom)
  • Japan

Study Period: 2019-2032

Giant-Cell Arteritis Disease Understanding and Treatment Algorithm


The Giant-Cell Arteritis market report gives a thorough understanding of the Giant-Cell Arteritis by including details such as disease definition, symptoms, causes, pathophysiology, diagnosis and treatment.

Diagnosis


This segment of the report covers the detailed diagnostic methods or tests for Giant-Cell Arteritis.

Treatment


It covers the details of conventional and current medical therapies available in the Giant-Cell Arteritis market for the treatment of the condition. It also provides Giant-Cell Arteritis treatment algorithms and guidelines in the United States, Europe, and Japan.

Giant-Cell Arteritis Epidemiology


The Giant-Cell Arteritis epidemiology division provide insights about historical and current Giant-Cell Arteritis patient pool and forecasted trend for every seven major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of The report also provides the diagnosed patient pool and their trends along with assumptions undertaken.

Key Findings


The disease epidemiology covered in the report provides historical as well as forecasted Giant-Cell Arteritis epidemiology scenario in the 7MM covering the United States, EU5 countries (Germany, Spain, Italy, France, and the United Kingdom), and Japan from 2019 to 2032.

Country Wise- Giant-Cell Arteritis Epidemiology


The epidemiology segment also provides the Giant-Cell Arteritis epidemiology data and findings across the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.

Giant-Cell Arteritis Drug Chapters


Drug chapter segment of the Giant-Cell Arteritis report encloses the detailed analysis of Giant-Cell Arteritis marketed drugs and late stage (Phase-III and Phase-II) pipeline drugs. It also helps to understand the Giant-Cell Arteritis clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug and the latest news and press releases.

Marketed Drugs


The report provides the details of the marketed product available for Giant-Cell Arteritis treatment.

Giant-Cell Arteritis Emerging Drugs


The report provides the details of the emerging therapies under the late and mid-stage of development for Giant-Cell Arteritis treatment.

Giant-Cell Arteritis Market Outlook


The Giant-Cell Arteritis market outlook of the report helps to build the detailed comprehension of the historic, current, and forecasted Giant-Cell Arteritis market trends by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand of better technology.

This segment gives a thorough detail of Giant-Cell Arteritis market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on annual cost of therapy, inclusion and exclusion criteria's, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated market data are presented with relevant tables and graphs to give a clear view of the market at first sight.

According to the publisher, Giant-Cell Arteritis market in 7MM is expected to change in the study period 2019-2032.

Key Findings


This section includes a glimpse of the Giant-Cell Arteritis market in 7MM.

The United States Market Outlook


This section provides the total Giant-Cell Arteritis market size and market size by therapies in the United States.

EU-5 Countries: Market Outlook


The total Giant-Cell Arteritis market size and market size by therapies in Germany, France, Italy, Spain, and the United Kingdom is provided in this section.

Japan Market Outlook


The total Giant-Cell Arteritis market size and market size by therapies in Japan is also mentioned.

Giant-Cell Arteritis Drugs Uptake


This section focusses on the rate of uptake of the potential drugs recently launched in the Giant-Cell Arteritis market or expected to get launched in the market during the study period 2019-2032. The analysis covers Giant-Cell Arteritis market uptake by drugs; patient uptake by therapies; and sales of each drug.

This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allow the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

Giant-Cell Arteritis Pipeline Development Activities


The report provides insights into different therapeutic candidates in Phase II, and Phase III stage. It also analyses Giant-Cell Arteritis key players involved in developing targeted therapeutics.

Pipeline Development Activities


The report covers the detailed information of collaborations, acquisition and merger, licensing, patent details and other information for Giant-Cell Arteritis emerging therapies.

Reimbursement Scenario in Giant-Cell Arteritis


Approaching reimbursement proactively can have a positive impact both during the late stages of product development and well after product launch. In a report, we take reimbursement into consideration to identify economically attractive indications and market opportunities. When working with finite resources, the ability to select the markets with the fewest reimbursement barriers can be a critical business and price strategy.

KOL-Views


To keep up with current market trends, we take KOLs and SME's opinion working in Giant-Cell Arteritis domain through primary research to fill the data gaps and validate our secondary research. Their opinion helps to understand and validate current and emerging therapies treatment patterns or Giant-Cell Arteritis market trend. This will support the clients in potential upcoming novel treatment by identifying the overall scenario of the market and the unmet needs.

Competitive Intelligence Analysis


The publisher performs Competitive and Market Intelligence analysis of the Giant-Cell Arteritis Market by using various Competitive Intelligence tools that include - SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies etc. The inclusion of the analysis entirely depends upon the data availability.

Scope of the Report

  • The report covers the descriptive overview of Giant-Cell Arteritis, explaining its causes, signs and symptoms, pathophysiology, diagnosis and currently available therapies
  • Comprehensive insight has been provided into the Giant-Cell Arteritis epidemiology and treatment in the 7MM
  • Additionally, an all-inclusive account of both the current and emerging therapies for Giant-Cell Arteritis are provided, along with the assessment of new therapies, which will have an impact on the current treatment landscape
  • A detailed review of Giant-Cell Arteritis market; historical and forecasted is included in the report, covering drug outreach in the 7MM
  • The report provides an edge while developing business strategies, by understanding trends shaping and driving the global Giant-Cell Arteritis market

Report Highlights

  • In the coming years, Giant-Cell Arteritis market is set to change due to the rising awareness of the disease, and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market
  • The companies and academics are working to assess challenges and seek opportunities that could influence Giant-Cell Arteritis R&D. The therapies under development are focused on novel approaches to treat/improve the disease condition
  • Major players are involved in developing therapies for Giant-Cell Arteritis. Launch of emerging therapies will significantly impact the Giant-Cell Arteritis market
  • A better understanding of disease pathogenesis will also contribute to the development of novel therapeutics for Giant-Cell Arteritis
  • Our in-depth analysis of the pipeline assets across different stages of development (Phase III and Phase II), different emerging trends and comparative analysis of pipeline products with detailed clinical profiles, key cross-competition, launch date along with product development activities will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities

Giant-Cell Arteritis Report Insights

  • Patient Population
  • Therapeutic Approaches
  • Giant-Cell Arteritis Pipeline Analysis
  • Giant-Cell Arteritis Market Size and Trends
  • Market Opportunities
  • Impact of upcoming Therapies

Giant-Cell Arteritis Report Key Strengths

  • 11 Years Forecast
  • 7MM Coverage
  • Giant-Cell Arteritis Epidemiology Segmentation
  • Key Cross Competition
  • Highly Analyzed Market
  • Drugs Uptake

Giant-Cell Arteritis Report Assessment


Current Treatment Practices
  • Unmet Needs
  • Pipeline Product Profiles
  • Market Attractiveness
  • Market Drivers and Barriers

Key Questions Answered


Market Insights:

  • What was the Giant-Cell Arteritis market share (%) distribution in 2019 and how it would look like in 2032?
  • What would be the Giant-Cell Arteritis total market size as well as market size by therapies across the 7MM during the forecast period (2019-2032)?
  • What are the key findings pertaining to the market across 7MM and which country will have the largest Giant-Cell Arteritis market size during the forecast period (2019-2032)?
  • At what CAGR, the Giant-Cell Arteritis market is expected to grow in 7MM during the forecast period (2019-2032)?
  • What would be the Giant-Cell Arteritis market outlook across the 7MM during the forecast period (2019-2032)?
  • What would be the Giant-Cell Arteritis market growth till 2032, and what will be the resultant market Size in the year 2032?
  • How would the market drivers, barriers and future opportunities affect the market dynamics and subsequent analysis of the associated trends?

Epidemiology Insights:

  • What is the disease risk, burden and unmet needs of the Giant-Cell Arteritis?
  • What is the historical Giant-Cell Arteritis patient pool in seven major markets covering the United States, EU5 (Germany, Spain, France, Italy, UK), and Japan?
  • What would be the forecasted patient pool of Giant-Cell Arteritis in seven major markets covering the United States, EU5 (Germany, Spain, France, Italy, UK), and Japan?
  • What will be the growth opportunities in the 7MM with respect to the patient population pertaining to Giant-Cell Arteritis?
  • Out of all 7MM countries, which country would have the highest prevalent population of Giant-Cell Arteritis during the forecast period (2019-2032)?
  • At what CAGR the population is expected to grow in 7MM during the forecast period (2019-2032)?

Current Treatment Scenario, Marketed Drugs and Emerging Therapies:

  • What are the current options for the Giant-Cell Arteritis treatment, along with the approved therapy?
  • What are the current treatment guidelines for the treatment of Giant-Cell Arteritis in the USA, Europe, and Japan?
  • What are the Giant-Cell Arteritis marketed drugs and their MOA, regulatory milestones, product development activities, advantages, disadvantages, safety and efficacy, etc.?
  • How many companies are developing therapies for the treatment of Giant-Cell Arteritis?
  • How many therapies are developed by each company for Giant-Cell Arteritis treatment?
  • How many are emerging therapies in mid-stage, and late stage of development for Giant-Cell Arteritis treatment?
  • What are the key collaborations (Industry - Industry, Industry - Academia), Mergers and acquisitions, licensing activities related to the Giant-Cell Arteritis therapies?
  • What are the recent novel therapies, targets, mechanisms of action and technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Giant-Cell Arteritis and their status?
  • What are the key designations that have been granted for the emerging therapies for Giant-Cell Arteritis?
  • What are the global historical and forecasted market of Giant-Cell Arteritis?

Reasons to Buy

  • The report will help in developing business strategies by understanding trends shaping and driving the Giant-Cell Arteritis market
  • To understand the future market competition in the Giant-Cell Arteritis market and Insightful review of the key market drivers and barriers
  • Organize sales and marketing efforts by identifying the best opportunities for Giant-Cell Arteritis in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom) and Japan
  • Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors
  • Organize sales and marketing efforts by identifying the best opportunities for Giant-Cell Arteritis market
  • To understand the future market competition in the Giant-Cell Arteritis market

Table of Contents

1. Key Insights2. Report Introduction
3. Giant Cell Arteritis Disease Market Overview at a Glance
3.1. Market Share (%) Distribution of Giant Cell Arteritis in 2018
3.2. Market Share (%) Distribution of Giant Cell Arteritis in 2030
4. Executive Summary of Giant Cell Arteritis (GCA)
4.1. Key Events
5. Epidemiology and Market Methodology
6. Disease Background and Overview
6.1. Introduction
6.2. Causes of GCA
6.3. Signs and symptoms of GCA
6.4. Complications of GCA
6.5. Clinical Manifestations of GCA
6.6. Pathophysiology of GCA
6.7. Pathogenesis of GCA
7. Diagnosis of Giant Cell Arteritis (GCA)
7.1. Diagnostic Algorithm
7.1.1. Journal of Medical Case Reports diagnostic algorithm
7.2. Diagnostic Criteria
7.3. Diagnosis Tests
7.3.1. Physical Examination
7.3.2. Blood Tests
7.3.3. Imaging Tests
7.3.4. Temporal artery biopsy (TAB)
7.4. Differential Diagnosis
8. Diagnostic guidelines
8.1. American College of Rheumatology (ACR) diagnostic guidelines for GCA
8.2. European League against Rheumatism (EULAR) guidelines for the diagnosis of GCA
8.3. The British Society for Rheumatology (BSR) and British Health Professionals in Rheumatology (BHPR) diagnostic guidelines for GCA
8.4. The French Study Group for Larger vessel vasculitis (GEFA) recommendations for diagnosis of GCA
9. Treatment of GCA
9.1. Treatment Algorithm of GCA
9.2. Corticosteroids
9.3. Disease-modifying anti-rheumatic drugs (DMARDs)
9.3.1. Methotrexate (MTX)
9.3.2. Leflunomide
9.3.3. Azathioprine
10. Treatment Guidelines
10.1. American college of rheumatology treatment guidelines for the management of GCA
10.2. European League against Rheumatism (EULAR) guidelines for the management of GCA
10.3. The British Society for Rheumatology (BSR) and British Health Professionals in Rheumatology (BHPR) treatment guidelines for GCA
10.4. The French Study Group for Larger vessel vasculitis (GEFA) recommendations for management of GCA
11. Epidemiology and Patient Population
11.1. Key Findings
11.2. Epidemiology of Giant Cell Arteritis
11.3. Epidemiology Scenario
11.3.1. Total Prevalent Cases of Giant Cell Arteritis
11.3.2. Total Subtype-specific Cases of Giant Cell Arteritis
11.3.3. Total Age group-specific Cases of Giant Cell Arteritis
11.3.4. Total Clinical Manifestation-specific Cases of Giant Cell Arteritis
11.3.5. Total Treated Cases of Giant Cell Arteritis
12. Patient Journey of Giant Cell Arteritis (GCA)13. Key Endpoints in Giant Cell Arteritis (GCA) Clinical Trials
14. Marketed Therapies
14.1. Actemra / RoActemra (Tocilizumab): Roche Holding
14.1.1. Drug Description
14.1.2. Regulatory Milestones
14.1.3. Other Developmental Activities
14.1.4. Pivotal Clinical Trial
14.1.5. Ongoing Current Pipeline Activity
15. Emerging Therapies
15.1. Rinvoq (upadacitinib): AbbVie
15.1.1. Drug Description
15.1.2. Other Developmental Activities
15.1.3. Clinical Development
15.2. Cosentyx (secukinumab): Novartis Pharmaceuticals
15.2.1. Drug Description
15.2.2. Other Developmental Activities
15.2.3. Clinical Development
15.2.4. Safety and Efficacy
15.3. KPL-301 (mavrilimumab): CSL/Kiniksa Pharmaceuticals
15.3.1. Drug Description
15.3.2. Other Developmental Activities
15.3.3. Clinical Development
15.3.4. Safety and Efficacy
15.4. Tremfya (guselkumab): Johnson & Johnson/MorphoSys AG
15.4.1. Drug Description
15.4.2. Other Developmental Activities
15.4.3. Clinical Development
16. Giant Cell Arteritis (GCA): 7 Major Market Analysis
16.1. Key Findings
17. Market Outlook
17.1. Market Size of Giant Cell Arteritis (GCA)
17.1.1. Total Market Size of GCA
17.1.2. Market Size of Giant Cell Arteritis by Therapies
18. Market Access and Reimbursement
18.1. Key HTA decisions for Giant Cell Arteritis (GCA)
18.2. Reimbursement
18.3. Patient Access Programs
19. KOL Views20. Market Drivers21. Market Barriers22. SWOT Analysis23. Unmet Needs
24. Appendix
24.1. Bibliography
24.2. Report Methodology
25. Capabilities26. Disclaimer27. About the Publisher
List of Tables
Table 1: Summary of Giant Cell Arteritis (GCA), Market, Epidemiology, and Key Events (2018-2030)
Table 2: Revised ACR criteria (rACR) for diagnosis of GCA
Table 3: Recommendations for diagnostic testing in GCA
Table 4: Recommendations concerning GCA diagnosis
Table 5: Recommendations/statements for treatment (medical management and surgical intervention) and clinical/laboratory monitoring in GCA
Table 6: Recommendations concerning GCA management
Table 7: Total Prevalent Cases of Giant Cell Arteritis (2018-2030)
Table 8: Total Subtype-specific Cases of Giant Cell Arteritis (2018-2030)
Table 9: Total Age group-specific Cases of Giant Cell Arteritis (2018-2030)
Table 10: Total Clinical Manifestation-specific Cases of Giant Cell Arteritis (2018-2030)
Table 11: Total Treated Cases of Giant Cell Arteritis (2018-2030)
Table 12: Actemra/RoActemra (tocilizumab), Clinical Trial Description, 2021
Table 13: Rinvoq (upadacitinib), Clinical Trial Description, 2021
Table 14: Secukinumab (KPL-301), Clinical Trial Description, 2021
Table 15: KPL-301 (mavrilimumab), 2021
Table 16: Tremfya (Guselkumab): 2021
Table 17: 7MM Market Size of Giant Cell Arteritis in USD Million (2018-2030)
Table 18: 7MM Market Size of Giant Cell Arteritis by Therapies in USD Million (2018-2030)
Table 19: Key HTA Decisions
List of Figures
Figure 1: Epidemiology and Market Methodology
Figure 2: Profile of head showing the GCA in the human body
Figure 3: Brief description of Giant Cell Arteritis
Figure 4: Causes of GCA
Figure 5: Symptoms of GCA
Figure 6: Complication of GCA
Figure 7: Clinical Manifestations involved in GCA
Figure 8: Pathophysiology of GCA
Figure 9: Diagnostic algorithm for evaluation of suspected GCA
Figure 10: Diagnostic tests involved in GCA
Figure 11: Preoperative appearance of a patient with a prominent left superficial temporal artery
Figure 12: "Halo-sign" on temporal and axillary arteries
Figure 13: Cranial involvement pattern
Figure 14: Sagittal PET (A, B), coronal PET and fused PET/CT (C-F), and axial PET (G-I)
Figure 15: Showing the temporal artery for biopsy
Figure 16: Figure showing picture of biopsy in a patient
Figure 17: Treatment Algorithm of Giant Cell Arteritis
Figure 18: Total Prevalent Cases of Giant Cell Arteritis in the 7MM (2018-2030)
Figure 19: Total Subtype-specific Cases of Giant Cell Arteritis in the 7MM (2018-2030)
Figure 20: Total Age group-specific Cases of Giant Cell Arteritis in the 7MM (2018-2030)
Figure 21: Total Clinical Manifestation-specific Cases of Giant Cell Arteritis in the 7MM (2018-2030)
Figure 22: Total Treated Cases of Giant Cell Arteritis in the 7MM (2018-2030)
Figure 23: Market Size of Giant Cell Arteritis in the 7MM, USD Million (2018-2030)
Figure 24: 7MM Market Size of Giant Cell Arteritis by Therapies in USD Million (2018-2030)

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Roche Holding
  • AbbVie
  • Novartis Pharmaceuticals
  • CSL/Kiniksa Pharmaceuticals
  • Johnson & Johnson/MorphoSys AG