Wound Healing, Tissue Repair and Regeneration in Diabetes explores a wide range of topics related to wound healing, tissue repair and regeneration, putting a special focus on diabetes and obesity. The book addresses the molecular and cellular pathways involved in the process of wound repair and regeneration. Other sections explore a wide spectrum of nutritional supplements and novel therapeutic approaches, provide a comprehensive overview, present various types of clinical aspects related to diabetic wounds, including infection, neuropathy, and vasculopathy, provide an exhaustive review of various foods, minerals, supplements and phytochemicals that have been proven beneficial, and assess future directions.
This book is sure to be a welcome resource for nutritionists, practitioners, surgeons, nurses, wound researchers and other health professionals.
- Explains diabetic wounds and their complications
- Assesses the role of nutraceuticals, herbal supplements and other modalities for use in treating diabetic wounds
- Provides protocols for diabetic wound management
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Table of Contents
Part 1: Background and Overview 1. Concept and stages of wound healing 2. Pathophysiology of Diabetic ulcers 3. Wound infection and inflammation 4. The Angiogenic Response 5. Fetal Wound Healing 6. The Extracellular matrix: its formation and role in wound healing 7. Scarring and fibrosis 8. Role of cytokines and chemokines in wound healing 9. Dysregulated inflammation in diabetic wounds 10. Role of oxygen in diabetic wound healing 11. Epigenetics of diabetic wound healing 12. Tissue regeneration 13. Energetics and nutritional status of chronic and diabetic wounds 14. Epidemiology of Diabetic woundsPart Two: Clinical Update and Therapeutic Standards 15. Wound management and its principles 16. Chronic wounds and its menaces 17. Surgical Debridement and NPWT 18. Clinical management of DFU 19. Diabetic neuropathy 20. Malignant wounds
Part Three: Therapeutic Interventions 21. Biomaterials used to treat diabetic wounds 22. Peptides to treat diabetic wounds 23. Nutraceutical interventions of wound healing and inflammation 24. Papaya: A natural remedy for diabetic wounds 25. Role of berries in wound healing
Part Four: Future Directions 26. MiRNA in diabetic wound healing 27. Electroceuticals: an emerging field in wound healing 28. Nano-electroporation and reprogramming