Pediatric Reference Intervals. Edition No. 8

Table of Contents

Foreword

Preface

Introduction

�1 Chemistry tests

Acylcarnitine Profile�

Adiponectin

Adrenocorticotropic Hormone (ACTH)

Alanine Aminotransferase (ALT, SGPT)

Albumin

Aldolase

Aldosterone

Alkaline Phosphatase (ALP)

Alkaline Phosphatase, Bone-Specific

Alpha-1 Antitrypsin

Alpha-Fetoprotein (AFP)

Amino Acids, Plasma

Alanine

b-Alanine

a-Aminoadipic Acid

a-Aminobutyric Acid

g-Aminobutyric Acid

b-Aminoisobutyric Acid

Anserine

Arginine

Asparagine

Aspartate

Carnosine

Citrulline

Cystathionine

Cystine

Ethanolalanine

Glutamate

Glutamine

Glycine

Histidine

Homocystine

Hydroxylysine

Hydroxyproline

Isoleucine

Leucine

Lysine

Methionine

1-Methyl-histidine

3-Methyl-histidine

Ornithine

Phenylalanine

Phosphoethanolamine

Phosphoserine

Proline

Sarcosine

Serine

Taurine

Threonine

Tryptophan

Tyrosine

Valine

Amino Acids, Urine

Alanine

b-Alanine

a-Aminoadipic Acid

a-Aminobutyric Acid

g-Aminobutyric Acid

b-Aminoisobutyric Acid

Anserine

Arginine

Asparagine

Aspartate

Carnosine

Citrulline

Cystathionine

Cystine

Ethanolamine

Glutamate

Glutamine

Glycine

Histidine

Homocystine

Hydroxylysine

Hydroxyproline

Isoleucine

Leucine

Lysine

Methionine

1-Methyl-histidine

3-Methyl-histidine

Ornithine

Phenylalanine

Phosphoethanolamine

Phosphoserine

Proline

Sarcosine

Serine

Taurine

Threonine

Tryptophan

Tyrosine

Valine

Amylase

Amylase, Pancreatic

Androstenedione

Anti-Mu�llerian Hormone (AMH)

Antistreptolysin O (ASO)

Apolipoprotein A

Apolipoprotein B

Aspartate Aminotransferase (AST, SGOT)

b-Hydroxybutyrate/3-Hydroxybutyrate

b2-Microglobulin

Base Excess

Bile Acids, Total 3a-Hydroxy Bile Acids

Bilirubin, Conjugated

Bilirubin, Total

Brain Natriuretic Peptide (BNP)

N-Terminal Pro-Brain Natiuretic Peptide (NT-proBNP)

�C-Peptide

C-Reactive Protein (CRP)

C-Telopeptide

Calcium, Serum/Plasma

Calcium, Urine

Carbon Dioxide (CO2)

Carboxyhemoglobin (COHb)

Carnitine, Total

Ceruloplasmin

Chloride

Cholesterol

Cholinesterase Dibucaine Number

Citrate, Urine

Creatine KinaseeMB isoform (CK-MB)

Complement FractiondC3c

Complement FractiondC4

Copper

Corticosterone

Cortisol, Serum

Cortisol, Urinary Free

Creatine Kinase (CK)

Creatinine

Cystatin C

Dehydroepiandrosterone (DHEA)

Dehydroepiandrosterone Sulfate (DHEAS)

Deoxycorticosterone (DOC)

11-Deoxycortisol (Compound S)

Dihydrotestosterone (DHT)

Dopamine, Urine

Epinephrine, Serum

Epinephrine, Urine

Estradiol

Estrone

Ferritin

Folate

Follicle Stimulating Hormone (FSH)

Free Fatty Acids

Gamma-Glutamyltransferase (GGT)

Glucose

Growth Hormone

Haptoglobin

High-Density Lipoprotein Cholesterol (HDL-C)

Homocysteine, Total

Homovanillic Acid (HVA; 4-Hydroxy-3-Methoxyphenylacetic Acid), Urine

Beta Human Chorionic Gonadotropin (beta-hCG)

17-hydroxypregnenolone

17a-Hydroxyprogesterone (17a-OHP)

lmmunoglobulin A (IgA)

Immunoglobulin E (IgE)

Immunoglobulin G (IgG)

Immunoglobulin G1 (IgG1)

Immunoglobulin G2 (IgG2)

Immunoglobulin G3 (IgG3)

Immunoglobulin G4 (IgG4)

Immunoglobulin M (IgM)

Insulin

Insulin-like Growth Factor Binding Protein-3 (IGFBP-3)

Insulin-like Growth Factor-1 (IGF-1)

Iron

Total Iron Binding Capacity

Lactate, Serum/Plasma

Lactate, CSF

Lactate Dehydrogenase

Leptin

Lipase

Lipoprotein (a)

Low-Density Lipoprotein-Cholesterol (LDL-C)

Luteinizing Hormone (LH)

Magnesium

Metanephrine, Urine

Mucopolysaccharides, Urine

Myoglobin

N-Telopeptide (NTx), Urine

Norepinephrine/Noradrenaline, Plasma

Norepinephrine/Noradrenaline, Urine

Normetanephrine, Urine

Osmolality, Urine

Osteocalcin

Oxalate, Urine

Oxygen Saturation

Parathyroid Hormone (PTH)

Phosphorus, Serum/Plasma

Phosphorus, Urine

Potassium

Prealbumin (Transthyretin)

Pregnenolone

Procalcitonin

Progesterone

Prolactin

Protein, Total

Protein, CSF

Rheumatoid Factor

Selenium

Sex Hormone Binding Globulin (SHBG)

Sodium, Serum

Sodium, Urine

Soluble Transferrin Receptor

Testosterone

Testosterone, Free

Thyroid Stimulating Hormone (TSH)

Thyroxine (T4)

Thyroxine-Binding Globulin (TBG)

Thyroxine, Free (Free T4)

Transferrin

Transferrin Saturation

Triglycerides

Triiodothyronine (T3)

Triiodothyronine, Free (Free 13)

Troponin I

Troponin T

Urea Nitrogen

Uric Acid

Vanillylmandelic Acid (VMA; 4-Hydroxy-3-Methoxymandelic Acid), Urine

Vitamin A

Vitamin B12

1,25 Dihydroxy Vitamin D

25-Hydroxy Vitamin D

206 Vitamin E (a-Tocopherol)

Zinc

2 Hematology tests

Basophil Count, Absolute

Basophil Count, Relative

Eosinophil Count, Absolute

Eosinophil Count, Relative

Hematocrit

Hemoglobin

Immature Granulocyte Count (IG), Absolute

Immature Granulocyte Count (IG), Relative

Immature Platelet Count (IPC)

Immature Platelet Fraction (IPF)

Lymphocyte Count, Absolute

Lymphocyte Count, Relative

Mean Corpuscular Hemoglobin (MCH)

Mean Corpuscular Hemoglobin Concentration (MCHC)

Mean Corpuscular Volume (MCV)

Mean Platelet Volume (MPV)

Monocyte Count, Absolute

Monocyte Count, Relative

Neutrophil Count, Absolute

Neutrophil Count, Relative

Nucleated Red Blood Cell Count (Absolute)

Platelet Count

RBC Count

Red Cell Distribution Width (RDW)

Reticulocyte Count, Absolute

Reticulocyte Count, Relative

Reticulocyte Hemoglobin Content

WBC Count

Additional Reading

3 Coagulation tests

Activated Partial Thromboplastin Time

ADAMTS13 Activity

Alpha 2- Antiplasmin

Antithrombin Activity

D-Dimer

Factor II

Factor V

Factor VII

Factor VIII

Factor IX

Factor X

Factor XI

Factor XII

Factor XIII

Fibrinogen Activity, Clauss

Plasminogen

Protein C Activity

Protein C Antigen

Protein S Activity

Protein S Antigen, Free

Protein S Antigen, Total

Prothrombin Time

TEG Parameters, Kaolin-Activated (Citrated Whole Blood)

TEG Parameters, Kaolin-Activated (Whole Blood Only)

Thrombin Clotting Time

Tissue Factor Protein Inhibitor, Total

Von Willebrand Factor Activity

Von Willebrand Factor Antigen

Von Willebrand Factor: Collagen Binding

Additional Reading

Authors

Edward C.C. Wong Medical Director, Coagulation/Blood Bank, Quest Diagnostics/Nichols Institute, Chantilly, VA, USA. Edward Wong FCAP is Medical Director, Coagulation, Quest Diagnostics Nichols Institute; Adjunct Associate Professor in Pediatrics and Pathology, George Washington School of Medicine and Health Sciences, Clinical Consultant at Children's National Hospital in the Divisions of Pathology and Laboratory Medicine; and Hematology, Washington DC, USA Carlo Brugnara Director, Hematology Lab Professor of Pathology, Harvard Medical School, Boston, MA, USA. Carlo Brugnara is the Medical Director of Boston Children's Hospital & Department of Pathology, Harvard Medical School Joely Straseski PhD, DABCC, University of Utah, ARUP Laboratories, Salt Lake City, UT. Joely Straseski DABCC works at University of Utah in the ARUP Laboratories, Salt Lake City, UT Mark Kellogg PhD, DABCC, Department of Laboratory Medicine, Boston Children's Hospital and the Department of Pathology, Harvard Medical School, Boston, MA. Dr. Mark Kellogg works in the Department of Laboratory Medicine at Boston Children's Hospital. Khosrow Adeli PhD, University of Toronto, Departments of Biochemistry and Laboratory Medicine & Pathology, Toronto, Ontario, Canada. Khosrow Adeli works in the Departments of Biochemistry and Laboratory Medicine and Pathology at University of Toronto, Toronto, Ontario, Canada