High-Performance Liquid Chromatography (HPLC) - Market Share Analysis, Industry Trends & Statistics, Growth Forecasts 2019 - 2029

The High-Performance Liquid Chromatography (HPLC) Market size is expected to grow from USD 4.8 billion in 2024 to USD 5.95 billion by 2029, witnessing a CAGR of 4.45% during the forecast period.

The COVID-19 pandemic significantly impacted the high-performance liquid chromatography (HPLC) market. For instance, a study published in the Journal of Pharmaceutical and Biomedical Analysis in May 2022 studied the permeability quantitation of Molnupiravir in nanoformulations. The study estns. The study established that the reversed-phase HPLC method is more applicable for the routine analysis of Molnupiravir compared to the Liquid Chromatography - Mass Spectrometry / Mass Spectrometry methods. Furthermore, according to an article published by WHO in November 2021, the established method HPLC was employed to quantify remdesivir in marketed pharmaceutical formulations. The rise in the applications of HPLC systems in the COVID-19 study propelled the growth of the studied market. However, as the COVID-19 cases started to decline, the market began to show normal pre-pandemic level growth and is likely to continue its significant growth rate during the forecast period.

Factors such as advancements in HPLC technologies and the surge in usage of HPLC in pharmaceutical and bio-pharmaceutical companies are expected to drive the market's growth over the forecast period. For instance, according to an article published in the Journal of Current Opinion in Chemical Engineering in June 2021, HPLC is highly versatile, used for fast analysis and high-yield separation at both preparative and process scales, and is the most common separation method in the production of pharmaceutical and biopharmaceutical products. The article indicated that the combination of computational and experimental work could help the adoption of more complex models, reduce the simulation time, and facilitate faster screening of multidimensional operation spaces for parameter estimation and optimization. The advances made in the HPLC sector will likely add to the market growth in the forecast period.

Several key market players have also been interested in developing and manufacturing innovative HPLC-based systems for various laboratory functions, including diagnostics. For instance, in June 2021, Trivitron Healthcare launched HPLC-based diagnostic solutions, the HbA1c analyzers for monitoring diabetes, thalassemia, and hemoglobin variants. The fully automated NANO H5 analyzer can process five samples at a time. The NANO H110 is a compact, automated HPLC analyzer with a dual test mode for HbA1c test and Hb Variant detection, with a high sample loading capacity of 110 samples at a time. Such innovations are expected to propel market growth in the study period.

However, the lack of skilled personnel and the high cost of the HPLC systems will likely hinder the market growth in the forecast period.

High-Performance Liquid Chromatography (HPLC) Market Trends

Consumables Segment is Expected to Hold a Significant Share in the High-Performance Liquid Chromatography (HPLC) Market

HPLC consumables are the columns, reagents, tubes, and other products that are used for high-performance liquid chromatography techniques. Due to the advancements in column technologies and pumps, the segment is anticipated to grow at significant rates. The pharma and biopharmaceutical companies manufacturing HPLC systems are anticipated to grow at a significant rate owing to the increasing need for the development of new therapeutics to address the growing prevalence of chronic diseases around the world and an increase in government expenditure in research and development of biotechnology. For instance, according to a study published by Analytical Liquid Chromatography in May 2022, the chromatographic column is an essential part of HPLC separation. Significant progress has been made in developing columns with better performance to provide better separation, a shorter separation time, resilience to a wider pH range of the mobile phase, longer lifetime, use of lower volumes of the mobile phase, etc. Such advancements in these columns are expected to drive segmental growth.

Recent advances made by the market players in the research and development of novel HPLC techniques are also adding to the market's growth. For instance, in February 2022, Thermo Fisher Scientific launched a new portfolio of high-performance chromatography and mass spectrometry consumables called SureStart, which includes a new collection of caps, vials, inserts, kits, well plates, and mats. The Thermo Scientific SureStart portfolio is compatible with all add-ons and chromatography autosamplers, allowing analysts to use the new portfolio in all systems. Such research and developments in High-Performance Liquid Chromatography (HPLC) techniques are expected to propel the market growth over the forecast period.

Thus, owing to the abovementioned factors, the consumables segment is expected to project significant growth over the forecast period.

North America is Expected to Hold a Significant Share in the Market Over the Forecast Period

The rise in the adoption of highly advanced techniques and systems in manufacturing High-Performance Liquid Chromatography (HPLC) and the technological advancements made in chromatographic studies is expected to boost the market's growth in the North American region. The high awareness among the research personnel on the availability of innovative chromatography studies in the market contributes to the increased market growth in the area. Various governmental research organizations in the United States use the HPLC technique to analyze specific components in a drug mixture or similar elements. An article published by the United States Environmental Protection Agency, updated in May 2021, on the High-PerformanceEnvironmental Sampling and Analytical Methods (ESAM) Program focused on Determining Carbonyl Compounds by using High-Performance Liquid Chromatography (HPLC). Such application of HPLC techniques as standard protocols for sample analysis adds to the market's growth in the North American region.

The launch of innovative High-Performance Liquid Chromatography (HPLC) systems by the key market players also adds to the market's growth. For instance, in February 2021, Waters launched ACQUITY PREMIER Liquid Chromatography Solution, which combines the ACQUITY PREMIER System with ACQUITY PREMIER Columns with MaxPeak HPS technology. It is designed to alleviate the problem of analyte/metal surface interactions when analyzing organic acids, organophosphates, oligonucleotides, phosphopeptides, acidic glycans, and phospholipids by reversed-phase and hydrophilic interaction chromatography. Such activities are expected to propel market growth over the forecast period.

Thus, the increasing necessity for High-Performance Liquid Chromatography (HPLC) is known to propel the market growth in this region.

High-Performance Liquid Chromatography (HPLC) Industry Overview

The High-Performance Liquid Chromatography (HPLC) market is fragmented in nature due to the presence of several companies operating globally as well as regionally. The competitive landscape includes an analysis of a few international as well as local companies that hold significant market shares and are well known, including Merck KGaA, Bio-Rad Laboratories Inc., Mitsubishi Chemical Corporation, Tosoh Corporation, and General Electric (Cytiva Life Sciences).

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