Fundamentals of Free Radicals and Synthetic Strategies for Organic Synthesis, Second Edition, presents the most recent advances and useful free radical reactions for synthetic organic chemists. This new and updated edition reviews information on all types of practical radical reactions, e.g. cyclizations, additions, hydrogen-atom abstractions and decarboxylation reactions. The book provides experimental details for the most important reactions as well as numerous references to the original literature. By covering both the fundamentals and synthetic applications, it is suitable for both new and experienced researchers, chemists, biochemists, natural product chemists and graduate students.
Table of Contents
1. Fundamentals for Free Radicals2. Functional Group Transformation
3. Intramolecular Radical Cyclizations
4. Intermolecular Radical Addition Reactions
5. Alkylation of Aromatics and Heteroaromatics
6. Intramolecular Hydrogen-Atom Abstraction
7. Synthetic Uses of Free Radicals for Nucleosides and Sugars
8. Barton Decarboxylation Reaction with Carboxylic Acids
9. Whol-Ziegler Reaction and Fenton Reaction
10. Free Radical Reactions with Metal Hydrides
11. 1,2-Rearrangement of Acyloxy and Related Groups
12. Stereoselective Radical Reactions
13. Free Radicals Related to Biology
14. Synthetic Uses of Free Radicals for Natural Products and Pharmaceuticals