Systems and Synthetic Metabolic Engineering provides an overview of the development of metabolic engineering within medicine that is fueled by systems and synthetic biology. These newly developed, successful strategies of metabolic engineering guide the audience on how to propose and test proper strategies for metabolic engineering research. In addition to introductory, regulatory and challenges in the field, the book also covers dynamic control and autonomous regulation to control cell metabolism, along with computational modeling and industrial applications. The book is written by leaders in the field, making it ideal for synthetic biologists, researchers, students and anyone working in this area.
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Table of Contents
1. Systems biology, synthetic biology and metabolic engineering2. Synthetic regulatory elements for fine-tuning gene expression3. Systems and synthetic biology-aided biosynthesis pathway design4. Refactoring and optimization of metabolic network5. Harnessing the hierarchy of transcriptional regulation: engineering of the gene expression network for efficient production of biofuels6. Systems metabolic engineering strategies for cell factories construction7. High throughput screening for improving cellular and enzymatic properties8. In vitro metabolic engineering: current status and recent progress9. Systems and synthetic metabolic engineering for production of biochemicals10. Systems and synthetic metabolic engineering: Challenges and prospects